BR0015149A - Método e composições para administração de taxanos oralmente a pacientes humanos - Google Patents
Método e composições para administração de taxanos oralmente a pacientes humanosInfo
- Publication number
- BR0015149A BR0015149A BR0015149-1A BR0015149A BR0015149A BR 0015149 A BR0015149 A BR 0015149A BR 0015149 A BR0015149 A BR 0015149A BR 0015149 A BR0015149 A BR 0015149A
- Authority
- BR
- Brazil
- Prior art keywords
- taxane
- human patients
- administered
- compositions
- orally
- Prior art date
Links
- 229940123237 Taxane Drugs 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 2
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 6
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 2
- 108010036949 Cyclosporine Proteins 0.000 abstract 2
- 206010020751 Hypersensitivity Diseases 0.000 abstract 2
- 229930105110 Cyclosporin A Natural products 0.000 abstract 1
- 229930012538 Paclitaxel Natural products 0.000 abstract 1
- 229940034982 antineoplastic agent Drugs 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229960001265 ciclosporin Drugs 0.000 abstract 1
- 229930182912 cyclosporin Natural products 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000009610 hypersensitivity Effects 0.000 abstract 1
- 229960001592 paclitaxel Drugs 0.000 abstract 1
- 238000009101 premedication Methods 0.000 abstract 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16231099P | 1999-10-27 | 1999-10-27 | |
| PCT/US2000/029633 WO2001030448A1 (en) | 1999-10-27 | 2000-10-27 | Method and compositions for administering taxanes orally to human patients |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0015149A true BR0015149A (pt) | 2002-10-29 |
Family
ID=22585092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0015149-1A BR0015149A (pt) | 1999-10-27 | 2000-10-27 | Método e composições para administração de taxanos oralmente a pacientes humanos |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1225956A1 (cs) |
| JP (1) | JP2003512443A (cs) |
| KR (1) | KR20030019296A (cs) |
| CN (1) | CN1450923A (cs) |
| AU (1) | AU1104201A (cs) |
| BR (1) | BR0015149A (cs) |
| CA (1) | CA2389583A1 (cs) |
| CO (1) | CO5251425A1 (cs) |
| CZ (1) | CZ20021484A3 (cs) |
| HU (1) | HUP0203303A3 (cs) |
| IL (1) | IL149360A0 (cs) |
| MX (1) | MXPA02004164A (cs) |
| NO (1) | NO20022008L (cs) |
| PL (1) | PL354777A1 (cs) |
| RU (1) | RU2002113659A (cs) |
| SK (1) | SK5822002A3 (cs) |
| WO (1) | WO2001030448A1 (cs) |
| ZA (1) | ZA200203358B (cs) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6750246B1 (en) | 2000-02-03 | 2004-06-15 | Bristol-Myers Squibb Company | C-4 carbonate taxanes |
| AU2002239282A1 (en) | 2000-11-28 | 2002-06-11 | Transform Pharmaceuticals, Inc. | Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof |
| US20040092428A1 (en) * | 2001-11-27 | 2004-05-13 | Hongming Chen | Oral pharmaceuticals formulation comprising paclitaxel, derivatives and methods of administration thereof |
| JP2006514698A (ja) * | 2002-10-30 | 2006-05-11 | スフェリックス， インコーポレイテッド | ナノ粒子生物活性物質 |
| US7659310B2 (en) | 2004-04-27 | 2010-02-09 | Formatech, Inc. | Methods of enhancing solubility of agents |
| US7345093B2 (en) | 2004-04-27 | 2008-03-18 | Formatech, Inc. | Methods of enhancing solubility of compounds |
| AR050043A1 (es) * | 2004-08-03 | 2006-09-20 | Novartis Ag | Metodos para mejorar la biodisponibilidad y composicion farmaceutica para trastornos cardiovasculares |
| CN101513395B (zh) * | 2008-02-20 | 2011-01-12 | 单宝华 | 紫杉醇类双层软胶囊口服制剂药物 |
| CA2781527C (en) | 2009-09-23 | 2017-10-24 | Indu Javeri | Methods for the preparation of liposomes |
| US10143652B2 (en) | 2009-09-23 | 2018-12-04 | Curirx Inc. | Methods for the preparation of liposomes |
| CA2798180A1 (en) | 2010-05-03 | 2011-11-10 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
| JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| JO3737B1 (ar) * | 2015-07-21 | 2021-01-31 | Athenex Therapeutics Ltd | تركيبات علاجية من باكليتاكسيل تعطى عن طريق الفم ومثبط P-gp لعلاج السرطان |
| CN112670147A (zh) * | 2019-10-15 | 2021-04-16 | 北京烁科中科信电子装备有限公司 | 一种利用多磁极磁棒间距控制的自动调节剂量均一性的方法 |
| EP4059497A1 (en) * | 2021-03-17 | 2022-09-21 | Dompé farmaceutici S.p.a. | C5ar1 inhibitors for treating hypersensitivity reactions to taxanes |
| CA3212816A1 (en) * | 2021-03-17 | 2022-09-22 | Dompe' Farmaceutici Spa | C5ar1 inhibitors for treating hypersensitivity reactions to taxanes |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6964946B1 (en) * | 1995-10-26 | 2005-11-15 | Baker Norton Pharmaceuticals, Inc. | Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same |
| US6245805B1 (en) * | 1995-10-26 | 2001-06-12 | Baker Norton Pharmaceuticals, Inc. | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
| EP0822815A4 (en) * | 1996-01-31 | 1998-04-01 | Bristol Myers Squibb Co | PROCESS FOR MAKING ORAL-LIKE TAXANES ACTIVE FROM THE PHARMACEUTICAL VIEW |
| CA2258556A1 (en) * | 1996-06-17 | 1997-12-24 | Julian Stanley Kroin | Drug resistance and multidrug resistance modulators |
| UA74767C2 (en) * | 1997-05-27 | 2006-02-15 | Baker Norton Pharma | Method and composition for oral use of taxanes in patients |
| GB9718903D0 (en) * | 1997-09-05 | 1997-11-12 | Glaxo Group Ltd | Method,compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
| AU756752B2 (en) * | 1998-04-01 | 2003-01-23 | Skyepharma Canada Inc. | Anticancer compositions |
| EP1178786A4 (en) * | 1999-05-21 | 2006-03-01 | American Bioscience Inc | PHARMACOLOGICALLY ACTIVE PROTEIN STABILIZING AGENTS; METHODS OF MANUFACTURE AND METHODS OF USE |
-
2000
- 2000-10-27 JP JP2001532859A patent/JP2003512443A/ja active Pending
- 2000-10-27 KR KR1020027005396A patent/KR20030019296A/ko not_active Withdrawn
- 2000-10-27 RU RU2002113659/15A patent/RU2002113659A/ru not_active Application Discontinuation
- 2000-10-27 PL PL00354777A patent/PL354777A1/xx not_active Application Discontinuation
- 2000-10-27 CN CN00815924A patent/CN1450923A/zh active Pending
- 2000-10-27 BR BR0015149-1A patent/BR0015149A/pt not_active IP Right Cessation
- 2000-10-27 CA CA002389583A patent/CA2389583A1/en not_active Abandoned
- 2000-10-27 HU HU0203303A patent/HUP0203303A3/hu unknown
- 2000-10-27 MX MXPA02004164A patent/MXPA02004164A/es unknown
- 2000-10-27 CO CO00082131A patent/CO5251425A1/es not_active Application Discontinuation
- 2000-10-27 SK SK582-2002A patent/SK5822002A3/sk unknown
- 2000-10-27 WO PCT/US2000/029633 patent/WO2001030448A1/en not_active Ceased
- 2000-10-27 IL IL14936000A patent/IL149360A0/xx unknown
- 2000-10-27 AU AU11042/01A patent/AU1104201A/en not_active Abandoned
- 2000-10-27 EP EP00972373A patent/EP1225956A1/en not_active Withdrawn
- 2000-10-27 CZ CZ20021484A patent/CZ20021484A3/cs unknown
-
2002
- 2002-04-26 ZA ZA200203358A patent/ZA200203358B/en unknown
- 2002-04-26 NO NO20022008A patent/NO20022008L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0203303A3 (en) | 2005-01-28 |
| HUP0203303A2 (hu) | 2003-02-28 |
| KR20030019296A (ko) | 2003-03-06 |
| NO20022008L (no) | 2002-06-19 |
| MXPA02004164A (es) | 2002-10-17 |
| EP1225956A1 (en) | 2002-07-31 |
| WO2001030448A1 (en) | 2001-05-03 |
| AU1104201A (en) | 2001-05-08 |
| ZA200203358B (en) | 2003-04-29 |
| NO20022008D0 (no) | 2002-04-26 |
| CA2389583A1 (en) | 2001-05-03 |
| JP2003512443A (ja) | 2003-04-02 |
| PL354777A1 (en) | 2004-02-23 |
| CO5251425A1 (es) | 2003-02-28 |
| RU2002113659A (ru) | 2004-01-27 |
| SK5822002A3 (en) | 2003-01-09 |
| IL149360A0 (en) | 2002-11-10 |
| CN1450923A (zh) | 2003-10-22 |
| CZ20021484A3 (cs) | 2003-12-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A,7A E 8A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008. |
|
| B15K | Others concerning applications: alteration of classification |
Ipc: A61K 47/42 (2006.01), A61P 35/00 (2006.01), A61K 3 |