BG20805A3 - Метод за получаване на субституирани азапуринони - Google Patents
Метод за получаване на субституирани азапуринониInfo
- Publication number
- BG20805A3 BG20805A3 BG019250A BG1925071A BG20805A3 BG 20805 A3 BG20805 A3 BG 20805A3 BG 019250 A BG019250 A BG 019250A BG 1925071 A BG1925071 A BG 1925071A BG 20805 A3 BG20805 A3 BG 20805A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- azapurinones
- preparing substituted
- substituted
- preparing
- substituted azapurinones
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5955670 | 1970-12-15 | ||
| GB5955270 | 1970-12-15 | ||
| GB4975671A GB1338235A (en) | 1970-12-15 | 1971-10-26 | Azapurinones |
| GB5345771 | 1971-11-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG20805A3 true BG20805A3 (bg) | 1975-12-20 |
Family
ID=27449009
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG019250A BG20805A3 (bg) | 1970-12-15 | 1971-12-15 | Метод за получаване на субституирани азапуринони |
| BG020380A BG20807A3 (bg) | 1970-12-15 | 1971-12-15 | Метод за получаване на соли азапуринони |
| BG020379A BG20806A3 (bg) | 1970-12-15 | 1971-12-15 | Метод за получаване на субституирани азапуринони |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG020380A BG20807A3 (bg) | 1970-12-15 | 1971-12-15 | Метод за получаване на соли азапуринони |
| BG020379A BG20806A3 (bg) | 1970-12-15 | 1971-12-15 | Метод за получаване на субституирани азапуринони |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US3987160A (enExample) |
| JP (1) | JPS5310599B1 (enExample) |
| AR (4) | AR192602A1 (enExample) |
| AT (4) | AT315839B (enExample) |
| AU (1) | AU458277B2 (enExample) |
| BE (1) | BE776683A (enExample) |
| BG (3) | BG20805A3 (enExample) |
| CH (5) | CH552610A (enExample) |
| DD (1) | DD95007A5 (enExample) |
| DE (1) | DE2162096A1 (enExample) |
| DK (1) | DK141249B (enExample) |
| FI (1) | FI53457C (enExample) |
| FR (1) | FR2118078B1 (enExample) |
| GB (1) | GB1338235A (enExample) |
| HK (1) | HK42177A (enExample) |
| HU (1) | HU165079B (enExample) |
| IE (1) | IE35897B1 (enExample) |
| IL (1) | IL38364A (enExample) |
| IS (1) | IS1099B6 (enExample) |
| LU (1) | LU64457A1 (enExample) |
| NL (1) | NL174943C (enExample) |
| NO (1) | NO134257C (enExample) |
| OA (1) | OA03930A (enExample) |
| SE (1) | SE393381B (enExample) |
| ZM (1) | ZM18971A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1493685A (en) * | 1970-12-15 | 1977-11-30 | May & Baker Ltd | 8-azapurinones |
| BE792648A (fr) * | 1971-12-13 | 1973-06-12 | May & Baker Ltd | Derives de l'isoquinoleine |
| FR2406638A1 (fr) * | 1977-10-21 | 1979-05-18 | May & Baker Ltd | Nouvelles aza-8 purinones-6, leur preparation et les compositions pharmaceutiques les contenant |
| EP0007727B1 (en) * | 1978-07-24 | 1983-11-30 | Beecham Group Plc | Benzopyranotriazoles, preparation of these compounds and pharmaceutical composition containing them |
| JPS60226887A (ja) * | 1984-04-25 | 1985-11-12 | Dai Ichi Seiyaku Co Ltd | トリアゾロピリミジン誘導体 |
| CA1303037C (en) * | 1987-02-02 | 1992-06-09 | Smith Kline & French Laboratories Limited | Purinone derivatives as bronchodilators vasodilators and anti-allergic agents |
| ES2051886T3 (es) * | 1987-04-07 | 1994-07-01 | Ciba Geigy Ag | Procedimiento para la obtencion de nuevos derivados de la 3h-1,2,3-triazolo(4,5-d)pirimidina. |
| US5204353A (en) * | 1987-04-07 | 1993-04-20 | Ciba-Geigy Corporation | 3-benzyl-3H-1,2,3-triazolo[4,5-d]pyrimidines, compositions thereof, and method of treating epilepsy therewith |
| FR2618073B1 (fr) * | 1987-07-16 | 1990-09-07 | Pf Medicament | Comprimes de type a matrice hydrophile a base de salbutamol et leur procede de preparation |
| GB8817651D0 (en) * | 1988-07-25 | 1988-09-01 | Smith Kline French Lab | Chemical compounds |
| DE4211239C2 (de) * | 1992-04-03 | 1995-11-16 | Max Planck Gesellschaft | Arzneimittel gegen Herz-Kreislauf-Erkrankungen |
| US5734053A (en) * | 1992-06-26 | 1998-03-31 | Pfizer Inc | Purinone antianginal agents |
| GB9213623D0 (en) * | 1992-06-26 | 1992-08-12 | Pfizer Ltd | Therapeutic agents |
| GB9311920D0 (en) | 1993-06-09 | 1993-07-28 | Pfizer Ltd | Therapeutic agents |
| US6818229B1 (en) | 1993-09-20 | 2004-11-16 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia |
| US6129930A (en) * | 1993-09-20 | 2000-10-10 | Bova; David J. | Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night |
| US6080428A (en) * | 1993-09-20 | 2000-06-27 | Bova; David J. | Nicotinic acid compositions for treating hyperlipidemia and related methods therefor |
| US6676967B1 (en) * | 1993-09-20 | 2004-01-13 | Kos Pharmaceuticals, Inc. | Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia |
| US20080045573A1 (en) * | 1993-09-20 | 2008-02-21 | Bova David J | Methods and Sustained Release Nicotinic Acid Compositions for Treating Hyperlipidemia |
| US6746691B2 (en) | 1993-09-20 | 2004-06-08 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics |
| GB9404485D0 (en) * | 1994-03-09 | 1994-04-20 | Cancer Res Campaign Tech | Benzamide analogues |
| NZ504436A (en) | 1997-11-12 | 2001-08-31 | Bayer Ag | 2-Phenyl substituted imidazotriazinones as phosphodiesterase inhibitors |
| DE19838705A1 (de) * | 1998-08-26 | 2000-03-02 | Bayer Ag | Neue Dihydro-(1,2,3)-triazolo-[4,5-d]pyrimidin-7-one |
| IT1318674B1 (it) * | 2000-08-08 | 2003-08-27 | Nicox Sa | Faramaci per l'incontinenza. |
| DE10232113A1 (de) | 2002-07-16 | 2004-01-29 | Bayer Ag | Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| DE102005009240A1 (de) | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften |
| MX354786B (es) | 2007-06-04 | 2018-03-21 | Synergy Pharmaceuticals Inc | Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos. |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| EP2321341B1 (en) | 2008-07-16 | 2017-02-22 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| EA201391254A1 (ru) | 2011-03-01 | 2014-02-28 | Синерджи Фармасьютикалз Инк. | Способ получения агонистов гуанилатциклазы c |
| JP6499591B2 (ja) | 2013-02-25 | 2019-04-10 | シナジー ファーマシューティカルズ インコーポレイテッド | 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト |
| JP2016514671A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼのアゴニストおよびその使用 |
| WO2014151200A2 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| CN105764916B (zh) | 2013-06-05 | 2021-05-18 | 博士医疗爱尔兰有限公司 | 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法 |
| EP3492106B1 (en) | 2013-08-09 | 2021-02-17 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| BR112019012251A2 (pt) | 2016-12-14 | 2019-11-05 | Respira Therapeutics, Inc | métodos e composições para tratamento de hipertensão pulmonar e outros distúrbios pulmonares |
| TWI845600B (zh) | 2019-01-24 | 2024-06-21 | 美商普羅米修斯生物科學股份有限公司 | Gpr35調節劑 |
| EP3972599B1 (en) | 2019-05-21 | 2025-10-22 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
| CA3186635A1 (en) * | 2020-07-23 | 2022-01-27 | Robert Higuchi | Therapeutic agents targeting gpr35 |
| JP2025513455A (ja) | 2022-04-22 | 2025-04-24 | バーテックス ファーマシューティカルズ インコーポレイテッド | 疼痛の治療のためのヘテロアリール化合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2407204A (en) * | 1944-07-22 | 1946-09-03 | American Cyanamid Co | Triazolo (d) pyrimidines and methods of preparing the same |
| US2993039A (en) * | 1959-11-06 | 1961-07-18 | Upjohn Co | Preparing nu-glycosides of aldose and ketose sugars |
-
1971
- 1971-10-26 GB GB4975671A patent/GB1338235A/en not_active Expired
- 1971-12-06 DK DK596371AA patent/DK141249B/da not_active IP Right Cessation
- 1971-12-14 LU LU64457D patent/LU64457A1/xx unknown
- 1971-12-14 IE IE1583/71A patent/IE35897B1/xx unknown
- 1971-12-14 NL NLAANVRAGE7117142,A patent/NL174943C/xx not_active IP Right Cessation
- 1971-12-14 CH CH222574A patent/CH552610A/fr not_active IP Right Cessation
- 1971-12-14 IS IS2047A patent/IS1099B6/is unknown
- 1971-12-14 SE SE7116090A patent/SE393381B/xx unknown
- 1971-12-14 OA OA54440A patent/OA03930A/xx unknown
- 1971-12-14 CH CH1853772A patent/CH556860A/xx not_active IP Right Cessation
- 1971-12-14 DD DD159572A patent/DD95007A5/xx unknown
- 1971-12-14 AU AU36867/71A patent/AU458277B2/en not_active Expired
- 1971-12-14 IL IL38364A patent/IL38364A/xx unknown
- 1971-12-14 HU HUMA2296A patent/HU165079B/hu unknown
- 1971-12-14 BE BE776683A patent/BE776683A/xx not_active IP Right Cessation
- 1971-12-14 FI FI3560/71A patent/FI53457C/fi active
- 1971-12-14 NO NO4614/71A patent/NO134257C/no unknown
- 1971-12-14 CH CH1853672A patent/CH550814A/fr not_active IP Right Cessation
- 1971-12-14 ZM ZM189/71A patent/ZM18971A1/xx unknown
- 1971-12-14 JP JP10078571A patent/JPS5310599B1/ja active Pending
- 1971-12-14 CH CH1853872A patent/CH546779A/fr not_active IP Right Cessation
- 1971-12-14 FR FR7144869A patent/FR2118078B1/fr not_active Expired
- 1971-12-14 CH CH1823271A patent/CH555351A/fr not_active IP Right Cessation
- 1971-12-14 DE DE19712162096 patent/DE2162096A1/de active Granted
- 1971-12-15 BG BG019250A patent/BG20805A3/xx unknown
- 1971-12-15 AR AR239632A patent/AR192602A1/es active
- 1971-12-15 AT AT272473A patent/AT315839B/de not_active IP Right Cessation
- 1971-12-15 BG BG020380A patent/BG20807A3/xx unknown
- 1971-12-15 AT AT272373A patent/AT317211B/de not_active IP Right Cessation
- 1971-12-15 BG BG020379A patent/BG20806A3/xx unknown
- 1971-12-15 AT AT1075671A patent/AT315838B/de not_active IP Right Cessation
- 1971-12-15 AT AT272273A patent/AT319235B/de not_active IP Right Cessation
-
1972
- 1972-12-06 AR AR245509A patent/AR199468A1/es active
- 1972-12-06 AR AR245510A patent/AR192689A1/es active
- 1972-12-06 AR AR245508A patent/AR199467A1/es active
-
1973
- 1973-05-29 US US05/364,425 patent/US3987160A/en not_active Expired - Lifetime
-
1977
- 1977-08-11 HK HK421/77A patent/HK42177A/xx unknown
Also Published As
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