BG99545A - Method for the preparation of dihydroartemisininsemisuccinate - Google Patents

Method for the preparation of dihydroartemisininsemisuccinate

Info

Publication number
BG99545A
BG99545A BG99545A BG9954595A BG99545A BG 99545 A BG99545 A BG 99545A BG 99545 A BG99545 A BG 99545A BG 9954595 A BG9954595 A BG 9954595A BG 99545 A BG99545 A BG 99545A
Authority
BG
Bulgaria
Prior art keywords
dihydroartemisininsemisuccinate
mol equivalents
preparation
theacylation
onetri
Prior art date
Application number
BG99545A
Other languages
Bulgarian (bg)
English (en)
Inventor
����� �. �������
Rolph Haenni
Original Assignee
Институт по органична химия с център по фитохимия при БАН
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Институт по органична химия с център по фитохимия при БАН filed Critical Институт по органична химия с център по фитохимия при БАН
Priority to BG99545A priority Critical patent/BG99545A/xx
Priority to JP8064396A priority patent/JPH08283269A/ja
Priority to US08/624,744 priority patent/US5654446A/en
Priority to DE59600791T priority patent/DE59600791D1/de
Priority to ZA962538A priority patent/ZA962538B/xx
Priority to EP96810198A priority patent/EP0736535B1/de
Publication of BG99545A publication Critical patent/BG99545A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BG99545A 1995-04-03 1995-04-03 Method for the preparation of dihydroartemisininsemisuccinate BG99545A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
BG99545A BG99545A (en) 1995-04-03 1995-04-03 Method for the preparation of dihydroartemisininsemisuccinate
JP8064396A JPH08283269A (ja) 1995-04-03 1996-03-21 ジヒドロアルテミシニンヘミスクシネートの製法
US08/624,744 US5654446A (en) 1995-04-03 1996-03-27 Process for the preparation of dihydroartemisinin hemisuccinate
DE59600791T DE59600791D1 (de) 1995-04-03 1996-03-29 Verfahren zur Herstellung von Dihydroartemisinin-hemisuccinat
ZA962538A ZA962538B (en) 1995-04-03 1996-03-29 Process for the preparation of dihydroartemisinin hemisucinate
EP96810198A EP0736535B1 (de) 1995-04-03 1996-03-29 Verfahren zur Herstellung von Dihydroartemisinin-hemisuccinat

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BG99545A BG99545A (en) 1995-04-03 1995-04-03 Method for the preparation of dihydroartemisininsemisuccinate

Publications (1)

Publication Number Publication Date
BG99545A true BG99545A (en) 1998-09-30

Family

ID=3926079

Family Applications (1)

Application Number Title Priority Date Filing Date
BG99545A BG99545A (en) 1995-04-03 1995-04-03 Method for the preparation of dihydroartemisininsemisuccinate

Country Status (6)

Country Link
US (1) US5654446A (ja)
EP (1) EP0736535B1 (ja)
JP (1) JPH08283269A (ja)
BG (1) BG99545A (ja)
DE (1) DE59600791D1 (ja)
ZA (1) ZA962538B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060270863A1 (en) * 2005-05-27 2006-11-30 Amyris Biotechnologies Conversion of amorpha-4,11-diene to artemisinin and artemisinin precursors
CN102812015B (zh) * 2010-03-11 2015-07-15 学校法人早稻田大学 来自腔肠动物的抗原虫化合物
CN102304136A (zh) * 2010-07-10 2012-01-04 恩施济源药业科技开发有限公司 一种蒿甲醚的生产方法
CN102304137A (zh) * 2010-08-09 2012-01-04 恩施济源药业科技开发有限公司 一种青蒿琥酯的生产方法
CN102304138A (zh) * 2010-08-09 2012-01-04 恩施济源药业科技开发有限公司 一种青蒿琥酯母液的处理方法
US9271620B2 (en) 2012-03-27 2016-03-01 Daryl S. Meredith Vacuum
CN103483350A (zh) * 2013-06-25 2014-01-01 重庆华方武陵山制药有限公司 青蒿素的超声回流提取工艺
CN103374016B (zh) * 2013-07-25 2016-08-10 重庆恒星生物技术有限责任公司 一种青蒿琥酯纯化工艺
CN103524527B (zh) * 2013-10-25 2015-09-16 广州合诚三先生物科技有限公司 一种从青蒿素分离后废液中同时提取青蒿酸和二氢青蒿酸的方法

Also Published As

Publication number Publication date
DE59600791D1 (de) 1998-12-17
US5654446A (en) 1997-08-05
JPH08283269A (ja) 1996-10-29
EP0736535A1 (de) 1996-10-09
ZA962538B (en) 1996-11-01
EP0736535B1 (de) 1998-11-11

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