BE776683A - Azapurinones - Google Patents

Azapurinones

Info

Publication number
BE776683A
BE776683A BE776683A BE776683A BE776683A BE 776683 A BE776683 A BE 776683A BE 776683 A BE776683 A BE 776683A BE 776683 A BE776683 A BE 776683A BE 776683 A BE776683 A BE 776683A
Authority
BE
Belgium
Prior art keywords
azapurinones
Prior art date
Application number
BE776683A
Other languages
English (en)
Original Assignee
May & Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB5955270 priority Critical
Priority to GB5955670 priority
Priority to GB4975671A priority patent/GB1338235A/en
Priority to GB5345771 priority
Application filed by May & Baker Ltd filed Critical May & Baker Ltd
Publication of BE776683A publication Critical patent/BE776683A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulfur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulfur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
BE776683A 1970-12-15 1971-12-14 Azapurinones BE776683A (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
GB5955270 1970-12-15
GB5955670 1970-12-15
GB4975671A GB1338235A (en) 1970-12-15 1971-10-26 Azapurinones
GB5345771 1971-11-17

Publications (1)

Publication Number Publication Date
BE776683A true BE776683A (fr) 1972-06-14

Family

ID=27449009

Family Applications (1)

Application Number Title Priority Date Filing Date
BE776683A BE776683A (fr) 1970-12-15 1971-12-14 Azapurinones

Country Status (25)

Country Link
US (1) US3987160A (fr)
JP (1) JPS5310599B1 (fr)
AR (4) AR192602A1 (fr)
AT (4) AT317211B (fr)
AU (1) AU458277B2 (fr)
BE (1) BE776683A (fr)
BG (3) BG20807A3 (fr)
CH (5) CH550814A (fr)
DD (1) DD95007A5 (fr)
DE (1) DE2162096C2 (fr)
DK (1) DK141249C (fr)
FI (1) FI53457C (fr)
FR (1) FR2118078B1 (fr)
GB (1) GB1338235A (fr)
HK (1) HK42177A (fr)
HU (1) HU165079B (fr)
IE (1) IE35897B1 (fr)
IL (1) IL38364A (fr)
IS (1) IS1099B6 (fr)
LU (1) LU64457A1 (fr)
NL (1) NL174943C (fr)
NO (1) NO134257C (fr)
OA (1) OA03930A (fr)
SE (1) SE393381B (fr)
ZM (1) ZM18971A1 (fr)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1493685A (en) * 1970-12-15 1977-11-30 May & Baker Ltd 8-azapurinones
BE792648A (fr) * 1971-12-13 1973-06-12 May & Baker Ltd Derives de l'isoquinoleine
FR2406638B1 (fr) * 1977-10-21 1982-02-05 May & Baker Ltd
EP0007727B1 (fr) * 1978-07-24 1983-11-30 Beecham Group Plc Benzopyranotriazoles, préparation de ces composés et composition pharmaceutique les contenant
JPH0421676B2 (fr) * 1984-04-25 1992-04-13 Daiichi Seiyaku Co
CA1303037C (fr) * 1987-02-02 1992-06-09 Smith Kline & French Laboratories Limited Derives de purinone utilises comme bronchodilatateurs,vasodilatateurs et agents anti-allergiques
DE3873812D1 (de) * 1987-04-07 1992-09-24 Ciba Geigy Ag 3h-1,2,3-triazolo(4,5-d)pyrimidine.
US5204353A (en) * 1987-04-07 1993-04-20 Ciba-Geigy Corporation 3-benzyl-3H-1,2,3-triazolo[4,5-d]pyrimidines, compositions thereof, and method of treating epilepsy therewith
FR2618073B1 (fr) * 1987-07-16 1990-09-07 Pf Medicament Comprimes de type a matrice hydrophile a base de salbutamol et leur procede de preparation
GB8817651D0 (en) * 1988-07-25 1988-09-01 Smith Kline French Lab Chemical compounds
DE4211239C2 (de) * 1992-04-03 1995-11-16 Max Planck Gesellschaft Arzneimittel gegen Herz-Kreislauf-Erkrankungen
GB9213623D0 (en) * 1992-06-26 1992-08-12 Pfizer Ltd Therapeutic agents
US5734053A (en) * 1992-06-26 1998-03-31 Pfizer Inc Purinone antianginal agents
GB9311920D0 (en) 1993-06-09 1993-07-28 Pfizer Ltd Therapeutic agents
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics
US6080428A (en) * 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US20080045573A1 (en) * 1993-09-20 2008-02-21 Bova David J Methods and Sustained Release Nicotinic Acid Compositions for Treating Hyperlipidemia
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US6676967B1 (en) * 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US6129930A (en) * 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
GB9404485D0 (en) * 1994-03-09 1994-04-20 Cancer Res Campaign Tech Benzamide analogues
DE19881732C1 (de) 1997-11-12 2002-01-31 Bayer Ag 2-Phenyl-substituierte Imidazotriazinone
DE19838705A1 (de) * 1998-08-26 2000-03-02 Bayer Ag Neue Dihydro-(1,2,3)-triazolo-[4,5-d]pyrimidin-7-one
IT1318674B1 (it) * 2000-08-08 2003-08-27 Nicox Sa Faramaci per l'incontinenza.
DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
DE102005009240A1 (de) 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2527360B1 (fr) 2007-06-04 2015-10-28 Synergy Pharmaceuticals Inc. Agonistes de guanylase cyclase utiles pour le traitement de troubles gastro-intestinaux, d'inflammation, de cancer et d'autres troubles
JP2011522828A (ja) 2008-06-04 2011-08-04 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
CA2730603C (fr) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonistes de la guanylate cyclase utiles dans le traitement des affections gastro-intestinales, de l'inflammation gastro-intestinale, du cancer gastro-intestinal et d'autres affections
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EA201391254A1 (ru) 2011-03-01 2014-02-28 Синерджи Фармасьютикалз Инк. Способ получения агонистов гуанилатциклазы c
AU2014218599C1 (en) 2013-02-25 2018-09-06 Bausch Health Ireland Limited Guanylate cyclase receptor agonists for use in colonic cleansing
CA2905438A1 (fr) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonistes de la guanylate cyclase et leurs utilisations
CA2905435A1 (fr) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions utiles pour le traitement de troubles gastro-intestinaux
EA201592263A1 (ru) 2013-06-05 2016-05-31 Синерджи Фармасьютикалз, Инк. ULTRASCULAR AGONISTS OF GUANYLACYCLASE C, METHOD OF THEIR RECEIVING AND USING
WO2015021358A2 (fr) 2013-08-09 2015-02-12 Dominique Charmot Composés et procédés d'inhibition du transport de phosphate
CN110381951A (zh) 2016-12-14 2019-10-25 瑞必治公司 用于治疗肺性高血压和其他肺病症的方法及组合物
US20200368223A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Methods for inhibiting phosphate transport

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2407204A (en) * 1944-07-22 1946-09-03 American Cyanamid Co Triazolo (d) pyrimidines and methods of preparing the same
US2993039A (en) * 1959-11-06 1961-07-18 Upjohn Co Preparing nu-glycosides of aldose and ketose sugars

Also Published As

Publication number Publication date
GB1338235A (en) 1973-11-21
JPS5310599B1 (fr) 1978-04-14
DK141249B (da) 1980-02-11
BG20807A3 (fr) 1975-12-20
FI53457C (fi) 1978-05-10
CH556860A (de) 1974-12-13
DE2162096A1 (fr) 1972-07-06
OA3930A (fr) 1975-08-14
CH552610A (fr) 1974-08-15
AT315838B (de) 1974-06-10
AT317211B (de) 1974-08-26
DD95007A5 (fr) 1973-01-12
IS1099B6 (is) 1982-11-18
AR192602A1 (es) 1973-02-28
AR192689A1 (es) 1973-02-28
CH546779A (fr) 1974-03-15
DK141249C (fr) 1980-08-04
IL38364A (en) 1975-08-31
IE35897B1 (en) 1976-06-23
IS2047A7 (is) 1972-06-16
CH550814A (fr) 1974-06-28
AR199467A1 (es) 1974-09-09
US3987160A (en) 1976-10-19
OA03930A (fr) 1975-08-14
AR199468A1 (es) 1974-09-09
FR2118078B1 (fr) 1975-08-01
HK42177A (en) 1977-08-19
AU3686771A (en) 1973-06-21
DE2162096C2 (fr) 1988-02-11
NL7117142A (fr) 1972-06-19
NL174943C (en) 1984-09-03
NL174943B (en) 1984-04-02
AT315839B (de) 1974-06-10
CH555351A (fr) 1974-10-31
IL38364D0 (en) 1972-02-29
BE776683A1 (fr)
NO134257C (fr) 1976-09-08
ZM18971A1 (en) 1972-08-21
HU165079B (fr) 1974-06-28
SE393381B (sv) 1977-05-09
IE35897L (en) 1972-06-15
BG20806A3 (fr) 1975-12-20
FI53457B (fr) 1978-01-31
AT319235B (de) 1974-12-10
BG20805A3 (fr) 1975-12-20
LU64457A1 (fr) 1972-08-23
FR2118078A1 (fr) 1972-07-28
AU458277B2 (en) 1975-02-20
NO134257B (fr) 1976-05-31

Similar Documents

Publication Publication Date Title
CH545100A (fr) Attelle
BE770904A (fr) Distributeur
BE773201A (fr) Purgeur
BE781055A (fr) Triazoles
DE2131490A1 (de) Luftmischduese
DE2135791B2 (de) Fluessigkeitsreibungskupplung
DE2111338B2 (de) Plakatstaender
DE2019345B2 (de) Tauchanker-elektromagnet
DE2154987B2 (de) Uebertragungsmaterial
DE2618694A1 (de) Azapurinone
FI55349B (fi) Mindre skummande tvaettmedelkomposition
DE2004372B2 (de) Sitzmoebel
DE2209325B2 (de) Waermeaustauschrohr
FI56287B (fi) Jonisationsbrandalarmanordning
FI56018C (fi) Foerfarande foer framstaellning av 5-azapyrimidinnukleosider
CH536609A (fr) Cigarette
BE776683A (fr) Azapurinones
DE2151655A1 (de) Mikrowellenwaermeapparat
CH538385A (fr) Véhicule
BE770345A (fr) Krachtapparaat
FI56081B (fi) Fjaederkoppling med deformerbara flaensar
FI56431B (fi) Gaengad foerbindning foer slagborrstaenger
FI56356B (fi) Behaollare saerskilt foer groensaker saosom bladselleri
CH533769A (de) Accumulateur hydro-pneumatique
BE761447A (fr) Termineur

Legal Events

Date Code Title Description
RE Lapsed

Owner name: MAY & BAKER LTD

Effective date: 19881231