BR0109802A - Preparações farmacêuticas e sua fabricação - Google Patents
Preparações farmacêuticas e sua fabricaçãoInfo
- Publication number
- BR0109802A BR0109802A BR0109802-0A BR0109802A BR0109802A BR 0109802 A BR0109802 A BR 0109802A BR 0109802 A BR0109802 A BR 0109802A BR 0109802 A BR0109802 A BR 0109802A
- Authority
- BR
- Brazil
- Prior art keywords
- emulsion
- pharmaceutical preparations
- particles
- active substance
- manufacture
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 239000002245 particle Substances 0.000 abstract 4
- 239000013543 active substance Substances 0.000 abstract 3
- 239000000839 emulsion Substances 0.000 abstract 3
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Colloid Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
"PREPARAçõES FARMACêUTICAS E SUA FABRICAçãO". Um método para preparar uma composição compreendendo partículas ativas, que compreendem uma substância ativa, compreende as etapas de a) proporcionar uma emulsão tendo uma fase dispersa compreendendo uma solução da substância ativa em um solvente e b) induzir a formação, na emulsão, de partículas sólidas compreendendo a substância ativa. As partículas podem ser isoladas da emulsão. São proporcionadas partículas ativas tendo uma curtose normalizada de pelo menos 5 e um diâmetro médio de menos do que 100 <109>m.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0008411.1A GB0008411D0 (en) | 2000-04-05 | 2000-04-05 | Pharmaceutical preparations and their manufacture |
PCT/GB2001/001562 WO2001074332A1 (en) | 2000-04-05 | 2001-04-05 | Pharmaceutical preparations and their manufacture |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0109802A true BR0109802A (pt) | 2003-01-21 |
Family
ID=9889294
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0109802-0A BR0109802A (pt) | 2000-04-05 | 2001-04-05 | Preparações farmacêuticas e sua fabricação |
Country Status (22)
Country | Link |
---|---|
US (2) | US20030157182A1 (pt) |
EP (1) | EP1267833B1 (pt) |
JP (1) | JP2003528907A (pt) |
KR (1) | KR20030011816A (pt) |
CN (1) | CN1420764A (pt) |
AT (1) | ATE269057T1 (pt) |
AU (1) | AU4440601A (pt) |
BR (1) | BR0109802A (pt) |
CA (1) | CA2404367A1 (pt) |
DE (1) | DE60103865T2 (pt) |
DK (1) | DK1267833T3 (pt) |
ES (1) | ES2218402T3 (pt) |
GB (1) | GB0008411D0 (pt) |
HU (1) | HUP0300334A3 (pt) |
IL (1) | IL152074A0 (pt) |
MX (1) | MXPA02009797A (pt) |
NO (1) | NO20024737L (pt) |
PL (1) | PL357808A1 (pt) |
PT (1) | PT1267833E (pt) |
TR (1) | TR200401567T4 (pt) |
WO (1) | WO2001074332A1 (pt) |
ZA (1) | ZA200207508B (pt) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109890225A (zh) * | 2016-11-10 | 2019-06-14 | 日本烟草产业株式会社 | 球状的粉末凝聚体及其制造方法 |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004073827A1 (en) * | 2003-02-21 | 2004-09-02 | The University Of Bath | Process for the production of particles |
GB0425758D0 (en) * | 2004-11-23 | 2004-12-22 | Vectura Ltd | Preparation of pharmaceutical compositions |
GB0426301D0 (en) * | 2004-11-30 | 2004-12-29 | Vectura Ltd | Pharmaceutical formulations |
JP5243247B2 (ja) * | 2005-07-28 | 2013-07-24 | アイエスピー インヴェストメンツ インコーポレイテッド | スプレー乾燥された粉体及び粒状化された材料の特性の改良方法、並びにそれによって製造した製品 |
JP2007326083A (ja) * | 2006-06-09 | 2007-12-20 | Fujifilm Corp | 固体微粒子及びその製造方法 |
US20080085315A1 (en) * | 2006-10-10 | 2008-04-10 | John Alfred Doney | Amorphous ezetimibe and the production thereof |
CN101541415B (zh) * | 2006-11-14 | 2012-08-22 | 巴斯夫欧洲公司 | 生产亚微核/壳粒子的微悬浮乳液或悬浮液的方法 |
WO2008076780A2 (en) * | 2006-12-14 | 2008-06-26 | Isp Investments Inc. | Amorphous valsartan and the production thereof |
US8613946B2 (en) * | 2006-12-21 | 2013-12-24 | Isp Investment Inc. | Carotenoids of enhanced bioavailability |
EP2125938A2 (en) * | 2007-01-26 | 2009-12-02 | Isp Investments Inc. | Formulation process method to produce spray dried products |
US20080181961A1 (en) * | 2007-01-26 | 2008-07-31 | Isp Investments, Inc. | Amorphous oxcarbazepine and the production thereof |
PL220269B1 (pl) | 2008-04-21 | 2015-09-30 | Przedsiębiorstwo Produkcji Farmaceutycznej Hasco Lek Spółka Akcyjna | Kompozytowy nośnik leków proszkowych, sposób wytwarzania nośnika leków oraz urządzenie do wytwarzania cząstek nośnika kompozytowego |
MX2011000410A (es) | 2008-07-18 | 2011-03-24 | Prosonix Ltd | Proceso para mejorar la cristalinidad de particulas de fluticasona. |
CN102107127B (zh) * | 2011-01-11 | 2015-04-22 | 西安蓝晓科技新材料股份有限公司 | 一种粉体造粒技术 |
EP2731627A4 (en) * | 2011-07-15 | 2015-06-17 | Eupharma Pty Ltd | ORAL COMPOSITIONS WITH ANTAZID, ANESTHETIC AND INORGANIC MATRIX WITH SILICON DIOXIDE AND TITANIUM DIOXIDE |
PT107433B (pt) * | 2014-01-28 | 2018-12-04 | Hovione Farm S A | Processo de redução e controlo do tamanho de partícula |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2608988B1 (fr) * | 1986-12-31 | 1991-01-11 | Centre Nat Rech Scient | Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules |
SE464743B (sv) * | 1989-06-21 | 1991-06-10 | Ytkemiska Inst | Foerfarande foer framstaellning av laekemedelspartiklar |
FR2694895B1 (fr) * | 1992-08-20 | 1994-11-10 | Coletica | Procédé de fabrication de microparticules en émulsion par modification de la composition chimique de la phase dispersée après émulsification. |
EP1649850A1 (en) * | 1993-11-19 | 2006-04-26 | Alkermes Controlled Therapeutics Inc. II | Preparation of biodegradable microparticles containing a biologically active agent |
US6214331B1 (en) * | 1995-06-06 | 2001-04-10 | C. R. Bard, Inc. | Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained |
DE19617085A1 (de) * | 1996-04-29 | 1997-10-30 | Bayer Ag | Verfahren zur Herstellung von feinstteiligen Kristallisationsprodukten |
US5792477A (en) * | 1996-05-07 | 1998-08-11 | Alkermes Controlled Therapeutics, Inc. Ii | Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent |
GB9700624D0 (en) * | 1997-01-14 | 1997-03-05 | Danbiosyst Uk | Drug delivery composition |
US6150505A (en) | 1997-09-19 | 2000-11-21 | Hadasit Medical Research Services & Development Ltd. | Fibrin microbeads prepared from fibrinogen, thrombin and factor XIII |
US6565885B1 (en) * | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
-
2000
- 2000-04-05 GB GBGB0008411.1A patent/GB0008411D0/en not_active Ceased
-
2001
- 2001-04-05 ES ES01917326T patent/ES2218402T3/es not_active Expired - Lifetime
- 2001-04-05 CN CN01807483A patent/CN1420764A/zh active Pending
- 2001-04-05 KR KR1020027013213A patent/KR20030011816A/ko not_active Application Discontinuation
- 2001-04-05 MX MXPA02009797A patent/MXPA02009797A/es active IP Right Grant
- 2001-04-05 WO PCT/GB2001/001562 patent/WO2001074332A1/en active IP Right Grant
- 2001-04-05 DE DE60103865T patent/DE60103865T2/de not_active Expired - Lifetime
- 2001-04-05 BR BR0109802-0A patent/BR0109802A/pt not_active IP Right Cessation
- 2001-04-05 US US10/240,890 patent/US20030157182A1/en not_active Abandoned
- 2001-04-05 CA CA002404367A patent/CA2404367A1/en not_active Abandoned
- 2001-04-05 IL IL15207401A patent/IL152074A0/xx unknown
- 2001-04-05 TR TR2004/01567T patent/TR200401567T4/xx unknown
- 2001-04-05 EP EP01917326A patent/EP1267833B1/en not_active Revoked
- 2001-04-05 AU AU44406/01A patent/AU4440601A/en not_active Abandoned
- 2001-04-05 HU HU0300334A patent/HUP0300334A3/hu unknown
- 2001-04-05 JP JP2001572077A patent/JP2003528907A/ja active Pending
- 2001-04-05 PL PL01357808A patent/PL357808A1/xx not_active Application Discontinuation
- 2001-04-05 PT PT01917326T patent/PT1267833E/pt unknown
- 2001-04-05 DK DK01917326T patent/DK1267833T3/da active
- 2001-04-05 AT AT01917326T patent/ATE269057T1/de active
-
2002
- 2002-09-19 ZA ZA200207508A patent/ZA200207508B/en unknown
- 2002-10-02 NO NO20024737A patent/NO20024737L/no not_active Application Discontinuation
-
2009
- 2009-02-25 US US12/380,280 patent/US20100015234A1/en not_active Abandoned
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109890225A (zh) * | 2016-11-10 | 2019-06-14 | 日本烟草产业株式会社 | 球状的粉末凝聚体及其制造方法 |
Also Published As
Publication number | Publication date |
---|---|
US20030157182A1 (en) | 2003-08-21 |
AU4440601A (en) | 2001-10-15 |
EP1267833A1 (en) | 2003-01-02 |
GB0008411D0 (en) | 2000-05-24 |
PT1267833E (pt) | 2004-11-30 |
NO20024737D0 (no) | 2002-10-02 |
CN1420764A (zh) | 2003-05-28 |
TR200401567T4 (tr) | 2004-08-23 |
PL357808A1 (en) | 2004-07-26 |
ATE269057T1 (de) | 2004-07-15 |
IL152074A0 (en) | 2003-05-29 |
DE60103865D1 (de) | 2004-07-22 |
DE60103865T2 (de) | 2004-10-28 |
ZA200207508B (en) | 2003-09-19 |
DK1267833T3 (da) | 2004-07-19 |
HUP0300334A2 (hu) | 2003-09-29 |
US20100015234A1 (en) | 2010-01-21 |
EP1267833B1 (en) | 2004-06-16 |
CA2404367A1 (en) | 2001-10-11 |
JP2003528907A (ja) | 2003-09-30 |
KR20030011816A (ko) | 2003-02-11 |
NO20024737L (no) | 2002-11-18 |
ES2218402T3 (es) | 2004-11-16 |
WO2001074332A1 (en) | 2001-10-11 |
MXPA02009797A (es) | 2004-09-13 |
HUP0300334A3 (en) | 2005-04-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25G | Requested change of headquarter approved |
Owner name: VECTURA LIMITED (GB) Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 020060042098/RJ DE 27/03/2006. |
|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 8A. ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO DA RPI 2016 DE 25/08/2009. |