BR0008322A - Implante - Google Patents

Implante

Info

Publication number
BR0008322A
BR0008322A BR0008322-4A BR0008322A BR0008322A BR 0008322 A BR0008322 A BR 0008322A BR 0008322 A BR0008322 A BR 0008322A BR 0008322 A BR0008322 A BR 0008322A
Authority
BR
Brazil
Prior art keywords
implant
suggested
diffusion
receptacle space
pore
Prior art date
Application number
BR0008322-4A
Other languages
English (en)
Inventor
Wolfgang Brandau
Alfons Fischer
Thomas Sawitowski
Guenter Schmid
Original Assignee
Alcove Surfaces Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19910188A external-priority patent/DE19910188C2/de
Application filed by Alcove Surfaces Gmbh filed Critical Alcove Surfaces Gmbh
Publication of BR0008322A publication Critical patent/BR0008322A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1002Intraluminal radiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Prostheses (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)

Abstract

Patente de Invenção: "IMPLANTE". A presente invenção trata de um implante dotado de um espaço de receptáculo para um agente terapêutico, que pode deixar o espaço de receptáculo através do elemento permeável. Para a dosagem exata, um elemento de difusão de poro aberto é sugerido como o elemento permeável, onde as paredes dos poros são quimicamente modificadas para controlar a difusão.
BR0008322-4A 1999-02-18 2000-02-17 Implante BR0008322A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19907006 1999-02-18
DE19910188A DE19910188C2 (de) 1998-11-02 1999-03-09 Implantat, Verfahren zu seiner Herstellung und seine Verwendung
DE19948783A DE19948783C2 (de) 1999-02-18 1999-10-08 Implantat
PCT/EP2000/001287 WO2000048660A1 (de) 1999-02-18 2000-02-17 Implantat

Publications (1)

Publication Number Publication Date
BR0008322A true BR0008322A (pt) 2002-01-29

Family

ID=27218985

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008322-4A BR0008322A (pt) 1999-02-18 2000-02-17 Implante

Country Status (20)

Country Link
US (1) US6740077B1 (pt)
EP (1) EP1150738B1 (pt)
JP (1) JP2002537029A (pt)
CN (1) CN1186105C (pt)
AT (1) ATE227597T1 (pt)
AU (1) AU761882B2 (pt)
BR (1) BR0008322A (pt)
CA (1) CA2371800A1 (pt)
DE (2) DE19948783C2 (pt)
DK (1) DK1150738T3 (pt)
EE (1) EE200100435A (pt)
ES (1) ES2183788T3 (pt)
IL (1) IL144753A0 (pt)
NO (1) NO20013917L (pt)
NZ (1) NZ513364A (pt)
PL (1) PL350562A1 (pt)
PT (1) PT1150738E (pt)
TR (1) TR200102384T2 (pt)
WO (1) WO2000048660A1 (pt)
YU (1) YU58801A (pt)

Families Citing this family (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7713297B2 (en) 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US7018401B1 (en) 1999-02-01 2006-03-28 Board Of Regents, The University Of Texas System Woven intravascular devices and methods for making the same and apparatus for delivery of the same
CA2434156A1 (en) 2000-12-29 2002-07-25 Bausch & Lomb Incorporated Sustained release drug delivery devices
US6756058B2 (en) 2001-01-03 2004-06-29 Bausch & Lomb Incorporated Sustained release drug delivery devices with multiple agents
DE10123442C2 (de) * 2001-03-23 2003-05-22 Alcove Surfaces Gmbh Operationswerkzeug
US6697662B2 (en) 2001-03-23 2004-02-24 Alcover Surfaces Gmbh Surgical instrument
DE60239868D1 (de) 2001-06-12 2011-06-09 Univ Johns Hopkins Med Reservoirvorrichtung für die intraokulare arzneimittelabgabe
WO2003002243A2 (en) 2001-06-27 2003-01-09 Remon Medical Technologies Ltd. Method and device for electrochemical formation of therapeutic species in vivo
KR101191254B1 (ko) * 2002-03-11 2012-10-16 알콘, 인코퍼레이티드 이식 가능한 약물 전달 시스템
JP2006514848A (ja) 2002-11-13 2006-05-18 セタゴン インコーポレーティッド 多孔質層を有する医療装置およびその作製方法
US9770349B2 (en) 2002-11-13 2017-09-26 University Of Virginia Patent Foundation Nanoporous stents with enhanced cellular adhesion and reduced neointimal formation
US20060121080A1 (en) 2002-11-13 2006-06-08 Lye Whye K Medical devices having nanoporous layers and methods for making the same
AU2003270244A1 (en) 2002-11-14 2004-06-03 Universitat Duisburg-Essen Implant, therapeutic agent and micelle
US7488343B2 (en) 2003-09-16 2009-02-10 Boston Scientific Scimed, Inc. Medical devices
US20050158365A1 (en) * 2003-12-22 2005-07-21 David Watson Drug delivery device with mechanical locking mechanism
US8137397B2 (en) 2004-02-26 2012-03-20 Boston Scientific Scimed, Inc. Medical devices
NL1025624C2 (nl) * 2004-03-03 2005-09-07 Solvist Stroomrestrictie.
US8348930B2 (en) * 2005-07-01 2013-01-08 Microlin, Llc Fluid delivery device with a diffusion membrane and electrochemical pump
GB2442396B (en) * 2005-07-22 2011-05-11 Univ Utah Res Found Osmotically driven dispense pump and related components for use in high pressure applications
US20070212397A1 (en) * 2005-09-15 2007-09-13 Roth Daniel B Pharmaceutical delivery device and method for providing ocular treatment
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8089029B2 (en) 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US20070224235A1 (en) 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8187620B2 (en) 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
JP2009540926A (ja) * 2006-06-22 2009-11-26 ウィルソン−クック・メディカル・インコーポレーテッド 自浄式ステント
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
EP2032091A2 (en) 2006-06-29 2009-03-11 Boston Scientific Limited Medical devices with selective coating
JP2009545407A (ja) 2006-08-02 2009-12-24 ボストン サイエンティフィック サイムド,インコーポレイテッド 三次元分解制御を備えたエンドプロテーゼ
EP1891995A1 (en) * 2006-08-08 2008-02-27 Debiotech S.A. Drug loading of porous coating
ATE508708T1 (de) 2006-09-14 2011-05-15 Boston Scient Ltd Medizinprodukte mit wirkstofffreisetzender beschichtung
EP2081616B1 (en) 2006-09-15 2017-11-01 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8057534B2 (en) 2006-09-15 2011-11-15 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US7955382B2 (en) 2006-09-15 2011-06-07 Boston Scientific Scimed, Inc. Endoprosthesis with adjustable surface features
EP2068964B1 (en) 2006-09-15 2017-11-01 Boston Scientific Limited Medical devices and methods of making the same
JP2010503491A (ja) 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド 生物学的安定性無機層を有する生浸食性エンドプロスシーシス
EP2068962B1 (en) 2006-09-18 2013-01-30 Boston Scientific Limited Endoprostheses
CN102525700B (zh) 2006-10-22 2015-05-13 Idev科技公司 支架推进装置
KR101659197B1 (ko) 2006-10-22 2016-09-22 이데브 테크놀로지스, 아이엔씨. 스텐트 전진을 위한 장치 및 방법
US7981150B2 (en) 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
ES2356274T3 (es) 2006-12-28 2011-04-06 Boston Scientific Limited Endoprótesis biodegradables y procedimientos de fabricación de las mismas.
US20080208308A1 (en) * 2007-02-27 2008-08-28 Medtronic Vascular, Inc. High Temperature Oxidation-Reduction Process to Form Porous Structures on a Medical Implant
US8070797B2 (en) 2007-03-01 2011-12-06 Boston Scientific Scimed, Inc. Medical device with a porous surface for delivery of a therapeutic agent
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
EP1977754A1 (en) * 2007-04-02 2008-10-08 Universität Duisburg-Essen Treatment of diseases with nanoparticles having a size-dependent cytotoxicity
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
US7976915B2 (en) 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
US8002823B2 (en) 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7942926B2 (en) 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
US9284409B2 (en) 2007-07-19 2016-03-15 Boston Scientific Scimed, Inc. Endoprosthesis having a non-fouling surface
US8815273B2 (en) 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
WO2009018340A2 (en) 2007-07-31 2009-02-05 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
EP2185103B1 (en) 2007-08-03 2014-02-12 Boston Scientific Scimed, Inc. Coating for medical device having increased surface area
US8052745B2 (en) 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US7938855B2 (en) 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
US8216632B2 (en) 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8029554B2 (en) 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
EP2271380B1 (en) 2008-04-22 2013-03-20 Boston Scientific Scimed, Inc. Medical devices having a coating of inorganic material
US8932346B2 (en) 2008-04-24 2015-01-13 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
EP2303350A2 (en) 2008-06-18 2011-04-06 Boston Scientific Scimed, Inc. Endoprosthesis coating
JP5670326B2 (ja) * 2008-06-25 2015-02-18 メディメトリクス ペルソナリズド ドルグ デリヴェリー ベー ヴェ 複数の薬剤リザーバを有する電子ピル
CA2728668A1 (en) 2008-06-25 2009-12-30 Boston Scientific Scimed, Inc. Medical devices containing therapeutic agents
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
US8231980B2 (en) 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
EP2391419B1 (en) 2009-01-29 2019-06-12 ForSight Vision4, Inc. Posterior segment drug delivery
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
US8734829B2 (en) * 2009-02-13 2014-05-27 Boston Scientific Scimed, Inc. Medical devices having polymeric nanoporous coatings for controlled therapeutic agent delivery and a nonpolymeric macroporous protective layer
WO2010101901A2 (en) 2009-03-02 2010-09-10 Boston Scientific Scimed, Inc. Self-buffering medical implants
US8071156B2 (en) 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
US20100256772A1 (en) * 2009-04-02 2010-10-07 Wilson-Cook Medical Inc. System and method for maintaining patency of a stent using a magnet
US8287937B2 (en) 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese
SG177768A1 (en) * 2009-08-25 2012-03-29 Prostec Co Ltd Medical supplies and method of producing the same
US8668732B2 (en) 2010-03-23 2014-03-11 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US9023095B2 (en) 2010-05-27 2015-05-05 Idev Technologies, Inc. Stent delivery system with pusher assembly
CN103153316B (zh) 2010-08-05 2015-08-19 弗赛特影像4股份有限公司 组合药物递送方法和设备
US9033911B2 (en) 2010-08-05 2015-05-19 Forsight Vision4, Inc. Injector apparatus and method for drug delivery
WO2012019176A2 (en) 2010-08-05 2012-02-09 Forsight Vision4 Inc. Implantable therapeutic device
AU2011329656B2 (en) 2010-11-19 2017-01-05 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
EP2726016B1 (en) 2011-06-28 2023-07-19 ForSight Vision4, Inc. An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye
EP2739252A4 (en) 2011-08-05 2015-08-12 Forsight Vision4 Inc SMALL MOLECULE ADMINISTRATION USING AN IMPLANTABLE THERAPEUTIC DEVICE
CA2848385C (en) 2011-09-16 2021-10-26 Forsight Vision4, Inc. Methods and apparatus to exchange a fluid of an implantable device
WO2013116061A1 (en) 2012-02-03 2013-08-08 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
AU2014236455B2 (en) 2013-03-14 2018-07-12 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
JP6385423B2 (ja) 2013-03-28 2018-09-05 フォーサイト・ビジョン フォー・インコーポレーテッド 治療物質送達用の眼移植片
TWI551313B (zh) * 2013-05-24 2016-10-01 中臺科技大學 胰島素注射裝置
RU2695563C2 (ru) 2014-07-15 2019-07-24 Форсайт Вижн4, Инк. Способ и устройство для доставки глазного имплантата
BR112017002466A2 (pt) 2014-08-08 2017-12-05 Forsight Vision4 Inc formulações estáveis e solúveis de inibidores da tirosina cinase do receptor, e métodos para a sua preparação
WO2016077371A1 (en) 2014-11-10 2016-05-19 Forsight Vision4, Inc. Expandable drug delivery devices and method of use
EP3377009B1 (en) 2015-11-20 2020-10-28 ForSight Vision4, Inc. Porous structures for extended release drug delivery devices
US11617680B2 (en) 2016-04-05 2023-04-04 Forsight Vision4, Inc. Implantable ocular drug delivery devices
CN115607358A (zh) 2017-11-21 2023-01-17 弗赛特影像4股份有限公司 用于可扩展端口递送系统的流体交换装置及使用方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732865A (en) * 1971-01-13 1973-05-15 Alza Corp Osmotic dispenser
US3760804A (en) * 1971-01-13 1973-09-25 Alza Corp Improved osmotic dispenser employing magnesium sulphate and magnesium chloride
CH580961A5 (en) * 1972-01-13 1976-10-29 Alza Corp Dispenser - functioning by osmotic pressure using active agents in solid or semi solid form
US3929132A (en) * 1973-04-10 1975-12-30 Alza Corp Osmotic dispenser
US3944064A (en) 1973-10-26 1976-03-16 Alza Corporation Self-monitored device for releasing agent at functional rate
US3946734A (en) * 1975-02-19 1976-03-30 The United States Of America As Represented By The Secretary Of State Apparatus for controlling the release of a drug
US4218255A (en) 1976-08-30 1980-08-19 University Of Dayton Porous ceramic carriers for controlled release of proteins, polypeptide hormones, and other substances within human and/or other mamillian species and method
US5082668A (en) * 1983-05-11 1992-01-21 Alza Corporation Controlled-release system with constant pushing source
US5000957A (en) * 1984-03-19 1991-03-19 Alza Corporation Dispenser comprising hydrophilic osmopolymer
US5008112A (en) * 1985-12-16 1991-04-16 International Minerals & Chem. Corporation Device for the extended delivery of diffusible agents
US5062841A (en) * 1988-08-12 1991-11-05 The Regents Of The University Of California Implantable, self-regulating mechanochemical insulin pump
US5034229A (en) * 1988-12-13 1991-07-23 Alza Corporation Dispenser for increasing feed conversion of hog
US5769823A (en) 1995-03-23 1998-06-23 Tricumed Gmbh Implantable infusion pump
US5908414A (en) 1995-05-03 1999-06-01 Tricumed Gmbh Implantable infusion pump
DE19704497C1 (de) 1997-02-06 1997-11-20 Tricumed Gmbh Implantierbare Infusionspumpe
US5843172A (en) 1997-04-15 1998-12-01 Advanced Cardiovascular Systems, Inc. Porous medicated stent
US5897528A (en) * 1998-04-30 1999-04-27 Medtronic, Inc. Filtered intracerebroventricular or intraspinal access port with direct cerebrospinal fluid access

Also Published As

Publication number Publication date
PT1150738E (pt) 2003-03-31
TR200102384T2 (tr) 2002-01-21
ES2183788T3 (es) 2003-04-01
AU761882B2 (en) 2003-06-12
DK1150738T3 (da) 2002-12-30
CA2371800A1 (en) 2000-08-24
NO20013917D0 (no) 2001-08-10
NO20013917L (no) 2001-08-10
IL144753A0 (en) 2002-06-30
EP1150738B1 (de) 2002-11-13
CN1339976A (zh) 2002-03-13
DE19948783C2 (de) 2001-06-13
YU58801A (sh) 2004-03-12
EP1150738A1 (de) 2001-11-07
DE19948783A1 (de) 2000-08-24
ATE227597T1 (de) 2002-11-15
DE50000750D1 (de) 2002-12-19
US6740077B1 (en) 2004-05-25
NZ513364A (en) 2003-10-31
PL350562A1 (en) 2002-12-16
AU3156100A (en) 2000-09-04
JP2002537029A (ja) 2002-11-05
EE200100435A (et) 2002-12-16
WO2000048660A1 (de) 2000-08-24
CN1186105C (zh) 2005-01-26

Similar Documents

Publication Publication Date Title
DE50000750D1 (de) Implantat
DE60031248D1 (de) Elektroaktive pore
MXPA03007140A (es) Derivados de carbolina.
BRPI0010891B8 (pt) geração de microespuma terapêutica.
DK1459749T3 (da) (S,S)-reboxetin til behandling af inkontinens
MXPA03002911A (es) Compuestos quimicos.
MXPA02012076A (es) Compuestos quimicos.
MXPA02012659A (es) Derivados de pirazindiona condensados.
ES2160410T3 (es) Preparados de complejos de protrombina inmunotolerantes.
TR200103119T2 (tr) Göz kurumasının tedavisi için madde.
CY1105142T1 (el) Χρηση υποκατεστημενων ενωσεων 6-διμεθυλαμινομεθυλο-1-φαινυλο-κυκλοεξανιου για τη θepαπεια της ακρατειας ουρων
PT1435991E (pt) Utilização de aplidina para o tratamento de cancro pancreático
IT1317070B1 (it) Pilastro di guarigione per immobilizzazione intrachirurgica diimpianti dentali per carico immediato.
MXPA02012472A (es) Compuestos quimicos.
ATE323493T1 (de) Gesteuerte freisetzung von antidepressiva
ATE319455T1 (de) Vitamin d-verbindungen zur behandlung von chronischer tranplantatnephropathie bei nieren transplantieren patienten
SV2001000570A (es) Agente terapeutico cristalino ref. pcs22011afae/bb
DE60135675D1 (de) Behandlung von motorischen veränderungen mit 5-hydrxoytryptamin 1a rezeptor aktivität verstärkenden wirkstoffen
IS5231A (is) Vefjaþáttur sem hefur áhrif á blóðæðarmyndun
MY131858A (en) Active ingredient combination for the pharmacological therapy of nicotine dependence
ITTO20011197A0 (it) Corpo cilindrico ornamentale.
ITMI20041822A1 (it) "agente terapeutico utile per il trattamento di neoplasie plasmacellulari"
UA36367A (uk) Кальцію сукцинат, що має кардіотонічну дію
SE9802075D0 (sv) New use
MXPA04003673A (es) Uso de aplidina para el tratamiento de cancer pancreatico.

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A, 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1925 DE 27/11/2007.