BG104073A - Метод за получаване на аминопроизводни на алкилоксифуранон, съединения, получени по този метод, и тяхното използване - Google Patents
Метод за получаване на аминопроизводни на алкилоксифуранон, съединения, получени по този метод, и тяхното използванеInfo
- Publication number
- BG104073A BG104073A BG104073A BG10407300A BG104073A BG 104073 A BG104073 A BG 104073A BG 104073 A BG104073 A BG 104073A BG 10407300 A BG10407300 A BG 10407300A BG 104073 A BG104073 A BG 104073A
- Authority
- BG
- Bulgaria
- Prior art keywords
- compounds
- preparing
- alkyloxy
- furanone derivatives
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/60—Two oxygen atoms, e.g. succinic anhydride
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9708932A FR2766188B1 (fr) | 1997-07-15 | 1997-07-15 | Nouveau procede de preparation de derives amines d'alkyloxy furanone, composes issus de ce procede et utilisation de ces composes |
| PCT/FR1998/001480 WO1999003852A1 (fr) | 1997-07-15 | 1998-07-09 | Procede de preparation de derives amines d'alkyloxyfuranone, composes issus de ce procede et utilisation de ces composes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG104073A true BG104073A (bg) | 2001-05-31 |
| BG64050B1 BG64050B1 (bg) | 2003-11-28 |
Family
ID=9509210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG104073A BG64050B1 (bg) | 1997-07-15 | 2000-01-12 | Метод за получаване на аминопроизводни на алкилоксифуранон, съединения, получени по този метод, и тяхното използване |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US6235899B1 (bg) |
| EP (1) | EP0998470B1 (bg) |
| JP (1) | JP4450987B2 (bg) |
| KR (1) | KR100519691B1 (bg) |
| CN (1) | CN100363355C (bg) |
| AP (1) | AP1071A (bg) |
| AR (1) | AR015924A1 (bg) |
| AT (1) | ATE239713T1 (bg) |
| AU (1) | AU744272B2 (bg) |
| BG (1) | BG64050B1 (bg) |
| BR (1) | BR9810896A (bg) |
| CA (1) | CA2296742C (bg) |
| CZ (1) | CZ295312B6 (bg) |
| DE (1) | DE69814395T2 (bg) |
| DK (1) | DK0998470T3 (bg) |
| EA (1) | EA002883B1 (bg) |
| EE (1) | EE03873B1 (bg) |
| ES (1) | ES2197489T3 (bg) |
| FR (1) | FR2766188B1 (bg) |
| HR (1) | HRP20000027B1 (bg) |
| HU (1) | HU230148B1 (bg) |
| ID (1) | ID23784A (bg) |
| IL (1) | IL134031A (bg) |
| ME (1) | ME01708B (bg) |
| NO (1) | NO324508B1 (bg) |
| NZ (1) | NZ502338A (bg) |
| PL (1) | PL200820B1 (bg) |
| PT (1) | PT998470E (bg) |
| RS (1) | RS49832B (bg) |
| SK (1) | SK284168B6 (bg) |
| TR (1) | TR200000117T2 (bg) |
| UA (1) | UA66364C2 (bg) |
| WO (1) | WO1999003852A1 (bg) |
| ZA (1) | ZA986203B (bg) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7053056B2 (en) | 1998-07-02 | 2006-05-30 | Idun Pharmaceuticals, Inc. | C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases |
| AU2001253692B2 (en) | 2000-04-24 | 2006-11-02 | Vertex Pharmaceuticals Incorporated | Process and intermediates for making substituted aspartic acid acetals |
| PE20011350A1 (es) | 2000-05-19 | 2002-01-15 | Vertex Pharma | PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE) |
| JP2003327568A (ja) * | 2000-09-20 | 2003-11-19 | Kanegafuchi Chem Ind Co Ltd | 光学活性β−アミノ酸誘導体の製造方法 |
| WO2002055478A1 (fr) * | 2001-01-16 | 2002-07-18 | Kaneka Corporation | Procede de preparation de derives d'aminolactone optiquement actifs et intermediaires de ces derives |
| CA2557645C (en) | 2004-02-27 | 2013-09-24 | Vertex Pharmaceuticals Incorporated | Caspase inhibitors and uses thereof |
| DK2399916T3 (en) * | 2004-03-12 | 2015-03-02 | Vertex Pharma | A process and intermediates for the preparation of asparaginacetal-caspase inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6204261B1 (en) * | 1995-12-20 | 2001-03-20 | Vertex Pharmaceuticals Incorporated | Inhibitors of interleukin-1β Converting enzyme inhibitors |
| US5716929A (en) * | 1994-06-17 | 1998-02-10 | Vertex Pharmaceuticals, Inc. | Inhibitors of interleukin-1β converting enzyme |
-
1997
- 1997-07-15 FR FR9708932A patent/FR2766188B1/fr not_active Expired - Lifetime
-
1998
- 1998-07-09 EA EA200000127A patent/EA002883B1/ru not_active IP Right Cessation
- 1998-07-09 JP JP2000503076A patent/JP4450987B2/ja not_active Expired - Lifetime
- 1998-07-09 WO PCT/FR1998/001480 patent/WO1999003852A1/fr active IP Right Grant
- 1998-07-09 CA CA002296742A patent/CA2296742C/fr not_active Expired - Lifetime
- 1998-07-09 SK SK30-2000A patent/SK284168B6/sk not_active IP Right Cessation
- 1998-07-09 TR TR2000/00117T patent/TR200000117T2/xx unknown
- 1998-07-09 IL IL13403198A patent/IL134031A/en not_active IP Right Cessation
- 1998-07-09 ES ES98937591T patent/ES2197489T3/es not_active Expired - Lifetime
- 1998-07-09 HU HU0003857A patent/HU230148B1/hu unknown
- 1998-07-09 ME MEP-2000-15A patent/ME01708B/me unknown
- 1998-07-09 KR KR10-2000-7000398A patent/KR100519691B1/ko not_active IP Right Cessation
- 1998-07-09 EE EEP200000024A patent/EE03873B1/xx unknown
- 1998-07-09 NZ NZ502338A patent/NZ502338A/en not_active IP Right Cessation
- 1998-07-09 CZ CZ200065A patent/CZ295312B6/cs not_active IP Right Cessation
- 1998-07-09 PT PT98937591T patent/PT998470E/pt unknown
- 1998-07-09 BR BR9810896-4A patent/BR9810896A/pt not_active Application Discontinuation
- 1998-07-09 AT AT98937591T patent/ATE239713T1/de active
- 1998-07-09 DK DK98937591T patent/DK0998470T3/da active
- 1998-07-09 CN CNB98808967XA patent/CN100363355C/zh not_active Expired - Lifetime
- 1998-07-09 EP EP98937591A patent/EP0998470B1/fr not_active Expired - Lifetime
- 1998-07-09 DE DE69814395T patent/DE69814395T2/de not_active Expired - Lifetime
- 1998-07-09 AU AU86333/98A patent/AU744272B2/en not_active Expired
- 1998-07-09 RS YUP-15/00A patent/RS49832B/sr unknown
- 1998-07-09 US US09/463,014 patent/US6235899B1/en not_active Expired - Lifetime
- 1998-07-09 AP APAP/P/2000/001732A patent/AP1071A/en active
- 1998-07-09 ID IDW20000067A patent/ID23784A/id unknown
- 1998-07-09 PL PL338035A patent/PL200820B1/pl unknown
- 1998-07-13 ZA ZA9806203A patent/ZA986203B/xx unknown
- 1998-07-15 AR ARP980103455A patent/AR015924A1/es not_active Application Discontinuation
- 1998-09-07 UA UA2000020800A patent/UA66364C2/uk unknown
-
2000
- 2000-01-12 BG BG104073A patent/BG64050B1/bg unknown
- 2000-01-14 HR HR20000027A patent/HRP20000027B1/xx not_active IP Right Cessation
- 2000-01-14 NO NO20000182A patent/NO324508B1/no not_active IP Right Cessation
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