BR0010707A - Métodos para purificação de proteìna usando extraçâo aquosa de duas fases - Google Patents
Métodos para purificação de proteìna usando extraçâo aquosa de duas fasesInfo
- Publication number
- BR0010707A BR0010707A BR0010707-7A BR0010707A BR0010707A BR 0010707 A BR0010707 A BR 0010707A BR 0010707 A BR0010707 A BR 0010707A BR 0010707 A BR0010707 A BR 0010707A
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- phase extraction
- aqueous
- protein purification
- growth hormone
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000000605 extraction Methods 0.000 title abstract 2
- 238000001742 protein purification Methods 0.000 title 1
- 229940122853 Growth hormone antagonist Drugs 0.000 abstract 1
- 102000002265 Human Growth Hormone Human genes 0.000 abstract 1
- 108010000521 Human Growth Hormone Proteins 0.000 abstract 1
- 239000000854 Human Growth Hormone Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"MéTODOS PARA PURIFICAçãO DE PROTEìNA USANDO EXTRAçãO AQUOSA DE DUAS FASES". Métodos são providos nesta invenção para o isolamento de hormónio de crescimento humano, hormónio de crescimento antagonista, ou um homólogo de ambos de fonte biológica. Os métodos da invenção usam extrações multifase.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/307,549 US6437101B1 (en) | 1999-05-07 | 1999-05-07 | Methods for protein purification using aqueous two-phase extraction |
PCT/US2000/012320 WO2000068260A1 (en) | 1999-05-07 | 2000-05-04 | Methods for protein purification using aqueous two-phase extraction |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0010707A true BR0010707A (pt) | 2002-06-04 |
Family
ID=23190235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0010707-7A BR0010707A (pt) | 1999-05-07 | 2000-05-04 | Métodos para purificação de proteìna usando extraçâo aquosa de duas fases |
Country Status (13)
Country | Link |
---|---|
US (1) | US6437101B1 (pt) |
EP (1) | EP1194445B1 (pt) |
JP (1) | JP2002544139A (pt) |
AT (1) | ATE384737T1 (pt) |
AU (1) | AU777974B2 (pt) |
BR (1) | BR0010707A (pt) |
CA (1) | CA2372513A1 (pt) |
DE (1) | DE60037886T2 (pt) |
ES (1) | ES2303507T3 (pt) |
IL (1) | IL146381A0 (pt) |
MX (1) | MXPA01011356A (pt) |
NZ (1) | NZ515381A (pt) |
WO (1) | WO2000068260A1 (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6966992B2 (en) * | 2001-03-19 | 2005-11-22 | Akzo Nobel Nv | Method of purification of molecules using unbranched terminal alkyldiols |
CN1688696A (zh) * | 2002-09-18 | 2005-10-26 | 蒙特利尔大学医疗中心 | Ghrh类似物 |
EP1609800B1 (de) * | 2004-06-25 | 2007-11-14 | Kühni Ag | Verfahren zur Extraktion von biologischem Material |
WO2006003134A1 (en) * | 2004-06-29 | 2006-01-12 | Ares Trading S.A. | Process for the purification of il-18 binding protein |
US20070048786A1 (en) * | 2005-09-01 | 2007-03-01 | Arnon Chait | Systems and methods for fractionation of protein mixtures |
US20080070230A1 (en) * | 2006-06-12 | 2008-03-20 | Wyeth | Methods for reducing or preventing liquid-liquid phase separation in high concentration protein solutions |
KR100836171B1 (ko) * | 2007-01-19 | 2008-06-09 | 인하대학교 산학협력단 | 분배 향상 물질이 접합된 생물물질을 이용한 수성이상계추출법에서의 친화성 분리 방법 |
DE102008013490A1 (de) * | 2008-03-10 | 2009-09-17 | Bayer Technology Services Gmbh | Verfahren zur Reinigung therapeutischer Proteine |
CN102224160A (zh) * | 2008-11-25 | 2011-10-19 | 通用电气健康护理生物科学股份公司 | 用于纯化治疗蛋白的水性两相萃取加强的沉淀方法 |
DE102011001743A1 (de) * | 2011-04-01 | 2012-10-04 | Technische Universität Dortmund | Verfahren zur Trennung/Reinigung von Biomolekühlen |
CN102662015B (zh) * | 2012-04-12 | 2013-11-20 | 湖南师范大学 | 基于无机盐促相变分离纳米金的生物样品的净化方法 |
US20130310554A1 (en) * | 2012-05-18 | 2013-11-21 | Hong Kong Baptist University | Aqueous Diphase Solvent System for Preparing High-Purity Polysaccharides |
CN111249531B (zh) * | 2020-01-19 | 2022-03-22 | 巴斯特医药科技(常州)有限公司 | 一种高活性植物酶制备胶原蛋白支架的方法 |
CN114957494A (zh) * | 2021-02-23 | 2022-08-30 | 江苏农牧科技职业学院 | 一种采用双水相萃取黄精多糖中蛋白质的工艺 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK144731C (da) | 1976-07-30 | 1982-10-18 | Nordisk Insulinlab | Fremgangsmaade til isolering af proteinhormoner stammende fra humant hypofysevaev |
JPS5815989A (ja) * | 1981-06-12 | 1983-01-29 | Sanki Eng Kk | 生理活性蛋白質の精製方法 |
DE3908422A1 (de) * | 1989-03-15 | 1990-09-20 | Forschungszentrum Juelich Gmbh | Verfahren zur extraktion von proteinen aus waessrigen biomassesuspensionen |
US5151358A (en) | 1989-06-13 | 1992-09-29 | Genencor International, Inc. | Processes for the recovery of naturally produced chymosin |
US5139943A (en) * | 1989-06-13 | 1992-08-18 | Genencor International, Inc. | Processes for the recovery of microbially produced chymosin |
US5182369A (en) | 1990-02-28 | 1993-01-26 | Monsanto Company | Method for purifying somatotropin monomers |
US5328841A (en) * | 1990-10-05 | 1994-07-12 | Genencor International, Inc. | Methods for isolating EG III cellulase component and EG III cellulase in polyethylene glycol using inorganic salt and polyethylene glycol |
SE9003534D0 (sv) * | 1990-11-06 | 1990-11-06 | Kabigen Ab | A method for isolating and purifying peptides and proteins |
US5407810A (en) | 1993-08-20 | 1995-04-18 | Genentech, Inc. | Aqueous multiple-phase isolation of polypeptide |
US5734024A (en) * | 1996-04-19 | 1998-03-31 | Boris Y. Zaslavsky | Method for determining the biological activity of recombinant human growth hormone |
GB0205898D0 (en) * | 2002-03-13 | 2002-04-24 | Pharmacia Ab | Treatment of type I diabetes mellitus |
-
1999
- 1999-05-07 US US09/307,549 patent/US6437101B1/en not_active Expired - Lifetime
-
2000
- 2000-05-04 CA CA002372513A patent/CA2372513A1/en not_active Abandoned
- 2000-05-04 WO PCT/US2000/012320 patent/WO2000068260A1/en active Search and Examination
- 2000-05-04 EP EP00928866A patent/EP1194445B1/en not_active Expired - Lifetime
- 2000-05-04 AT AT00928866T patent/ATE384737T1/de not_active IP Right Cessation
- 2000-05-04 DE DE60037886T patent/DE60037886T2/de not_active Expired - Fee Related
- 2000-05-04 IL IL14638100A patent/IL146381A0/xx unknown
- 2000-05-04 BR BR0010707-7A patent/BR0010707A/pt not_active IP Right Cessation
- 2000-05-04 JP JP2000616234A patent/JP2002544139A/ja not_active Withdrawn
- 2000-05-04 NZ NZ515381A patent/NZ515381A/en unknown
- 2000-05-04 AU AU47036/00A patent/AU777974B2/en not_active Ceased
- 2000-05-04 MX MXPA01011356A patent/MXPA01011356A/es active IP Right Grant
- 2000-05-04 ES ES00928866T patent/ES2303507T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6437101B1 (en) | 2002-08-20 |
NZ515381A (en) | 2003-10-31 |
IL146381A0 (en) | 2002-07-25 |
ATE384737T1 (de) | 2008-02-15 |
EP1194445A1 (en) | 2002-04-10 |
DE60037886D1 (de) | 2008-03-13 |
WO2000068260A1 (en) | 2000-11-16 |
EP1194445A4 (en) | 2002-10-09 |
EP1194445B1 (en) | 2008-01-23 |
AU4703600A (en) | 2000-11-21 |
JP2002544139A (ja) | 2002-12-24 |
MXPA01011356A (es) | 2003-08-20 |
ES2303507T3 (es) | 2008-08-16 |
AU777974B2 (en) | 2004-11-04 |
CA2372513A1 (en) | 2000-11-16 |
DE60037886T2 (de) | 2009-01-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 9A. E 10A. ANUIDADE(S). |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2077 DE 26/10/2010. |