BG108363A - Крипто блокиращи антитела и тяхното използване - Google Patents
Крипто блокиращи антитела и тяхното използване Download PDFInfo
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28678201P | 2001-04-26 | 2001-04-26 | |
| US29302001P | 2001-05-17 | 2001-05-17 | |
| US30109101P | 2001-06-26 | 2001-06-26 | |
| US36700202P | 2002-03-22 | 2002-03-22 | |
| PCT/US2002/011950 WO2002088170A2 (en) | 2001-04-26 | 2002-04-17 | Cripto blocking antibodies and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG108363A true BG108363A (bg) | 2004-09-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG108363A BG108363A (bg) | 2001-04-26 | 2003-11-14 | Крипто блокиращи антитела и тяхното използване |
Country Status (34)
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|---|---|
| US (6) | US7531174B2 (zh) |
| EP (3) | EP2316486A3 (zh) |
| JP (4) | JP4307845B2 (zh) |
| KR (1) | KR100592357B1 (zh) |
| CN (1) | CN100352501C (zh) |
| AR (3) | AR037223A1 (zh) |
| AT (2) | ATE420659T1 (zh) |
| BG (1) | BG108363A (zh) |
| BR (1) | BR0209254A (zh) |
| CA (2) | CA2443840C (zh) |
| CL (1) | CL2009002199A1 (zh) |
| CY (1) | CY1108960T1 (zh) |
| CZ (1) | CZ20033208A3 (zh) |
| DE (1) | DE60230868D1 (zh) |
| DK (1) | DK1390389T3 (zh) |
| EA (1) | EA007469B1 (zh) |
| EE (1) | EE200300528A (zh) |
| ES (1) | ES2321065T3 (zh) |
| GE (1) | GEP20074091B (zh) |
| HK (1) | HK1058935A1 (zh) |
| HU (1) | HUP0501113A3 (zh) |
| IS (1) | IS2662B (zh) |
| MX (1) | MXPA03009797A (zh) |
| MY (2) | MY150237A (zh) |
| NO (1) | NO20034805L (zh) |
| NZ (1) | NZ566268A (zh) |
| PL (1) | PL207087B1 (zh) |
| PT (1) | PT1390389E (zh) |
| RS (2) | RS51635B (zh) |
| SG (1) | SG157951A1 (zh) |
| SI (1) | SI1390389T1 (zh) |
| SK (1) | SK14432003A3 (zh) |
| TR (1) | TR200301846T2 (zh) |
| WO (1) | WO2002088170A2 (zh) |
Families Citing this family (97)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPR395801A0 (en) | 2001-03-26 | 2001-04-26 | Austin Research Institute, The | Antibodies against cancer |
| US20090123470A1 (en) * | 2001-03-26 | 2009-05-14 | The Macfarlane Burnet Istitute For Medical Research And Public Health Ltd. | Antibodies Against Cancer |
| ATE420659T1 (de) | 2001-04-26 | 2009-01-15 | Biogen Idec Inc | Criptoblockierende antikörper und deren verwendung |
| US7582299B2 (en) | 2001-04-26 | 2009-09-01 | Biogen Idec Ma Inc. | Cripto-specific antibodies |
| JP2005520566A (ja) * | 2002-03-22 | 2005-07-14 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | Ｃｒｉｐｔｏ特異的抗体 |
| AU2004252171B2 (en) | 2003-06-27 | 2011-04-21 | Biogen Ma Inc. | Modified binding molecules comprising connecting peptides |
| ATE437950T1 (de) * | 2003-09-15 | 2009-08-15 | Res Dev Foundation | Cripto-antagonismus von activin und tgf-b signalisierung |
| KR101192496B1 (ko) | 2003-11-06 | 2012-10-18 | 시애틀 지네틱스, 인크. | 리간드에 접합될 수 있는 모노메틸발린 화합물 |
| WO2005047327A2 (en) | 2003-11-12 | 2005-05-26 | Biogen Idec Ma Inc. | NEONATAL Fc RECEPTOR (FcRn)-BINDING POLYPEPTIDE VARIANTS, DIMERIC Fc BINDING PROTEINS AND METHODS RELATED THERETO |
| CN114053429A (zh) | 2004-06-01 | 2022-02-18 | 健泰科生物技术公司 | 抗体-药物偶联物和方法 |
| RU2412947C2 (ru) | 2004-09-23 | 2011-02-27 | Дженентек, Инк. | Антитела, сконструированные на основе цистеинов, и их конъюгаты |
| US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
| WO2006074399A2 (en) | 2005-01-05 | 2006-07-13 | Biogen Idec Ma Inc. | Multispecific binding molecules comprising connecting peptides |
| DK1838736T3 (da) * | 2005-01-05 | 2013-06-03 | Biogen Idec Inc | Cripto-bindende molekyler |
| US20100105610A1 (en) * | 2006-07-28 | 2010-04-29 | Children's Memorial Hospital | Methods of Inhibiting Tumor Cell Aggressiveness Using the Microenvironment of Human Embryonic Stem Cells |
| US20100330081A1 (en) * | 2007-06-01 | 2010-12-30 | Biogen Idec Ma Inc. | Cripto binding molecules |
| US20110123443A1 (en) * | 2008-04-21 | 2011-05-26 | Merck & Co., Inc. | Pancreatic beta-cell mass biomarker |
| WO2010054328A2 (en) * | 2008-11-07 | 2010-05-14 | Research Development Foundation | Compositions and methods for the inhibition of cripto/grp78 complex formation and signaling |
| JP2013504585A (ja) | 2009-09-09 | 2013-02-07 | セントローズ， エルエルシー | 細胞外標的化薬物複合体 |
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| CN103561771B (zh) | 2011-03-17 | 2019-01-04 | 伯明翰大学 | 重新定向的免疫治疗 |
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| JP6392763B2 (ja) | 2012-10-12 | 2018-09-19 | エイディーシー・セラピューティクス・エス・アーＡｄｃ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｓａ | ピロロベンゾジアゼピン−抗体結合体 |
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