BR0109127A - Dispositivos inaladores de pó seco, embalagens de múltiplas dosagens de droga de pó seco, sistemas de controle, e métodos associados - Google Patents
Dispositivos inaladores de pó seco, embalagens de múltiplas dosagens de droga de pó seco, sistemas de controle, e métodos associadosInfo
- Publication number
- BR0109127A BR0109127A BR0109127-1A BR0109127A BR0109127A BR 0109127 A BR0109127 A BR 0109127A BR 0109127 A BR0109127 A BR 0109127A BR 0109127 A BR0109127 A BR 0109127A
- Authority
- BR
- Brazil
- Prior art keywords
- dry powder
- control systems
- user
- associated methods
- drug packaging
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Detergent Compositions (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
"DISPOSITIVOS INALADORES DE Pó SECO, EMBALAGENS DE MúLTIPLAS DOSAGENS DE DROGA DE Pó SECO, SISTEMAS DE CONTROLE, E MéTODOS ASSOCIADOS". A presente invenção trata de inaladores de pó seco (Figura 1) dotados de sistemas de dispersão de energia ativa integrados de auxílio ao paciente, os inaladores são configurados com sistemas de controle que proporcionam uma saída de energia ajustável responsiva à capacidade inspiratória do usuário e/ou pó seco que é administrado. A embalagem de múltiplas dosagens de droga de pó seco (Figura 2) é dotada de um substrato de polímero piezoelétrico que se flexiona para deformar e proporciona oscilação mecânica em uma região selecionada da embalagem que corresponde à droga de pó seco que é dispersada durante a inalação pelo usuário. O sistema de controle (Figura 12) emprega lógica difusa para se relacionar a uma resposta do esforço inspiratório do usuário.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18854300P | 2000-03-10 | 2000-03-10 | |
PCT/US2001/002262 WO2001068169A1 (en) | 2000-03-10 | 2001-01-24 | Dry powder inhaler devices, multi-dose dry powder drug packages, control systems, and associated methods |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0109127A true BR0109127A (pt) | 2003-04-22 |
Family
ID=22693596
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0109127-1A BR0109127A (pt) | 2000-03-10 | 2001-01-24 | Dispositivos inaladores de pó seco, embalagens de múltiplas dosagens de droga de pó seco, sistemas de controle, e métodos associados |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1267969B1 (pt) |
JP (2) | JP4934798B2 (pt) |
KR (1) | KR20020086624A (pt) |
CN (1) | CN1179765C (pt) |
AT (1) | ATE366126T1 (pt) |
AU (2) | AU2001231102B2 (pt) |
BR (1) | BR0109127A (pt) |
CA (1) | CA2400349C (pt) |
DE (1) | DE60129214T2 (pt) |
ES (1) | ES2290110T3 (pt) |
MX (1) | MXPA02008605A (pt) |
NO (1) | NO20024311L (pt) |
PL (1) | PL201275B1 (pt) |
WO (1) | WO2001068169A1 (pt) |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
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US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
US6971383B2 (en) | 2001-01-24 | 2005-12-06 | University Of North Carolina At Chapel Hill | Dry powder inhaler devices, multi-dose dry powder drug packages, control systems, and associated methods |
GB0201677D0 (en) | 2002-01-25 | 2002-03-13 | Glaxo Group Ltd | Medicament dispenser |
ATE385193T1 (de) | 2002-03-20 | 2008-02-15 | Mannkind Corp | Inhalationsgerät |
US6889690B2 (en) | 2002-05-10 | 2005-05-10 | Oriel Therapeutics, Inc. | Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages |
DE60330776D1 (de) * | 2002-05-10 | 2010-02-11 | Oriel Therapeutics Inc | Trockenpulverinhalator mit einer durch piezoelektrisches polymer angetriebenen abgabevorrichtung, und zugehörige blisterverpackung mit einem piezoelektrischen polymermaterial |
SE0201847D0 (sv) * | 2002-06-14 | 2002-06-14 | Aerocrine Ab | Therapeutic device and method |
SE527069C2 (sv) | 2003-06-19 | 2005-12-13 | Mederio Ag | Förfarande och anordning för administrering av läkemedelspulver |
GB0317374D0 (en) | 2003-07-24 | 2003-08-27 | Glaxo Group Ltd | Medicament dispenser |
WO2005041848A2 (en) | 2003-10-27 | 2005-05-12 | Oriel Therapeutics, Inc. | Dry powder drug containment system packages with tabs, inhalers and associated methods |
US7377277B2 (en) * | 2003-10-27 | 2008-05-27 | Oriel Therapeutics, Inc. | Blister packages with frames and associated methods of fabricating dry powder drug containment systems |
FR2872798B1 (fr) * | 2004-07-09 | 2007-10-05 | Valois Sas | Ensemble de blisters pour dispositif d'inhalation |
GB0418278D0 (en) | 2004-08-16 | 2004-09-15 | Glaxo Group Ltd | Medicament dispenser |
CA2575692C (en) | 2004-08-20 | 2014-10-14 | Mannkind Corporation | Catalysis of diketopiperazine synthesis |
BR122019022692B1 (pt) | 2004-08-23 | 2023-01-10 | Mannkind Corporation | Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo |
US8210171B2 (en) | 2004-09-13 | 2012-07-03 | Oriel Therapeutics, Inc. | Tubular dry powder drug containment systems, associated inhalers and methods |
US8365725B2 (en) | 2004-09-13 | 2013-02-05 | Oriel Therapeutics, Inc. | Dry powder inhalers that inhibit agglomeration, related devices and methods |
GB0515584D0 (en) | 2005-07-28 | 2005-09-07 | Glaxo Group Ltd | Medicament dispenser |
DK1937219T3 (en) | 2005-09-14 | 2016-02-15 | Mannkind Corp | A method for drug formulation based on increasing the affinity of the crystalline surfaces of the microparticle of active principles |
IN2015DN00888A (pt) | 2006-02-22 | 2015-07-10 | Mannkind Corp | |
JP5241714B2 (ja) | 2006-07-07 | 2013-07-17 | プロテウス デジタル ヘルス, インコーポレイテッド | スマートな非経口送達システム |
GB0622827D0 (en) | 2006-11-15 | 2006-12-27 | Glaxo Group Ltd | Sheet driver for use in a drug dispenser |
US8261738B2 (en) * | 2007-07-24 | 2012-09-11 | Respironics Respiratory Drug Delivery (Uk) Ltd. | Apparatus and method for maintaining consistency for aerosol drug delivery treatments |
US8439033B2 (en) | 2007-10-09 | 2013-05-14 | Microdose Therapeutx, Inc. | Inhalation device |
EP2211974A4 (en) | 2007-10-25 | 2013-02-27 | Proteus Digital Health Inc | INFORMATION SYSTEM FOR LIQUID FLOW CHANNEL |
JP2011507593A (ja) * | 2007-12-20 | 2011-03-10 | アストラゼネカ・アクチエボラーグ | 粉末854を脱凝集解体する装置ならびに方法 |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
KR101933816B1 (ko) | 2008-06-13 | 2019-03-29 | 맨카인드 코포레이션 | 건조 분말 흡입기 및 약물 투여 시스템 |
EP2609954B1 (en) | 2008-06-20 | 2021-12-29 | MannKind Corporation | An interactive apparatus for real-time profiling of inhalation efforts |
TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
US10387621B2 (en) | 2009-01-16 | 2019-08-20 | Cerner Innovation, Inc. | Matching of vibratory inhalers to patient vocal tract for optimization of particle dispersion |
US8538707B2 (en) | 2009-03-11 | 2013-09-17 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
EA026215B1 (ru) * | 2009-05-21 | 2017-03-31 | Майкродоуз Терапьютикс, Инк. | Ротационная кассетная система для ингалятора сухого порошка |
AU2014221279B2 (en) * | 2009-05-21 | 2016-07-21 | Microdose Therapeutx, Inc. | Rotary cassette system for dry powder inhaler |
MY157166A (en) | 2009-06-12 | 2016-05-13 | Mankind Corp | Diketopiperazine microparticles with defined specific surface areas |
US20110000481A1 (en) * | 2009-07-01 | 2011-01-06 | Anand Gumaste | Nebulizer for infants and respiratory compromised patients |
EP2277576A1 (en) * | 2009-07-24 | 2011-01-26 | Vectura Delivery Devices Limited | Inhaler |
JP5784622B2 (ja) | 2009-11-03 | 2015-09-24 | マンカインド コーポレ−ション | 吸入活動をシミュレートするための装置及び方法 |
CA2784041C (en) * | 2010-01-05 | 2017-11-07 | Microdose Therapeutx, Inc. | Inhalation device and method |
JP5841951B2 (ja) | 2010-02-01 | 2016-01-13 | プロテウス デジタル ヘルス, インコーポレイテッド | データ収集システム |
EP2531096A4 (en) | 2010-02-01 | 2013-09-11 | Proteus Digital Health Inc | DATA COLLECTION SYSTEM FOR TWO WRIST |
RU2531455C2 (ru) | 2010-06-21 | 2014-10-20 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
US10154923B2 (en) | 2010-07-15 | 2018-12-18 | Eyenovia, Inc. | Drop generating device |
JP6133270B2 (ja) | 2011-04-01 | 2017-05-24 | マンカインド コーポレイション | 薬剤カートリッジのためのブリスター包装 |
EP2696711A4 (en) | 2011-04-12 | 2015-03-25 | Sis Resources Ltd | BATTERY CONNECTOR FOR ELECTRONIC CIGARETTE WITH SIDE AIR INTAKE |
CN102218182B (zh) * | 2011-06-13 | 2015-02-18 | 上海秀新臣邦医药科技有限公司 | 一种干粉给药装置的振动给药装置 |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
US9852267B2 (en) * | 2011-09-30 | 2017-12-26 | University Of Louisville Research Foundation, Inc. | System and method for personalized dosing of pharmacologic agents |
CA2852536A1 (en) | 2011-10-24 | 2013-05-02 | Mannkind Corporation | Methods and compositions for treating pain |
US20150010527A1 (en) | 2012-02-01 | 2015-01-08 | Protalix Ltd. | Dnase i polypeptides, polynucleotides encoding same, methods of producing dnase i and uses thereof in therapy |
ES2624294T3 (es) | 2012-07-12 | 2017-07-13 | Mannkind Corporation | Sistemas de suministro de fármacos en polvo seco |
EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
EP2970149B1 (en) | 2013-03-15 | 2019-08-21 | MannKind Corporation | Microcrystalline diketopiperazine compositions and methods |
BR112016000937A8 (pt) | 2013-07-18 | 2021-06-22 | Mannkind Corp | formulações farmacêuticas de pó seco, método para a fabricação de uma formulação de pó seco e uso de uma formulação farmacêutica de pó seco |
CA2920488C (en) | 2013-08-05 | 2022-04-26 | Mannkind Corporation | Insufflation apparatus and methods |
WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
KR101494701B1 (ko) * | 2014-10-22 | 2015-02-26 | (주)메가메디칼 | 간접적으로 약액을 분무화하는 네블라이저 |
GB201501429D0 (en) * | 2015-01-28 | 2015-03-11 | British American Tobacco Co | Apparatus for heating aerosol generating material |
RU2721063C2 (ru) * | 2015-10-30 | 2020-05-15 | Джонсон энд Джонсон Консьюмер Инк. | Однодозовый асептический аэрозольный туманообразователь |
KR20240055129A (ko) * | 2016-01-11 | 2024-04-26 | 사이키 메디컬 엘티디. | 개인용 기화 장치 |
CN109475711B (zh) | 2016-05-19 | 2022-04-15 | 曼金德公司 | 用于检测和监控吸入的装置、系统和方法 |
WO2018071443A1 (en) | 2016-10-11 | 2018-04-19 | Microdose Therapeutx, Inc. | Inhaler and methods of use thereof |
WO2018071429A1 (en) * | 2016-10-11 | 2018-04-19 | Microdose Therapeutx, Inc. | Inhaler and methods of use thereof |
GB201700812D0 (en) | 2017-01-17 | 2017-03-01 | British American Tobacco Investments Ltd | Apparatus for heating smokable material |
JP7227163B2 (ja) | 2017-06-10 | 2023-02-21 | アイノビア,インコーポレイティド | 流体を取扱い、目に流体を送出するための方法および装置 |
WO2019191628A1 (en) * | 2018-03-30 | 2019-10-03 | Mariani Nick | Inhaler and method |
US20220168518A1 (en) * | 2019-02-27 | 2022-06-02 | NuvoAir AB | A method and a device for estimating an amount of a powder shaped material passing a bend in a flow channel |
BR112021021775A2 (pt) | 2019-04-29 | 2022-01-04 | Insmed Inc | Composições de pó seco de pró-fármacos de treprostinil e métodos de uso destas |
WO2023150747A1 (en) | 2022-02-07 | 2023-08-10 | Insmed Incorporated | Dry powder compositions of bedaquiline and salts and methods of use thereof |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH02257960A (ja) * | 1989-03-31 | 1990-10-18 | Nisshin Flour Milling Co Ltd | 薬の服用時間警報装置 |
GB8909891D0 (en) * | 1989-04-28 | 1989-06-14 | Riker Laboratories Inc | Device |
US5152456A (en) * | 1989-12-12 | 1992-10-06 | Bespak, Plc | Dispensing apparatus having a perforate outlet member and a vibrating device |
JPH0582489A (ja) * | 1991-09-20 | 1993-04-02 | Fujitsu Ltd | 半導体装置製造用反応装置 |
US6026809A (en) * | 1996-01-25 | 2000-02-22 | Microdose Technologies, Inc. | Inhalation device |
US5829436A (en) * | 1996-02-05 | 1998-11-03 | Aradigm Corporation | Ventilation imaging using a fine particle aerosol generator |
US5857456A (en) * | 1996-06-10 | 1999-01-12 | Sarnoff Corporation | Inhaler apparatus with an electronic means for enhanced release of dry powders |
EP0923957B1 (en) * | 1997-11-19 | 2001-10-31 | Microflow Engineering SA | Nozzle body and liquid droplet spray device for an inhaler suitable for respiratory therapies |
ES2253898T3 (es) * | 1998-06-12 | 2006-06-01 | Microdose Technologies Inc. | Dispositivo para la administracion de farmacos y medicamentos. |
-
2001
- 2001-01-24 AU AU2001231102A patent/AU2001231102B2/en not_active Expired
- 2001-01-24 PL PL358133A patent/PL201275B1/pl unknown
- 2001-01-24 AT AT01903260T patent/ATE366126T1/de not_active IP Right Cessation
- 2001-01-24 BR BR0109127-1A patent/BR0109127A/pt not_active IP Right Cessation
- 2001-01-24 MX MXPA02008605A patent/MXPA02008605A/es unknown
- 2001-01-24 KR KR1020027011799A patent/KR20020086624A/ko not_active Application Discontinuation
- 2001-01-24 CA CA002400349A patent/CA2400349C/en not_active Expired - Lifetime
- 2001-01-24 ES ES01903260T patent/ES2290110T3/es not_active Expired - Lifetime
- 2001-01-24 JP JP2001566730A patent/JP4934798B2/ja not_active Expired - Lifetime
- 2001-01-24 DE DE60129214T patent/DE60129214T2/de not_active Expired - Lifetime
- 2001-01-24 CN CNB018062601A patent/CN1179765C/zh not_active Expired - Fee Related
- 2001-01-24 EP EP01903260A patent/EP1267969B1/en not_active Expired - Lifetime
- 2001-01-24 AU AU3110201A patent/AU3110201A/xx active Pending
- 2001-01-24 WO PCT/US2001/002262 patent/WO2001068169A1/en active IP Right Grant
-
2002
- 2002-09-09 NO NO20024311A patent/NO20024311L/no unknown
-
2010
- 2010-10-13 JP JP2010230910A patent/JP2011056272A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ES2290110T3 (es) | 2008-02-16 |
DE60129214T2 (de) | 2008-04-10 |
NO20024311L (no) | 2002-11-11 |
NO20024311D0 (no) | 2002-09-09 |
DE60129214D1 (de) | 2007-08-16 |
CN1416357A (zh) | 2003-05-07 |
EP1267969B1 (en) | 2007-07-04 |
PL201275B1 (pl) | 2009-03-31 |
AU3110201A (en) | 2001-09-24 |
CA2400349A1 (en) | 2001-09-20 |
CN1179765C (zh) | 2004-12-15 |
AU2001231102B2 (en) | 2004-11-04 |
KR20020086624A (ko) | 2002-11-18 |
MXPA02008605A (es) | 2003-05-14 |
JP4934798B2 (ja) | 2012-05-16 |
EP1267969A1 (en) | 2003-01-02 |
EP1267969A4 (en) | 2004-12-08 |
JP2003526480A (ja) | 2003-09-09 |
WO2001068169A1 (en) | 2001-09-20 |
PL358133A1 (en) | 2004-08-09 |
JP2011056272A (ja) | 2011-03-24 |
ATE366126T1 (de) | 2007-07-15 |
CA2400349C (en) | 2009-11-10 |
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