BG108272A - Арилсулфонамиди като противовирусни средства - Google Patents

Арилсулфонамиди като противовирусни средства Download PDF

Info

Publication number
BG108272A
BG108272A BG108272A BG10827203A BG108272A BG 108272 A BG108272 A BG 108272A BG 108272 A BG108272 A BG 108272A BG 10827203 A BG10827203 A BG 10827203A BG 108272 A BG108272 A BG 108272A
Authority
BG
Bulgaria
Prior art keywords
hydroxy
amino
alkyl
halogen
general formula
Prior art date
Application number
BG108272A
Other languages
Bulgarian (bg)
English (en)
Inventor
Tobias Wunberg
Wolfgang Bender
Peter Eckenberg
Sabine Hallenberger
Kerstin Henninger
Joerg Keldenich
Armin Kern
Siegfried Raddatz
Juergen Reefschlaeger
Gunter Schmidt
Holger Zimmermann
Franz Zumpe
Martin Radtke
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10148598A external-priority patent/DE10148598A1/de
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of BG108272A publication Critical patent/BG108272A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
BG108272A 2001-04-19 2003-10-14 Арилсулфонамиди като противовирусни средства BG108272A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10119137 2001-04-19
DE10148598A DE10148598A1 (de) 2001-04-19 2001-10-02 Neue Arylsulfonamide als antivirale Mittel

Publications (1)

Publication Number Publication Date
BG108272A true BG108272A (bg) 2004-10-29

Family

ID=26009118

Family Applications (1)

Application Number Title Priority Date Filing Date
BG108272A BG108272A (bg) 2001-04-19 2003-10-14 Арилсулфонамиди като противовирусни средства

Country Status (20)

Country Link
US (1) US7115612B2 (enExample)
EP (1) EP1383749B1 (enExample)
JP (1) JP4480941B2 (enExample)
CN (1) CN1516695A (enExample)
AT (1) ATE308529T1 (enExample)
BG (1) BG108272A (enExample)
BR (1) BR0209054A (enExample)
CA (1) CA2444123C (enExample)
DE (1) DE50204780D1 (enExample)
EE (1) EE200300515A (enExample)
ES (1) ES2252455T3 (enExample)
HU (1) HUP0303813A3 (enExample)
IL (1) IL158324A0 (enExample)
MX (1) MXPA03009548A (enExample)
NO (1) NO20034667L (enExample)
PL (1) PL363990A1 (enExample)
RU (1) RU2003133750A (enExample)
SK (1) SK12662003A3 (enExample)
UY (1) UY27263A1 (enExample)
WO (1) WO2002085869A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20050168A2 (en) * 2002-08-23 2005-10-31 Rigel Pharmaceuticals Pyridyl substituted heterocycles useful for treating or preventing hcv infection
DE10319612A1 (de) 2003-05-02 2004-11-18 Bayer Healthcare Ag Substituierte Dihydrochinazoline
EP4101846B1 (en) 2003-04-11 2023-08-02 PTC Therapeutics, Inc. 1,2,4-oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease
DE102006009928A1 (de) * 2006-03-03 2007-09-06 Aicuris Gmbh & Co. Kg Substituierte Arylsulfonamide
EP2387995A1 (en) 2006-03-30 2011-11-23 PTC Therapeutics, Inc. Methods for the production of functional protein from DNA having a nonsense mutation and the treatment of disorders associated therewith
US20080255203A1 (en) * 2007-04-12 2008-10-16 Abbott Laboratories Heterocyclic compounds and their methods of use
CA2692379A1 (en) * 2007-07-02 2009-01-08 Boehringer Ingelheim International Gmbh Antiproliferative compounds based on 5-membered heterocycles
EP2177521A1 (en) * 2008-10-14 2010-04-21 Almirall, S.A. New 2-Amidothiadiazole Derivatives
EP2202232A1 (en) * 2008-12-26 2010-06-30 Laboratorios Almirall, S.A. 1,2,4-oxadiazole derivatives and their therapeutic use
CN103119036B (zh) * 2010-06-28 2018-05-08 拜耳知识产权有限责任公司 作为杀虫剂的杂环化合物
JP2013531687A (ja) 2010-07-16 2013-08-08 パーデュー、ファーマ、リミテッド、パートナーシップ ナトリウムチャネル遮断剤としてのピリジン化合物
WO2013136170A1 (en) 2012-03-16 2013-09-19 Purdue Pharma L.P. Substituted pyridines as sodium channel blockers
US9284310B2 (en) 2012-11-03 2016-03-15 Boehringer Ingelheim International Gmbh Inhibitors of cytomegalovirus
EP2914592B1 (en) 2012-11-03 2017-10-11 Boehringer Ingelheim International GmbH Inhibitors of cytomegalovirus
EP2935257B1 (en) 2012-12-20 2018-02-07 Purdue Pharma LP Cyclic sulfonamides as sodium channel blockers
WO2015134711A1 (en) 2014-03-06 2015-09-11 Ptc Therapeutics, Inc. Pharmaceutical compositions and salts of a 1,2,4-oxadiazole benzoic acid
US10730866B2 (en) 2014-04-07 2020-08-04 Purdue Pharma L.P. Indole derivatives and use thereof
EP3256461B1 (en) * 2015-02-13 2023-09-13 Azienda Ospedaliera Universitaria Senese Urea and sulfonamide derivatives as human helicase ddx3 inhibitors useful in the treatment of viral diseases
TW201729807A (zh) 2015-10-30 2017-09-01 Ptc治療公司 用於治療癲癇的方法
EP3601274A1 (en) * 2017-03-31 2020-02-05 Perenna Pharmaceuticals, Inc. Compounds useful as inhibitors of alcat 1

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19802437A1 (de) 1998-01-23 1999-07-29 Bayer Ag Verwendung von substituierten Sulfonamiden als anitvirale Mittel und neue Stoffe
PL351374A1 (en) * 1999-04-19 2003-04-07 Shionogi & Co Sulfonamide derivatives having oxadiazole rings

Also Published As

Publication number Publication date
UY27263A1 (es) 2002-11-29
EP1383749B1 (de) 2005-11-02
DE50204780D1 (de) 2005-12-08
HUP0303813A3 (en) 2005-05-30
WO2002085869A1 (de) 2002-10-31
JP2004531536A (ja) 2004-10-14
JP4480941B2 (ja) 2010-06-16
RU2003133750A (ru) 2005-05-10
NO20034667D0 (no) 2003-10-17
ES2252455T3 (es) 2006-05-16
EP1383749A1 (de) 2004-01-28
CA2444123A1 (en) 2002-10-31
NO20034667L (no) 2003-12-12
US7115612B2 (en) 2006-10-03
CN1516695A (zh) 2004-07-28
HUP0303813A2 (hu) 2004-03-29
BR0209054A (pt) 2004-04-20
MXPA03009548A (es) 2004-05-24
SK12662003A3 (sk) 2004-04-06
US20040176374A1 (en) 2004-09-09
ATE308529T1 (de) 2005-11-15
CA2444123C (en) 2010-09-21
PL363990A1 (en) 2004-11-29
EE200300515A (et) 2004-02-16
IL158324A0 (en) 2004-05-12

Similar Documents

Publication Publication Date Title
JP4480941B2 (ja) 抗ウイルス剤としての新規アリールスルホンアミド
AU2010307006B2 (en) Hematopoietic growth factor mimetic small molecule compounds and their uses
CN1264384A (zh) 稠合1,2,4-噻二嗪衍生物及其制备方法和用途
KR20040070348A (ko) Hcv 감염 치료용으로 유용한 치환된 디페닐헤테로사이클
CZ20012297A3 (cs) Piperidiny jako modulátory CCR5
KR20030088509A (ko) 항바이러스제로서의 신규한 아릴술폰아미드
CA2608718A1 (en) 1, 2, 4-triazole derivatives as vasopressin antagonists
MXPA05005406A (es) Compuestos quimicos novedosos.
KR20050100615A (ko) 화합물, 조성물 및 방법
JP2010532772A (ja) イミダゾ−、ピラゾロピラジン類およびイミダゾトリアジン類およびそれらの使用
AU2007344509A1 (en) 5-([1,3,4] oxadiazol-2-yl)-1H-indazol and 5-([1,3,4] thiadiazol-2-yl)-1H-indazol derivatives as SGK inhibitors for the treatment of diabetes
AU2007216543A1 (en) Hetero-bycyclic antiviral compounds
CN121548418A (zh) 二环杂芳基化合物
AU2007214602A1 (en) Heterocyclic antiviral compounds
EA016300B1 (ru) НОВЫЕ ГЕТЕРОЦИКЛИЧЕСКИЕ ИНГИБИТОРЫ NF-κB
KR20090014223A (ko) 니코틴성 아세틸콜린 수용체 리간드로서의 2-페닐-5-아미노-1,3,4-옥사디아졸 및 그의 용도
EP4532476A1 (en) Flavivirus inhibitors
JPWO2004111024A1 (ja) チアジアゾリン誘導体
JP4481003B2 (ja) ヘテロシクリルアリールスルホンアミド類
CZ279559B6 (cs) Deriváty amidů kyseliny thiazolidinkarboxylové mající antialergickou aktivitu,jejich příprava a použití
EP4563146A1 (en) Flavivirus inhibitors
TW202604512A (zh) Tiparp抑制劑化合物