BG106022A - Нови полиморфни форми на противодиабетично средство: метод за тяхното получаване и фармацевтични състави, които ги съдържат - Google Patents
Нови полиморфни форми на противодиабетично средство: метод за тяхното получаване и фармацевтични състави, които ги съдържат Download PDFInfo
- Publication number
- BG106022A BG106022A BG106022A BG10602201A BG106022A BG 106022 A BG106022 A BG 106022A BG 106022 A BG106022 A BG 106022A BG 10602201 A BG10602201 A BG 10602201A BG 106022 A BG106022 A BG 106022A
- Authority
- BG
- Bulgaria
- Prior art keywords
- ethoxy
- phenyl
- phenoxazin
- ethoxypropanoic acid
- arginine salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/38—[b, e]-condensed with two six-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IB1999/000681 WO2000063191A1 (fr) | 1999-04-16 | 1999-04-16 | Nouvelles formes polymorphes d'un agent antidiabetique: procede de preparation et composition pharmaceutique contenant ces dernieres |
IN436MA1999 | 1999-04-19 | ||
PCT/IB2000/000470 WO2000063192A1 (fr) | 1999-04-16 | 2000-04-17 | Nouvelles formes polymorphes d'un agent antidiabetique, leur procede de preparation et compositions pharmaceutiques les renfermant |
Publications (1)
Publication Number | Publication Date |
---|---|
BG106022A true BG106022A (bg) | 2002-04-30 |
Family
ID=26318745
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG106022A BG106022A (bg) | 1999-04-16 | 2001-10-16 | Нови полиморфни форми на противодиабетично средство: метод за тяхното получаване и фармацевтични състави, които ги съдържат |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP1171430A1 (fr) |
CN (1) | CN1351597A (fr) |
AU (1) | AU3831300A (fr) |
BG (1) | BG106022A (fr) |
BR (1) | BR0010683A (fr) |
CA (1) | CA2370401A1 (fr) |
CZ (1) | CZ20013711A3 (fr) |
EE (1) | EE200100529A (fr) |
HR (1) | HRP20010748A2 (fr) |
HU (1) | HUP0200758A3 (fr) |
IL (1) | IL145958A0 (fr) |
MX (1) | MXPA01010472A (fr) |
NO (1) | NO20015016L (fr) |
PL (1) | PL351492A1 (fr) |
RU (1) | RU2001130883A (fr) |
TR (1) | TR200103851T2 (fr) |
WO (1) | WO2000063192A1 (fr) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1634605A3 (fr) | 2000-03-08 | 2006-10-11 | Novo Nordisk A/S | traitement de la dyslipidémie chez un patient souffrant de diabète de type 2 |
US6897199B2 (en) * | 2001-02-05 | 2005-05-24 | Dr. Reddy's Laboratories Ltd. | Pharmaceutically acceptable salts of phenoxazine and phenothiazine compounds |
EP1444219A1 (fr) | 2001-10-12 | 2004-08-11 | Novo Nordisk A/S | Piperidines substituees et leur utilisation dans le traitement de maladies liees au recepteur histaminique h3 |
AU2002351748B2 (en) | 2001-12-21 | 2009-07-09 | Novo Nordisk A/S | Amide derivatives as GK activators |
CN1290843C (zh) * | 2002-04-19 | 2006-12-20 | 费斯制药股份有限公司 | 4-[2-[4-[1-(2-乙氧基乙基)-1H-苯并咪唑-2-基]-1-哌啶基]乙基]-α,α-二甲基苯乙酸的多晶型物 |
WO2004002481A1 (fr) | 2002-06-27 | 2004-01-08 | Novo Nordisk A/S | Activateurs de la glycokinase |
JP2007503453A (ja) | 2003-05-14 | 2007-02-22 | ノボ ノルディスク アクティーゼルスカブ | 肥満症を治療するための新規化合物 |
EP1670815A2 (fr) | 2003-09-30 | 2006-06-21 | Novo Nordisk A/S | Nouveaux agonistes du recepteur de la melanocortine |
JP4865565B2 (ja) | 2003-12-09 | 2012-02-01 | ノヴォ ノルディスク アー/エス | Glp−1アゴニストを用いた食物選択の制御 |
BRPI0506662B8 (pt) | 2004-01-06 | 2021-05-25 | Novo Nordisk As | compostos ativadores de glucoquinase |
US20080113944A1 (en) | 2004-05-04 | 2008-05-15 | Novo Nordisk A/S | Novel Indole Derivatives |
JP2008501765A (ja) | 2004-06-11 | 2008-01-24 | ノボ ノルディスク アクティーゼルスカブ | Glp−1アゴニストを用いた薬剤誘発性肥満の中和 |
WO2006053906A1 (fr) | 2004-11-22 | 2006-05-26 | Novo Nordisk A/S | Formulations solubles stables contenant de l'insuline et un sel de protamine |
WO2006058923A1 (fr) | 2004-12-03 | 2006-06-08 | Novo Nordisk A/S | Composés hétéroaromatiques activants de glucokinase |
CN103110635A (zh) | 2005-07-04 | 2013-05-22 | 海波因特制药有限责任公司 | 组胺h3受体拮抗剂 |
US7884210B2 (en) | 2005-07-14 | 2011-02-08 | Novo Nordisk A/S | Ureido-thiazole glucokinase activators |
EP1910317B1 (fr) | 2005-07-20 | 2013-07-03 | Eli Lilly And Company | Composés joints en position 1-amino |
US7863329B2 (en) | 2005-11-17 | 2011-01-04 | Eli Lilly And Company | Glucagon receptor antagonists, preparation and therapeutic uses |
AU2007229492B2 (en) | 2006-03-28 | 2011-11-03 | High Point Pharmaceuticals, Llc | Benzothiazoles having histamine H3 receptor activity |
EA016026B1 (ru) | 2006-05-29 | 2012-01-30 | ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | 3-(1,3-бензодиоксол-5-ил)-6-(4-циклопропилпиперазин-1-ил)пиридазин, его соли и сольваты и его применение в качестве антагониста н3 рецептора гистамина |
WO2008059025A1 (fr) | 2006-11-15 | 2008-05-22 | High Point Pharmaceuticals, Llc | Nouvelles 2-(2-hydroxyphényl) benzothiadiazines utilisées pour traiter l'obésité et le diabète |
WO2008059026A1 (fr) | 2006-11-15 | 2008-05-22 | High Point Pharmaceuticals, Llc | Nouveaux 2-(2-hydroxyphényl)benzimidazoles utilisés pour traiter l'obésité et le diabète |
JP5226008B2 (ja) | 2007-01-11 | 2013-07-03 | ノボ・ノルデイスク・エー/エス | ウレアグルコキナーゼアクチベーター |
JP2010013472A (ja) * | 2009-09-09 | 2010-01-21 | Faes Farma Sa | 4−[2−[1−(2−エトキシエチル)−1H−ベンズイミダゾール−2−イル]−1−ピペリジニル]エチル]−α,α−ジメチルベンゼノ酢酸の多形体 |
BR112012021231A2 (pt) | 2010-02-26 | 2015-09-08 | Basf Plant Science Co Gmbh | método para acentuar o rendimento em plantas, planta, construto, uso de um construto, método para a produção de uma planta transgênica, partes coletáveis de uma planta, produtos derivados de uma planta, uso de um ácido nucleíco e método para a produção de um produto |
EP2539364A1 (fr) | 2010-02-26 | 2013-01-02 | Novo Nordisk A/S | Peptides de traitement de l'obésité |
CA2792663A1 (fr) | 2010-03-26 | 2011-09-29 | Novo Nordisk A/S | Nouveaux analogues du glucagon |
WO2012104834A1 (fr) | 2011-02-03 | 2012-08-09 | Pharmedica Ltd. | Nouveaux films à dissolution orale pour administration d'insuline, pour traitement du diabète |
US20140031278A1 (en) | 2011-03-28 | 2014-01-30 | Novo Nordisk A/S | Novel Glucagon Analogues |
IN2014CN02448A (fr) | 2011-09-23 | 2015-06-19 | Novo Nordisk As | |
WO2013082106A1 (fr) | 2011-12-02 | 2013-06-06 | The General Hospital Corporation | Différenciation en adipocytes bruns |
JP6594856B2 (ja) | 2013-04-18 | 2019-10-23 | ノヴォ ノルディスク アー/エス | 医療用の安定な遷延性glp−1/グルカゴン受容体コアゴニスト |
EP3151852A1 (fr) | 2014-06-04 | 2017-04-12 | Novo Nordisk A/S | Co-agonistes de récepteur du glucagon/glp-1 à usage médical |
MA49883A (fr) | 2017-03-15 | 2021-04-21 | Novo Nordisk As | Composés bicycliques aptes à se lier au récepteur de mélanocortine 4 |
US20210221867A1 (en) | 2018-05-15 | 2021-07-22 | Novo Nordisk A/S | Compounds Capable of Binding to Melanocortin 4 Receptor |
WO2020053414A1 (fr) | 2018-09-14 | 2020-03-19 | Novo Nordisk A/S | Composés bicycliques aptes à se lier aux agonistes du récepteur de la mélanocortine 4 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
US5248699A (en) * | 1992-08-13 | 1993-09-28 | Pfizer Inc. | Sertraline polymorph |
IN182496B (fr) * | 1996-02-20 | 1999-04-17 | Reddy Research Foundation | |
GB9604242D0 (en) * | 1996-02-28 | 1996-05-01 | Glaxo Wellcome Inc | Chemical compounds |
FR2746099B1 (fr) * | 1996-03-13 | 1998-04-30 | Procede ameliore pour la preparation de derives de l'acide 3-(10-phenothiazyl)-propanoique ou 3-(10-phenoxazyl)-propanoique | |
JP2000511875A (ja) * | 1996-06-19 | 2000-09-12 | ドクター・レディーズ・リサーチ・ファウンデーション | 抗糖尿病活性を増強されたトログリタゾンの新規な多形型及びそれらの製造方法 |
WO1999019313A1 (fr) * | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Nouveaux composes tricycliques et leur utilisation en medecine, procede de preparation de ces derniers et compositions pharmaceutiques les contenant |
AU1887999A (en) * | 1998-01-29 | 1999-08-16 | Dr. Reddy's Research Foundation | Novel alkanoic acids and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
NZ504106A (en) * | 1998-05-27 | 2003-02-28 | Dr | Fused Oxazine, Thiazine and pipyridine compounds, process for their preparation and pharmaceutical compositions containing them |
-
2000
- 2000-04-17 IL IL14595800A patent/IL145958A0/xx unknown
- 2000-04-17 WO PCT/IB2000/000470 patent/WO2000063192A1/fr active Search and Examination
- 2000-04-17 CA CA002370401A patent/CA2370401A1/fr not_active Abandoned
- 2000-04-17 CN CN00807705A patent/CN1351597A/zh active Pending
- 2000-04-17 EE EEP200100529A patent/EE200100529A/xx unknown
- 2000-04-17 MX MXPA01010472A patent/MXPA01010472A/es unknown
- 2000-04-17 AU AU38313/00A patent/AU3831300A/en not_active Abandoned
- 2000-04-17 PL PL00351492A patent/PL351492A1/xx not_active Application Discontinuation
- 2000-04-17 HU HU0200758A patent/HUP0200758A3/hu unknown
- 2000-04-17 BR BR0010683-6A patent/BR0010683A/pt not_active IP Right Cessation
- 2000-04-17 RU RU2001130883/04A patent/RU2001130883A/ru unknown
- 2000-04-17 EP EP00917222A patent/EP1171430A1/fr not_active Withdrawn
- 2000-04-17 CZ CZ20013711A patent/CZ20013711A3/cs unknown
- 2000-04-17 TR TR2001/03851T patent/TR200103851T2/xx unknown
-
2001
- 2001-10-15 NO NO20015016A patent/NO20015016L/no not_active Application Discontinuation
- 2001-10-15 HR HR20010748A patent/HRP20010748A2/hr not_active Application Discontinuation
- 2001-10-16 BG BG106022A patent/BG106022A/bg unknown
Also Published As
Publication number | Publication date |
---|---|
AU3831300A (en) | 2000-11-02 |
MXPA01010472A (es) | 2002-05-06 |
EP1171430A1 (fr) | 2002-01-16 |
EE200100529A (et) | 2002-12-16 |
TR200103851T2 (tr) | 2002-04-22 |
IL145958A0 (en) | 2002-07-25 |
RU2001130883A (ru) | 2004-03-20 |
HUP0200758A2 (hu) | 2002-07-29 |
NO20015016D0 (no) | 2001-10-15 |
CN1351597A (zh) | 2002-05-29 |
PL351492A1 (en) | 2003-04-22 |
HUP0200758A3 (en) | 2003-07-28 |
HRP20010748A2 (en) | 2003-02-28 |
NO20015016L (no) | 2001-12-11 |
WO2000063192A1 (fr) | 2000-10-26 |
BR0010683A (pt) | 2003-07-01 |
CZ20013711A3 (cs) | 2002-07-17 |
CA2370401A1 (fr) | 2000-10-26 |
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