BG34908A3 - Method for preparing d- 6- n- propylergolines - Google Patents

Method for preparing d- 6- n- propylergolines

Info

Publication number
BG34908A3
BG34908A3 BG049173A BG4917380A BG34908A3 BG 34908 A3 BG34908 A3 BG 34908A3 BG 049173 A BG049173 A BG 049173A BG 4917380 A BG4917380 A BG 4917380A BG 34908 A3 BG34908 A3 BG 34908A3
Authority
BG
Bulgaria
Prior art keywords
propylergolines
preparing
formulated
points
formula
Prior art date
Application number
BG049173A
Other languages
Bulgarian (bg)
English (en)
Inventor
Edmund Kornfeld
Nicholas Bach
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of BG34908A3 publication Critical patent/BG34908A3/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG049173A 1979-10-01 1980-09-29 Method for preparing d- 6- n- propylergolines BG34908A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/080,768 US4246265A (en) 1979-10-01 1979-10-01 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds

Publications (1)

Publication Number Publication Date
BG34908A3 true BG34908A3 (en) 1983-12-15

Family

ID=22159504

Family Applications (1)

Application Number Title Priority Date Filing Date
BG049173A BG34908A3 (en) 1979-10-01 1980-09-29 Method for preparing d- 6- n- propylergolines

Country Status (32)

Country Link
US (1) US4246265A (fr)
EP (1) EP0026671B1 (fr)
JP (1) JPS5657787A (fr)
KR (1) KR830003478A (fr)
AT (1) AT373251B (fr)
AU (1) AU529508B2 (fr)
BE (1) BE885385A (fr)
BG (1) BG34908A3 (fr)
CA (1) CA1137079A (fr)
CH (1) CH645642A5 (fr)
CS (1) CS223834B2 (fr)
DD (1) DD153372A5 (fr)
DE (1) DE3069771D1 (fr)
DK (1) DK413780A (fr)
EG (1) EG14583A (fr)
ES (1) ES8200697A1 (fr)
FI (1) FI803025A (fr)
FR (1) FR2466465A1 (fr)
GB (1) GB2058790B (fr)
GR (1) GR70067B (fr)
HU (1) HU181766B (fr)
IE (1) IE50429B1 (fr)
IL (1) IL61143A0 (fr)
IT (1) IT1133631B (fr)
NZ (1) NZ195053A (fr)
PH (1) PH15021A (fr)
PL (1) PL226917A1 (fr)
PT (1) PT71840B (fr)
RO (1) RO81115B (fr)
SU (1) SU976851A3 (fr)
YU (1) YU247280A (fr)
ZA (1) ZA805959B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH644606A5 (de) * 1980-09-23 1984-08-15 Sandoz Ag Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten.
DE3216870A1 (de) * 1982-05-03 1983-11-03 Schering AG, 1000 Berlin und 4709 Bergkamen Pharmazeutische zubereitungen mit zytostatischer wirkung
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4683313A (en) * 1985-06-24 1987-07-28 Eli Lilly And Company 2-alkyl(or phenyl)thio-6-N alkyl ergolines and 4-dialkylaminotetrahydrobenz[c,d]indoles
US4782152A (en) * 1985-08-16 1988-11-01 Eli Lilly And Company Decyanation of pergolide intermediate
US4772709A (en) * 1985-10-01 1988-09-20 Eli Lilly And Company Process of making ketoalkanol esters of dihydrolysergic acid
FR2589734B1 (fr) * 1985-11-13 1988-09-02 Roussel Uclaf Utilisation de derives de l'ergoline a l'obtention d'un medicament a visee geriatrique
US5668155A (en) * 1988-05-10 1997-09-16 The General Hospital Corporation Administration of pirenzepine, methyl scopolamine and other muscarinic receptor antagonists for treatment of lipid metabolism disorders
DE3913756A1 (de) * 1989-04-21 1990-10-25 Schering Ag 8(beta)-substituierte ergoline, verfahren zu ihrer herstellung und ihre verwendung
IT1307934B1 (it) * 1999-01-27 2001-11-29 Poli Ind Chimica Spa Processo per la preparazione di derivati alchimercaptometilergolinici.
US6388079B1 (en) * 2000-08-29 2002-05-14 Scinopharm Singapore Pte Ltd. Process for preparing pergolide
US7019140B2 (en) 2002-03-15 2006-03-28 Antibioticos S.P.A. Process for the synthesis of pergolide
US8821915B2 (en) 2002-08-09 2014-09-02 Veroscience, Llc Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders
GB0409785D0 (en) * 2004-04-30 2004-06-09 Resolution Chemicals Ltd Preparation of cabergoline
GB0505965D0 (en) * 2005-03-23 2005-04-27 Resolution Chemicals Ltd Preparation of cabergoline
US7339060B2 (en) 2005-03-23 2008-03-04 Resolution Chemicals, Ltd. Preparation of cabergoline
US20070197576A1 (en) * 2006-02-08 2007-08-23 Resolution Chemicals Limited Production of Cabergoline and Novel Polymorphic Form Thereof
NZ728804A (en) 2014-09-25 2022-10-28 Boehringer Ingelheim Vetmedica Gmbh Combination treatment of sglt2 inhibitors and dopamine agonists for preventing metabolic disorders in equine animals
WO2019234069A1 (fr) 2018-06-08 2019-12-12 Boehringer Ingelheim Vetmedica Gmbh Compositions pharmaceutiques liquides comprenant du pergolide

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3901894A (en) * 1974-06-06 1975-08-26 Lilly Co Eli 8-thiomethylergolines
DE2657771A1 (de) * 1976-01-02 1977-07-14 Sandoz Ag Neue organische verbindungen, ihre verwendung und herstellung
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4202979A (en) * 1979-01-11 1980-05-13 Eli Lilly And Company 6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds

Also Published As

Publication number Publication date
FR2466465A1 (fr) 1981-04-10
KR830003478A (ko) 1983-06-20
ES495520A0 (es) 1981-11-16
CS223834B2 (en) 1983-11-25
US4246265A (en) 1981-01-20
FI803025A (fi) 1981-04-02
EG14583A (en) 1985-03-31
IL61143A0 (en) 1980-11-30
EP0026671B1 (fr) 1984-12-05
AU6280780A (en) 1981-04-09
NZ195053A (en) 1983-07-29
AT373251B (de) 1984-01-10
DK413780A (da) 1981-04-02
SU976851A3 (ru) 1982-11-23
IE802036L (en) 1981-04-01
PL226917A1 (fr) 1981-06-05
PH15021A (en) 1982-05-13
JPS5657787A (en) 1981-05-20
ATA487480A (de) 1983-05-15
DE3069771D1 (en) 1985-01-17
IT1133631B (it) 1986-07-09
DD153372A5 (de) 1982-01-06
GB2058790A (en) 1981-04-15
YU247280A (en) 1983-02-28
FR2466465B1 (fr) 1983-11-25
RO81115A (fr) 1983-02-15
PT71840A (en) 1980-10-01
PT71840B (en) 1981-06-09
ES8200697A1 (es) 1981-11-16
IT8025004A0 (it) 1980-09-29
GR70067B (fr) 1982-07-26
CA1137079A (fr) 1982-12-07
BE885385A (fr) 1981-03-25
HU181766B (en) 1983-11-28
EP0026671A1 (fr) 1981-04-08
IE50429B1 (en) 1986-04-16
GB2058790B (en) 1983-06-08
ZA805959B (en) 1982-04-28
RO81115B (ro) 1983-02-28
CH645642A5 (fr) 1984-10-15
AU529508B2 (en) 1983-06-09

Similar Documents

Publication Publication Date Title
BG30015A3 (en) Method for obtaining of triphenylalkene derivatives
BG37074A3 (en) Method for preparing derivatives of proline
BG40654A3 (en) Method for preparing cycloalkyltriazoles
BG38333A3 (en) Method for preparing substituted phenylcarboxyoximes
BG28061A3 (en) Method of obtaining of hexahydrodibenzopyranones
BG31946A4 (en) Method for obtaining of 4- acylamino- phenyl- ethanolamines
BG34908A3 (en) Method for preparing d- 6- n- propylergolines
BG32851A3 (en) Method for obtaining of 3, 4, 5, 6- tetrahydro- 2 h- 1- benzoxycin
BG35330A3 (en) Method for preparing 3- iodine- methylcephalosporines
BG40482A3 (en) Method for preparing phenetanolamines
BG28068A3 (en) Method of obtaining of 3-chlorcephalosporines
BG41124A3 (en) Method for preparing benzamides
BG28849A3 (en) Method of obtaining of gamapyrons
BG32853A3 (en) Method for obtaining of 1- oxadethiacephalosporine
BG35746A3 (en) Method for preparing 1- cyclohexenylmethylpyrolidines
BG33292A3 (en) Method for obtaining of penamsulphooxide derivatives
BG34911A3 (en) Method for preparing cephalosporines
BG28054A3 (en) Method of obtaining of 2-(4-aroylpiperazine-1-il)-4- amino-6,7-dimetoxyhinazoline
BG35896A3 (en) Method for preparing 3- halogen- 3- cephem compounds
BG38337A3 (en) Method for preparing 6 alpha- methylhydrocortisonic derivatives
BG35032A3 (en) Method for preparing 1, 1, 2- triphenylpropene derivatives
BG35895A3 (en) Method for preparing of n- substituted- 2- haloacetanilides
BG36633A3 (en) Method for preparing 3- hydroxycephalosporines
BG28062A3 (en) Method of obtaining of 6a,10a, cishexahydrodibenzopyranones
BG36345A3 (en) Method for preparing cyclopentenic derivatives