DK0640133T3 - Rekombinante DNA-molekyler, der koder for aminopeptidaseenzymer og deres anvendelse i fremstillingen af vacciner mod helmin - Google Patents

Rekombinante DNA-molekyler, der koder for aminopeptidaseenzymer og deres anvendelse i fremstillingen af vacciner mod helmin

Info

Publication number
DK0640133T3
DK0640133T3 DK93910164T DK93910164T DK0640133T3 DK 0640133 T3 DK0640133 T3 DK 0640133T3 DK 93910164 T DK93910164 T DK 93910164T DK 93910164 T DK93910164 T DK 93910164T DK 0640133 T3 DK0640133 T3 DK 0640133T3
Authority
DK
Denmark
Prior art keywords
preparation
recombinant dna
dna molecules
molecules encoding
helminth
Prior art date
Application number
DK93910164T
Other languages
English (en)
Inventor
Margaret Bawtree Cresce Graham
Edward Albert Munn
Trevor Stanley Smith
David Patrick Knox
Joanna Jane Oliver
Susan Elizabeth Newton
Original Assignee
Babraham Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Babraham Inst filed Critical Babraham Inst
Application granted granted Critical
Publication of DK0640133T3 publication Critical patent/DK0640133T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0003—Invertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • C07K14/4354—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms from nematodes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
DK93910164T 1992-05-08 1993-05-07 Rekombinante DNA-molekyler, der koder for aminopeptidaseenzymer og deres anvendelse i fremstillingen af vacciner mod helmin DK0640133T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929209993A GB9209993D0 (en) 1992-05-08 1992-05-08 Vaccines
PCT/GB1993/000943 WO1993023542A1 (en) 1992-05-08 1993-05-07 Recombinant dna molecules encoding aminopeptidase enzymes and their use in the preparation of vaccines against helminth infections

Publications (1)

Publication Number Publication Date
DK0640133T3 true DK0640133T3 (da) 2000-12-18

Family

ID=10715227

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93910164T DK0640133T3 (da) 1992-05-08 1993-05-07 Rekombinante DNA-molekyler, der koder for aminopeptidaseenzymer og deres anvendelse i fremstillingen af vacciner mod helmin

Country Status (25)

Country Link
US (4) US6066503A (da)
EP (1) EP0640133B1 (da)
JP (1) JPH07508879A (da)
CN (1) CN1053699C (da)
AT (1) ATE195346T1 (da)
AU (1) AU677582B2 (da)
BG (1) BG62700B1 (da)
CA (1) CA2134326A1 (da)
CZ (1) CZ274494A3 (da)
DE (1) DE69329195T2 (da)
DK (1) DK0640133T3 (da)
ES (1) ES2151506T3 (da)
FI (1) FI945221A0 (da)
GB (1) GB9209993D0 (da)
GR (1) GR3034766T3 (da)
HU (1) HU218041B (da)
NO (1) NO944245L (da)
NZ (1) NZ252221A (da)
PL (1) PL175900B1 (da)
PT (1) PT640133E (da)
RO (1) RO117709B1 (da)
RU (1) RU2140986C1 (da)
SK (1) SK132394A3 (da)
WO (1) WO1993023542A1 (da)
ZA (1) ZA933216B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6099843A (en) * 1991-02-12 2000-08-08 Heska Corporation Parasitic helminth PLA2 proteins
US6156556A (en) * 1991-12-13 2000-12-05 Heska Corporation Flea protease proteins, nucleic acid molecules, and uses thereof
US5972645A (en) * 1991-12-13 1999-10-26 Heska Corporation Flea serine protease nucleic acid molecules
US6210920B1 (en) 1991-12-13 2001-04-03 Heska Corporation Flea protease proteins, nucleic acid molecules, and uses thereof
US6121035A (en) * 1991-12-13 2000-09-19 Heska Corporation Flea aminopeptidase proteins and uses thereof
US6150125A (en) * 1991-12-13 2000-11-21 Heska Corporation Flea protease proteins and uses thereof
US6146870A (en) * 1991-12-13 2000-11-14 Heska Corporation Flea protease proteins
GB9209993D0 (en) * 1992-05-08 1992-06-24 Munn Edward A Vaccines
GB9302302D0 (en) * 1993-02-05 1993-03-24 Pitman Moore Inc Process
GB9303681D0 (en) * 1993-02-24 1993-04-14 Pitman Moore Inc Vaccines
GB9322702D0 (en) 1993-11-03 1993-12-22 Agricultural & Food Res Vaccines
BR9305075A (pt) * 1993-12-16 1995-08-08 Fundacao Oswaldo Cruz Antígeno para conferir imunidade protetora contra infecções helmínticas em humanos e animais,e processo de vacinação para aplicação na imunoprofilaxia de doenças helmintológicas de interesse veterinário e médico
US6214579B1 (en) 1994-10-18 2001-04-10 Heska Corporation Flea leucine aminopeptidase nucleic acid molecules and uses thereof
US6204010B1 (en) 1995-06-07 2001-03-20 Heska Corporation Flea protease proteins, nucleic acid molecules, and uses thereof
US6139840A (en) * 1995-10-18 2000-10-31 Heska Corporation Methods of eliciting an antibody response using flea protease proteins and homologs thereof
IL120704A0 (en) * 1996-04-24 1998-04-05 Heska Corp Flea protease proteins nucleic acid molecules and uses thereof
US20040006204A1 (en) 2002-04-02 2004-01-08 Miriam Tendler Synthetic active peptide fragments
US7951557B2 (en) 2003-04-27 2011-05-31 Protalix Ltd. Human lysosomal proteins from plant cell culture
RU2468076C2 (ru) 2007-05-07 2012-11-27 Проталикс Лтд. Одноразовое устройство для культивирования и сбора растительной ткани и/или клеток, способ и система культивирования и сбора растительной ткани и/или растительных клеток
US20080294361A1 (en) * 2007-05-24 2008-11-27 Popp Shane M Intelligent execution system for the monitoring and execution of vaccine manufacturing
ES2325243B1 (es) 2008-02-27 2011-05-04 Universidad De Granada Antigeno recombinante.
US9052304B2 (en) 2009-03-13 2015-06-09 Terrasep, Llc Methods and apparatus for centrifugal liquid chromatography
CN112961848B (zh) * 2021-02-24 2022-09-09 中国海洋大学 一种新型氨肽酶及其可溶性表达方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2532858B2 (ja) 1985-04-01 1996-09-11 セルテツク リミテツド 形質転換したミエロ―マ細胞系
GB8601597D0 (en) 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
GB8619293D0 (en) * 1986-08-07 1986-09-17 Munn E A Anthelmintic agents
US4879213A (en) * 1986-12-05 1989-11-07 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
GB8809129D0 (en) 1988-04-18 1988-05-18 Celltech Ltd Recombinant dna methods vectors and host cells
NZ230773A (en) * 1988-09-26 1993-04-28 Biotech Australia Pty Ltd Nematode antigenic peptides and vaccines
GB8906156D0 (en) 1989-03-17 1989-05-04 Munn Edward A Production and use of anthelmintic agents and protective immunogens
NL9001832A (nl) * 1990-08-16 1992-03-16 Rijksuniversiteit Specifieke sequenties van dna van een nematode die toegepast kunnen worden bij de diagnostiek van infektie met de nematode.
US5795768A (en) * 1991-02-12 1998-08-18 Heska Corporation Filariid nematode cysteine protease proteins, nucleic acid molecules and uses thereof
GB9209993D0 (en) * 1992-05-08 1992-06-24 Munn Edward A Vaccines
GB9302302D0 (en) * 1993-02-05 1993-03-24 Pitman Moore Inc Process

Also Published As

Publication number Publication date
RU2140986C1 (ru) 1999-11-10
US6534638B1 (en) 2003-03-18
NO944245D0 (no) 1994-11-07
RO117709B1 (ro) 2002-06-28
PT640133E (pt) 2000-12-29
ZA933216B (en) 1994-06-14
AU677582B2 (en) 1997-05-01
GB9209993D0 (en) 1992-06-24
DE69329195T2 (de) 2001-04-05
FI945221A (fi) 1994-11-07
US20030078398A1 (en) 2003-04-24
DE69329195D1 (de) 2000-09-14
US20080145379A1 (en) 2008-06-19
US6066503A (en) 2000-05-23
CA2134326A1 (en) 1993-11-25
NZ252221A (en) 1996-12-20
JPH07508879A (ja) 1995-10-05
GR3034766T3 (en) 2001-02-28
CN1053699C (zh) 2000-06-21
CZ274494A3 (en) 1995-08-16
AU4077593A (en) 1993-12-13
SK132394A3 (en) 1995-07-11
HUT71847A (en) 1996-02-28
EP0640133A1 (en) 1995-03-01
ATE195346T1 (de) 2000-08-15
BG99246A (bg) 1995-07-28
CN1084563A (zh) 1994-03-30
ES2151506T3 (es) 2001-01-01
BG62700B1 (bg) 2000-05-31
FI945221A0 (fi) 1994-11-07
EP0640133B1 (en) 2000-08-09
PL175900B1 (pl) 1999-03-31
WO1993023542A1 (en) 1993-11-25
RU94046017A (ru) 1997-03-20
NO944245L (no) 1995-01-06
HU218041B (hu) 2000-05-28

Similar Documents

Publication Publication Date Title
DK0640133T3 (da) Rekombinante DNA-molekyler, der koder for aminopeptidaseenzymer og deres anvendelse i fremstillingen af vacciner mod helmin
TR27515A (tr) Tospovirüslerin bir rna dizisine veya onunla ilgili rna dizilerine transkripsiyon icin bir dna kodlamasini iceren rekombinant dna olusumlari ve bunlarin kullanimi.
DK289688D0 (da) Ekspression af proapolipoprotein a-i.
DK244289A (da) Fibronectinbindende protein, dets anvendelse og fremstilling samt midler til brug ved fremstillingen
DK0981630T3 (da) Polypeptider med prolyldipeptidylaminopeptidaseaktivitet og nukleinsyrer, der koder for samme
PT726955E (pt) Proteinas quimericas compreendendo polipeptidos borrelia: suas utilizacoes
FI961202A (fi) Grb3-3-geeni, sen variantteja ja niiden käyttöjä
ES2069742T3 (es) Proteina de la capsida del calicivirus felino y secuencia nucleotida.
DK1082423T3 (da) Cyclin E2-gener og -proteiner
ATE166390T1 (de) Anti-katze immundefiziensvirus (fiv) impfstoffe
DK0793721T3 (da) Peptider, der er i stand til at binde sig til GAP-proteinets SH3-domæne, nukleotidsekvenser, der koder derfor, fremstilling og anvendelse deraf
DE69840637D1 (de) Zusammensetzungen zur steigerung der effizienz von impfstoffen unter verwendung von chemokinen
DK487787A (da) Aminosyresekvens af l-phenylalaninammoniaklyase, dna-sekevens der koder for samme, rekombinant dna-plasmid og rekombinant mikroorganisme indeholdende dette samt fremgangsmaade til fremstilling af l-phenylalaninammoniaklyase ved dyrkning af denne organisme
DK0691404T3 (da) Vaccine til immunisering mod TBE-virusinfektioner samt en fremgangsmåde til fremstilling deraf
ES2059801T3 (es) Nuevas linfoquinas, secuencias de adn que codifican para estas linfoquinas, y composiciones farmaceuticas conteniendo estas linfoquinas.