BR0014758A - Sistemas e métodos para expressão de proteìna com alto rendimento - Google Patents
Sistemas e métodos para expressão de proteìna com alto rendimentoInfo
- Publication number
- BR0014758A BR0014758A BR0014758-3A BR0014758A BR0014758A BR 0014758 A BR0014758 A BR 0014758A BR 0014758 A BR0014758 A BR 0014758A BR 0014758 A BR0014758 A BR 0014758A
- Authority
- BR
- Brazil
- Prior art keywords
- systems
- methods
- high yield
- expressing protein
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Patente de Invenção: "SISTEMAS E MéTODOS PARA EXPRESSãO DE PROTEìNA COM ALTO RENDIMENTO". O aumento da atividade da piruvato carboxilase em vários sistemas de expressão de proteína resulta em rendimentos aumentados de proteína.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15946799P | 1999-10-13 | 1999-10-13 | |
PCT/US2000/028578 WO2001027258A2 (en) | 1999-10-13 | 2000-10-13 | High yield protein expression system and methods |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0014758A true BR0014758A (pt) | 2002-07-02 |
Family
ID=22572721
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0014758-3A BR0014758A (pt) | 1999-10-13 | 2000-10-13 | Sistemas e métodos para expressão de proteìna com alto rendimento |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1235903A2 (pt) |
JP (1) | JP2003511067A (pt) |
AR (1) | AR026892A1 (pt) |
AU (1) | AU1206801A (pt) |
BR (1) | BR0014758A (pt) |
CA (1) | CA2387605A1 (pt) |
HK (1) | HK1052198A1 (pt) |
MX (1) | MXPA02003634A (pt) |
WO (1) | WO2001027258A2 (pt) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7368266B2 (en) | 2001-02-13 | 2008-05-06 | Cj Corporation | Method for L-threonine production |
KR100397423B1 (ko) | 2001-02-13 | 2003-09-13 | 씨제이 주식회사 | L-쓰레오닌의 제조방법 |
US8119365B2 (en) | 2002-01-23 | 2012-02-21 | Wisconsin Alumni Research Foundation | Insertion sequence-free bacteria |
US8765408B2 (en) | 2002-01-23 | 2014-07-01 | Wisconsin Alumni Research Foundation | Prophage element-free bacteria |
US8039243B2 (en) | 2002-01-23 | 2011-10-18 | Wisconsin Alumni Research Foundation | Insertion sequence-free bacteria |
US6989265B2 (en) | 2002-01-23 | 2006-01-24 | Wisconsin Alumni Research Foundation | Bacteria with reduced genome |
DE10219714A1 (de) * | 2002-05-02 | 2003-11-27 | Holland Sweetener Co | Verfahren zur mikrobielien Herstellung von aromatischen Aminosäuren und anderen Metaboliten des aromatischen Aminosäurebiosyntheseweges |
US7303906B2 (en) | 2002-09-06 | 2007-12-04 | Wisconsin Alumni Research Foundation | Competent bacteria |
US9453251B2 (en) | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
KR101183720B1 (ko) | 2004-01-16 | 2012-09-17 | 다우 글로벌 테크놀로지스 엘엘씨 | 슈도모나스 플루오레센스에서의 포유류 단백질의 발현 |
WO2005087940A1 (en) * | 2004-03-11 | 2005-09-22 | Wisconsin Alumni Research Foundation | Genetically altered microorganisms with modified metabolism |
EP1584680A1 (en) * | 2004-04-08 | 2005-10-12 | Boehringer Ingelheim Austria GmbH | Fed-batch fermentation process for the production of plasmid DNA |
JP4720114B2 (ja) * | 2004-05-20 | 2011-07-13 | 三菱化学株式会社 | オキザロ酢酸またはオキザロ酢酸誘導体の製造方法 |
JP2008507294A (ja) | 2004-07-26 | 2008-03-13 | ダウ グローバル テクノロジーズ インコーポレイティド | 菌株遺伝子操作による改善されたタンパク質発現のための方法 |
US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
AU2008245696B2 (en) | 2007-04-27 | 2013-11-07 | Pelican Technology Holdings, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
EP2692911B1 (en) | 2011-03-31 | 2017-02-22 | Kunimine Industries Co., Ltd. | Use of agent for searching for protein crystallization conditions, and method for searching for protein crystallization conditions |
JP2015156844A (ja) * | 2014-02-25 | 2015-09-03 | 花王株式会社 | 枯草菌変異株及びそれを用いたジピコリン酸の製造方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995006114A1 (fr) * | 1993-08-24 | 1995-03-02 | Ajinomoto Co., Inc. | Allele de phosphenolpyruvate carboxylase, gene de cet allele et procede de production de l'acide amine |
EP2194122B1 (en) * | 1998-04-13 | 2015-12-02 | The University Of Georgia Research Foundation, Inc. | Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells |
DE19904794A1 (de) * | 1999-02-05 | 2000-08-10 | Biotechnolog Forschung Gmbh | Verfahren zur Verbesserung des Primärstoffwechsels von Säugerzelllinien |
-
2000
- 2000-10-13 AU AU12068/01A patent/AU1206801A/en not_active Abandoned
- 2000-10-13 AR ARP000105418A patent/AR026892A1/es not_active Application Discontinuation
- 2000-10-13 BR BR0014758-3A patent/BR0014758A/pt not_active IP Right Cessation
- 2000-10-13 JP JP2001530463A patent/JP2003511067A/ja active Pending
- 2000-10-13 CA CA002387605A patent/CA2387605A1/en not_active Abandoned
- 2000-10-13 WO PCT/US2000/028578 patent/WO2001027258A2/en not_active Application Discontinuation
- 2000-10-13 EP EP00973568A patent/EP1235903A2/en not_active Withdrawn
- 2000-10-13 MX MXPA02003634A patent/MXPA02003634A/es unknown
-
2003
- 2003-03-03 HK HK03101556.1A patent/HK1052198A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
WO2001027258A2 (en) | 2001-04-19 |
MXPA02003634A (es) | 2002-10-23 |
CA2387605A1 (en) | 2001-04-19 |
WO2001027258A3 (en) | 2001-12-27 |
JP2003511067A (ja) | 2003-03-25 |
EP1235903A2 (en) | 2002-09-04 |
AR026892A1 (es) | 2003-03-05 |
HK1052198A1 (zh) | 2003-09-05 |
AU1206801A (en) | 2001-04-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 5A, 6A, E 7A ANUIDADES. |
|
B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1929 DE 26/12/2007. |