BG62700B1 - Молекули на рекомбинантна дезоксирибонуклеинова киселина (днк), кодиращи ензими аминопептидаза,и приложението им за получаването на ваксини против хелминтни инфекции - Google Patents

Молекули на рекомбинантна дезоксирибонуклеинова киселина (днк), кодиращи ензими аминопептидаза,и приложението им за получаването на ваксини против хелминтни инфекции Download PDF

Info

Publication number
BG62700B1
BG62700B1 BG99246A BG9924694A BG62700B1 BG 62700 B1 BG62700 B1 BG 62700B1 BG 99246 A BG99246 A BG 99246A BG 9924694 A BG9924694 A BG 9924694A BG 62700 B1 BG62700 B1 BG 62700B1
Authority
BG
Bulgaria
Prior art keywords
sequences
h11od
nucleic acid
dna
seq
Prior art date
Application number
BG99246A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG99246A (bg
Inventor
Margaret Graham
Trevor Smith
Edward Munn
David Knox
Joanna Oliver
Susan Newton
Original Assignee
The Biotechnology And Biological Sciences Researchcouncil
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Biotechnology And Biological Sciences Researchcouncil filed Critical The Biotechnology And Biological Sciences Researchcouncil
Publication of BG99246A publication Critical patent/BG99246A/bg
Publication of BG62700B1 publication Critical patent/BG62700B1/bg

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0003Invertebrate antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • C07K14/4354Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms from nematodes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
BG99246A 1992-05-08 1994-12-08 Молекули на рекомбинантна дезоксирибонуклеинова киселина (днк), кодиращи ензими аминопептидаза,и приложението им за получаването на ваксини против хелминтни инфекции BG62700B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929209993A GB9209993D0 (en) 1992-05-08 1992-05-08 Vaccines
PCT/GB1993/000943 WO1993023542A1 (en) 1992-05-08 1993-05-07 Recombinant dna molecules encoding aminopeptidase enzymes and their use in the preparation of vaccines against helminth infections

Publications (2)

Publication Number Publication Date
BG99246A BG99246A (bg) 1995-07-28
BG62700B1 true BG62700B1 (bg) 2000-05-31

Family

ID=10715227

Family Applications (1)

Application Number Title Priority Date Filing Date
BG99246A BG62700B1 (bg) 1992-05-08 1994-12-08 Молекули на рекомбинантна дезоксирибонуклеинова киселина (днк), кодиращи ензими аминопептидаза,и приложението им за получаването на ваксини против хелминтни инфекции

Country Status (25)

Country Link
US (4) US6066503A (fi)
EP (1) EP0640133B1 (fi)
JP (1) JPH07508879A (fi)
CN (1) CN1053699C (fi)
AT (1) ATE195346T1 (fi)
AU (1) AU677582B2 (fi)
BG (1) BG62700B1 (fi)
CA (1) CA2134326A1 (fi)
CZ (1) CZ274494A3 (fi)
DE (1) DE69329195T2 (fi)
DK (1) DK0640133T3 (fi)
ES (1) ES2151506T3 (fi)
FI (1) FI945221A0 (fi)
GB (1) GB9209993D0 (fi)
GR (1) GR3034766T3 (fi)
HU (1) HU218041B (fi)
NO (1) NO944245L (fi)
NZ (1) NZ252221A (fi)
PL (1) PL175900B1 (fi)
PT (1) PT640133E (fi)
RO (1) RO117709B1 (fi)
RU (1) RU2140986C1 (fi)
SK (1) SK132394A3 (fi)
WO (1) WO1993023542A1 (fi)
ZA (1) ZA933216B (fi)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6099843A (en) * 1991-02-12 2000-08-08 Heska Corporation Parasitic helminth PLA2 proteins
US6156556A (en) * 1991-12-13 2000-12-05 Heska Corporation Flea protease proteins, nucleic acid molecules, and uses thereof
US5972645A (en) * 1991-12-13 1999-10-26 Heska Corporation Flea serine protease nucleic acid molecules
US6210920B1 (en) 1991-12-13 2001-04-03 Heska Corporation Flea protease proteins, nucleic acid molecules, and uses thereof
US6121035A (en) * 1991-12-13 2000-09-19 Heska Corporation Flea aminopeptidase proteins and uses thereof
US6150125A (en) * 1991-12-13 2000-11-21 Heska Corporation Flea protease proteins and uses thereof
US6146870A (en) * 1991-12-13 2000-11-14 Heska Corporation Flea protease proteins
GB9209993D0 (en) * 1992-05-08 1992-06-24 Munn Edward A Vaccines
GB9302302D0 (en) * 1993-02-05 1993-03-24 Pitman Moore Inc Process
GB9303681D0 (en) * 1993-02-24 1993-04-14 Pitman Moore Inc Vaccines
GB9322702D0 (en) 1993-11-03 1993-12-22 Agricultural & Food Res Vaccines
BR9305075A (pt) * 1993-12-16 1995-08-08 Fundacao Oswaldo Cruz Antígeno para conferir imunidade protetora contra infecções helmínticas em humanos e animais,e processo de vacinação para aplicação na imunoprofilaxia de doenças helmintológicas de interesse veterinário e médico
US6214579B1 (en) 1994-10-18 2001-04-10 Heska Corporation Flea leucine aminopeptidase nucleic acid molecules and uses thereof
US6204010B1 (en) 1995-06-07 2001-03-20 Heska Corporation Flea protease proteins, nucleic acid molecules, and uses thereof
US6139840A (en) * 1995-10-18 2000-10-31 Heska Corporation Methods of eliciting an antibody response using flea protease proteins and homologs thereof
IL120704A0 (en) * 1996-04-24 1998-04-05 Heska Corp Flea protease proteins nucleic acid molecules and uses thereof
US20040006204A1 (en) 2002-04-02 2004-01-08 Miriam Tendler Synthetic active peptide fragments
US7951557B2 (en) 2003-04-27 2011-05-31 Protalix Ltd. Human lysosomal proteins from plant cell culture
RU2468076C2 (ru) 2007-05-07 2012-11-27 Проталикс Лтд. Одноразовое устройство для культивирования и сбора растительной ткани и/или клеток, способ и система культивирования и сбора растительной ткани и/или растительных клеток
US20080294361A1 (en) * 2007-05-24 2008-11-27 Popp Shane M Intelligent execution system for the monitoring and execution of vaccine manufacturing
ES2325243B1 (es) 2008-02-27 2011-05-04 Universidad De Granada Antigeno recombinante.
US9052304B2 (en) 2009-03-13 2015-06-09 Terrasep, Llc Methods and apparatus for centrifugal liquid chromatography
CN112961848B (zh) * 2021-02-24 2022-09-09 中国海洋大学 一种新型氨肽酶及其可溶性表达方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2532858B2 (ja) 1985-04-01 1996-09-11 セルテツク リミテツド 形質転換したミエロ―マ細胞系
GB8601597D0 (en) 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
GB8619293D0 (en) * 1986-08-07 1986-09-17 Munn E A Anthelmintic agents
US4879213A (en) * 1986-12-05 1989-11-07 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
GB8809129D0 (en) 1988-04-18 1988-05-18 Celltech Ltd Recombinant dna methods vectors and host cells
NZ230773A (en) * 1988-09-26 1993-04-28 Biotech Australia Pty Ltd Nematode antigenic peptides and vaccines
GB8906156D0 (en) 1989-03-17 1989-05-04 Munn Edward A Production and use of anthelmintic agents and protective immunogens
NL9001832A (nl) * 1990-08-16 1992-03-16 Rijksuniversiteit Specifieke sequenties van dna van een nematode die toegepast kunnen worden bij de diagnostiek van infektie met de nematode.
US5795768A (en) * 1991-02-12 1998-08-18 Heska Corporation Filariid nematode cysteine protease proteins, nucleic acid molecules and uses thereof
GB9209993D0 (en) * 1992-05-08 1992-06-24 Munn Edward A Vaccines
GB9302302D0 (en) * 1993-02-05 1993-03-24 Pitman Moore Inc Process

Also Published As

Publication number Publication date
RU2140986C1 (ru) 1999-11-10
US6534638B1 (en) 2003-03-18
NO944245D0 (no) 1994-11-07
RO117709B1 (ro) 2002-06-28
PT640133E (pt) 2000-12-29
ZA933216B (en) 1994-06-14
AU677582B2 (en) 1997-05-01
GB9209993D0 (en) 1992-06-24
DE69329195T2 (de) 2001-04-05
FI945221A (fi) 1994-11-07
US20030078398A1 (en) 2003-04-24
DE69329195D1 (de) 2000-09-14
US20080145379A1 (en) 2008-06-19
US6066503A (en) 2000-05-23
CA2134326A1 (en) 1993-11-25
NZ252221A (en) 1996-12-20
JPH07508879A (ja) 1995-10-05
GR3034766T3 (en) 2001-02-28
CN1053699C (zh) 2000-06-21
CZ274494A3 (en) 1995-08-16
DK0640133T3 (da) 2000-12-18
AU4077593A (en) 1993-12-13
SK132394A3 (en) 1995-07-11
HUT71847A (en) 1996-02-28
EP0640133A1 (en) 1995-03-01
ATE195346T1 (de) 2000-08-15
BG99246A (bg) 1995-07-28
CN1084563A (zh) 1994-03-30
ES2151506T3 (es) 2001-01-01
FI945221A0 (fi) 1994-11-07
EP0640133B1 (en) 2000-08-09
PL175900B1 (pl) 1999-03-31
WO1993023542A1 (en) 1993-11-25
RU94046017A (ru) 1997-03-20
NO944245L (no) 1995-01-06
HU218041B (hu) 2000-05-28

Similar Documents

Publication Publication Date Title
BG62700B1 (bg) Молекули на рекомбинантна дезоксирибонуклеинова киселина (днк), кодиращи ензими аминопептидаза,и приложението им за получаването на ваксини против хелминтни инфекции
JP2907813B2 (ja) コクシジウム症予防用抗原性蛋白質およびそれを含有するワクチン
JP2009077713A (ja) アイメリア・マキシマ(Eimeriamaxima)の配偶子母細胞由来の組換え56及び82kDa各抗原をコードする核酸及びその使用
Cheesman et al. The gene encoding topoisomerase II from Plasmodium falciparum
Khalife et al. Cloning of the gene encoding a Schistosoma mansoni antigen homologous to human Ro/SS-A autoantigen
CA2135547A1 (en) Coccidiosis poultry vaccine
NZ222717A (fi)
HUT56852A (en) Process for producing anticoagulant and vermicidal proteins
KR101242757B1 (ko) 개 코로나 바이러스 중화항원 결정기를 포함하는 스파이크재조합 단백질 및 이를 포함하는 백신 조성물
US5618542A (en) Vaccines comprising antigenic polypeptides of Taenia ovis
US7135552B2 (en) Mite galectin
AU696260B2 (en) Helminth parasite antigen with aminopeptidase-like activity
JPH07504088A (ja) 単包条虫感染に対する防御抗原およびそのような抗原を含有するワクチン
GB2219590A (en) Antigenic polypeptides of taena ovis
JPH10298104A (ja) ワクチン
CA2172492A1 (en) Protective antigens against parasites
JP4925236B2 (ja) マダニセメントタンパク質を含むワクチン
AU2003270190A1 (en) Ostertagia vaccine