BG104602A - Производни на арилтиазолидиндион - Google Patents
Производни на арилтиазолидиндион Download PDFInfo
- Publication number
- BG104602A BG104602A BG104602A BG10460200A BG104602A BG 104602 A BG104602 A BG 104602A BG 104602 A BG104602 A BG 104602A BG 10460200 A BG10460200 A BG 10460200A BG 104602 A BG104602 A BG 104602A
- Authority
- BG
- Bulgaria
- Prior art keywords
- propyl
- phenyl
- alkyl
- optionally substituted
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/44—Two oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6827197P | 1997-12-19 | 1997-12-19 | |
| GBGB9816279.5A GB9816279D0 (en) | 1998-07-27 | 1998-07-27 | Arylthiazolidinedione derivatives |
| US10523898P | 1998-10-22 | 1998-10-22 | |
| PCT/US1998/027139 WO1999032465A1 (fr) | 1997-12-19 | 1998-12-18 | Derives d'arylthiazolidinedione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG104602A true BG104602A (bg) | 2001-01-31 |
Family
ID=27269416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG104602A BG104602A (bg) | 1997-12-19 | 2000-07-13 | Производни на арилтиазолидиндион |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1040102B1 (fr) |
| JP (1) | JP3373198B2 (fr) |
| KR (1) | KR20010033355A (fr) |
| CN (1) | CN1282325A (fr) |
| AT (1) | ATE352545T1 (fr) |
| AU (1) | AU740733B2 (fr) |
| BG (1) | BG104602A (fr) |
| BR (1) | BR9813801A (fr) |
| CA (1) | CA2315397C (fr) |
| DE (1) | DE69836980T2 (fr) |
| EA (1) | EA200000687A1 (fr) |
| ES (1) | ES2281146T3 (fr) |
| HU (1) | HUP0101366A2 (fr) |
| ID (1) | ID24878A (fr) |
| IL (1) | IL136138A0 (fr) |
| IS (1) | IS5506A (fr) |
| NO (1) | NO20003112L (fr) |
| PL (1) | PL340958A1 (fr) |
| SK (1) | SK9212000A3 (fr) |
| TR (1) | TR200001753T2 (fr) |
| WO (1) | WO1999032465A1 (fr) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9824614D0 (en) | 1998-11-11 | 1999-01-06 | Glaxo Group Ltd | Chemical compounds |
| DE60035639T2 (de) * | 1999-05-20 | 2008-05-21 | Ciba Specialty Chemicals Holding Inc. | Hydroxydiphenyletherverbindungen |
| EP1194146B1 (fr) * | 1999-06-18 | 2006-07-19 | Merck & Co., Inc. | Derives d'arylthiazolidinedione et d'aryloxazolidinedione |
| AU5876900A (en) * | 1999-06-18 | 2001-01-09 | Merck & Co., Inc. | Process for making arylthiazolidinedione derivatives |
| CA2382966A1 (fr) | 1999-08-27 | 2001-03-08 | Eli Lilly And Company | Derives de biaryl-oxa(thia)zole et leur utilisation en tant que modulateurs de ppar |
| WO2001034200A1 (fr) * | 1999-11-10 | 2001-05-17 | Takeda Chemical Industries, Ltd | Inhibiteurs de prise de poids |
| AU2001298065A1 (en) * | 2001-01-12 | 2003-09-02 | Abbott Laboratories | Process for the preparation of matrix metalloproteinase inhibitors |
| US20040077689A1 (en) * | 2001-04-25 | 2004-04-22 | Yasuo Sugiyama | Abc expression promoters |
| WO2004011448A1 (fr) * | 2002-07-25 | 2004-02-05 | Merck & Co., Inc. | Composes therapeutiques destines au traitement d'etats dyslipidemiques |
| CA2507465C (fr) * | 2002-11-26 | 2009-04-28 | Pfizer Products Inc. | Composes de piperidine phenyle a substitution phenyle s'utilisant comme activateurs de ppar |
| CN1319956C (zh) * | 2003-09-12 | 2007-06-06 | 深圳市海粤门生物科技开发有限公司 | 一种噻唑烷二酮的衍生物及其药用制剂的制备方法和应用 |
| AU2004285849B2 (en) * | 2003-09-19 | 2011-04-28 | Janssen Pharmaceutica, N.V. | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
| ES2555031T3 (es) | 2003-09-19 | 2015-12-28 | Janssen Pharmaceutica N.V. | Ácidos y análogos 4-((fenoxialquilo)tio)-fenoxiacéticos |
| ATE363475T1 (de) * | 2004-01-20 | 2007-06-15 | Merck & Co Inc | Antidiabetische oxazolidindione und thiazolidindione |
| WO2006138328A1 (fr) * | 2005-06-14 | 2006-12-28 | Merck & Co., Inc. | Procede de production d'oxazolidinediones anti-diabetiques |
| EP1907381A4 (fr) * | 2005-07-06 | 2009-08-26 | Merck & Co Inc | Oxazolidinediones et thiazolidinediones antidiabétiques |
| EP1909789A4 (fr) * | 2005-07-20 | 2009-10-21 | Merck & Co Inc | Oxazolidinediones et thiazolidinediones antidiabetiques |
| US7858666B2 (en) | 2007-06-08 | 2010-12-28 | Mannkind Corporation | IRE-1α inhibitors |
| CN105001174A (zh) * | 2015-07-14 | 2015-10-28 | 佛山市赛维斯医药科技有限公司 | 含苯并异恶唑和末端腈基苄基类结构的化合物及其用途 |
| CN104987314A (zh) * | 2015-07-14 | 2015-10-21 | 佛山市赛维斯医药科技有限公司 | 含苯并异恶唑和末端硝基苄基类结构的化合物及其用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3053490B2 (ja) * | 1991-02-25 | 2000-06-19 | 杏林製薬株式会社 | チアゾリジン−２，４−ジオン誘導体とその塩及び製造法 |
| JP3906935B2 (ja) * | 1995-12-18 | 2007-04-18 | 杏林製薬株式会社 | Ｎ−置換ジオキソチアゾリジルベンズアミド誘導体及びその製造法 |
| ATE236137T1 (de) * | 1996-02-02 | 2003-04-15 | Merck & Co Inc | Heterocyclische verbindungen als antidiabetische mittel und für die behandlung von fettleibigkeit |
| WO1997028115A1 (fr) * | 1996-02-02 | 1997-08-07 | Merck & Co., Inc. | Agents anti-diabete |
| EP0904079B1 (fr) * | 1996-02-02 | 2004-03-24 | Merck & Co., Inc. | Agents antidiabetiques |
| US5801173A (en) * | 1996-05-06 | 1998-09-01 | Dr. Reddy's Research Foundation | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
-
1998
- 1998-12-18 EP EP98963283A patent/EP1040102B1/fr not_active Expired - Lifetime
- 1998-12-18 DE DE69836980T patent/DE69836980T2/de not_active Expired - Fee Related
- 1998-12-18 ES ES98963283T patent/ES2281146T3/es not_active Expired - Lifetime
- 1998-12-18 CN CN98812229A patent/CN1282325A/zh active Pending
- 1998-12-18 ID IDW20001163A patent/ID24878A/id unknown
- 1998-12-18 IL IL13613898A patent/IL136138A0/xx unknown
- 1998-12-18 BR BR9813801-4A patent/BR9813801A/pt not_active Application Discontinuation
- 1998-12-18 PL PL98340958A patent/PL340958A1/xx not_active Application Discontinuation
- 1998-12-18 KR KR1020007006820A patent/KR20010033355A/ko not_active Application Discontinuation
- 1998-12-18 AU AU18334/99A patent/AU740733B2/en not_active Ceased
- 1998-12-18 JP JP2000525402A patent/JP3373198B2/ja not_active Expired - Fee Related
- 1998-12-18 WO PCT/US1998/027139 patent/WO1999032465A1/fr active IP Right Grant
- 1998-12-18 CA CA002315397A patent/CA2315397C/fr not_active Expired - Fee Related
- 1998-12-18 TR TR2000/01753T patent/TR200001753T2/xx unknown
- 1998-12-18 SK SK921-2000A patent/SK9212000A3/sk unknown
- 1998-12-18 AT AT98963283T patent/ATE352545T1/de not_active IP Right Cessation
- 1998-12-18 EA EA200000687A patent/EA200000687A1/ru unknown
- 1998-12-18 HU HU0101366A patent/HUP0101366A2/hu unknown
-
2000
- 2000-05-23 IS IS5506A patent/IS5506A/is unknown
- 2000-06-16 NO NO20003112A patent/NO20003112L/no not_active Application Discontinuation
- 2000-07-13 BG BG104602A patent/BG104602A/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20003112L (no) | 2000-08-18 |
| BR9813801A (pt) | 2000-10-03 |
| KR20010033355A (ko) | 2001-04-25 |
| PL340958A1 (en) | 2001-03-12 |
| AU740733B2 (en) | 2001-11-15 |
| AU1833499A (en) | 1999-07-12 |
| EP1040102B1 (fr) | 2007-01-24 |
| WO1999032465A1 (fr) | 1999-07-01 |
| EP1040102A4 (fr) | 2002-11-27 |
| EA200000687A1 (ru) | 2000-12-25 |
| CA2315397C (fr) | 2007-08-07 |
| DE69836980D1 (de) | 2007-03-15 |
| HUP0101366A2 (hu) | 2001-09-28 |
| JP3373198B2 (ja) | 2003-02-04 |
| CN1282325A (zh) | 2001-01-31 |
| TR200001753T2 (tr) | 2000-11-21 |
| IL136138A0 (en) | 2001-05-20 |
| JP2001526278A (ja) | 2001-12-18 |
| IS5506A (is) | 2000-05-23 |
| ES2281146T3 (es) | 2007-09-16 |
| ID24878A (id) | 2000-08-31 |
| NO20003112D0 (no) | 2000-06-16 |
| SK9212000A3 (en) | 2001-02-12 |
| EP1040102A1 (fr) | 2000-10-04 |
| ATE352545T1 (de) | 2007-02-15 |
| DE69836980T2 (de) | 2007-11-15 |
| CA2315397A1 (fr) | 1999-07-01 |
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