BG104034A - Method for the preparation of pharmaceutical compounds of antidepressive effect and against the parkinson syndrome effect - Google Patents
Method for the preparation of pharmaceutical compounds of antidepressive effect and against the parkinson syndrome effectInfo
- Publication number
- BG104034A BG104034A BG104034A BG10403499A BG104034A BG 104034 A BG104034 A BG 104034A BG 104034 A BG104034 A BG 104034A BG 10403499 A BG10403499 A BG 10403499A BG 104034 A BG104034 A BG 104034A
- Authority
- BG
- Bulgaria
- Prior art keywords
- effect
- preparation
- pharmaceutical compounds
- antidepressive
- parkinson syndrome
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9711095.1A GB9711095D0 (en) | 1997-05-29 | 1997-05-29 | Novel process |
GBGB9714875.3A GB9714875D0 (en) | 1997-07-15 | 1997-07-15 | Novel process |
PCT/US1998/011057 WO1998053824A1 (fr) | 1997-05-29 | 1998-05-29 | Nouveau procede |
Publications (1)
Publication Number | Publication Date |
---|---|
BG104034A true BG104034A (en) | 2000-11-30 |
Family
ID=26311618
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG104034A BG104034A (en) | 1997-05-29 | 1999-12-17 | Method for the preparation of pharmaceutical compounds of antidepressive effect and against the parkinson syndrome effect |
Country Status (22)
Country | Link |
---|---|
US (3) | US6489347B1 (fr) |
EP (1) | EP0986389B1 (fr) |
JP (1) | JP2002514222A (fr) |
CN (1) | CN1268889A (fr) |
AP (1) | AP9901698A0 (fr) |
AT (1) | ATE279393T1 (fr) |
AU (1) | AU7708998A (fr) |
BG (1) | BG104034A (fr) |
BR (1) | BR9809687A (fr) |
CA (1) | CA2291251A1 (fr) |
DE (1) | DE69827000D1 (fr) |
EA (1) | EA199901098A1 (fr) |
HU (1) | HUP0003958A3 (fr) |
ID (1) | ID24383A (fr) |
IL (1) | IL133140A0 (fr) |
NO (1) | NO995796D0 (fr) |
NZ (1) | NZ501285A (fr) |
OA (1) | OA11223A (fr) |
PL (1) | PL337513A1 (fr) |
SK (1) | SK159899A3 (fr) |
TR (1) | TR199902929T2 (fr) |
WO (1) | WO1998053824A1 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6438585B2 (en) * | 1998-05-29 | 2002-08-20 | Research In Motion Limited | System and method for redirecting message attachments between a host system and a mobile data communication device |
WO2000026187A1 (fr) * | 1998-11-02 | 2000-05-11 | Synthon B.V. | Procede de production de 4-arylpiperidine-3-carbinols et composes correspondants |
US20010053862A1 (en) * | 1998-12-22 | 2001-12-20 | Bruce Ronsen | Process for preparing arylpiperidine carbinol intermediates and derivatives |
GB9828767D0 (en) * | 1998-12-29 | 1999-02-17 | Smithkline Beecham Plc | Novel process |
IT1313702B1 (it) * | 1999-08-02 | 2002-09-09 | Chemi Spa | Processo per la preparazione di derivati 3-sostituiti di 4-fenil-piperidine. |
GB0003232D0 (en) * | 2000-02-11 | 2000-04-05 | Smithkline Beecham Plc | Novel composition |
US6833458B2 (en) * | 2000-06-05 | 2004-12-21 | Development Center For Biotechnology | Practical syntheses of chiral trans-3, 4-disubstituted piperidines and the intermediates |
CA2433605A1 (fr) * | 2001-01-04 | 2002-07-11 | Ferrer Internacional, S.A. | Procede de preparation de (.plusmn.)-trans-4-p-fluorophenyl-3-hydroxymethyl-1-methylpiperidine |
AU2002330771A1 (en) | 2001-10-22 | 2003-06-10 | Synthon B.V. | N-formyl derivatives of paroxetine |
US20080033050A1 (en) | 2006-08-04 | 2008-02-07 | Richards Patricia Allison Tewe | Method of treating thermoregulatory disfunction with paroxetine |
US9138430B2 (en) * | 2007-12-27 | 2015-09-22 | Mylan Specialty L.P. | Formulation and method for the release of paroxetine in the large intestine |
CN112645951A (zh) * | 2020-12-23 | 2021-04-13 | 上海博栋化学科技有限公司 | 由长春布宁合成的磺酸锍盐类光产酸剂及其合成方法 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2798432A (en) * | 1945-02-27 | 1957-07-09 | Leo T Meister | Delay action fuse |
US2498432A (en) | 1946-07-08 | 1950-02-21 | Hoffmann La Roche | 1-branched lower alkyl-4-phenyl-4-acyloxy-piperidines and their acid addition salts |
GB1422263A (en) | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
US4585777A (en) | 1984-02-07 | 1986-04-29 | A/S Ferrosan | (-)-Trans-4-(4-fluorophenyl)-3-(4-methoxyphenoxy)methylpiperidine for potentiating 5-HT |
US4593036A (en) | 1984-02-07 | 1986-06-03 | A/S Ferrosan | (-)-Trans-4-(4-fluorophenyl)-3-[(4-methoxyphenoxy)methyl]-1-methylpiperidine useful as 5-HT potentiator |
EP0190496A3 (fr) | 1984-12-13 | 1987-05-27 | Beecham Group Plc | Dérivés de la pipéridine à activité gastro-intestinale |
EP0223334B1 (fr) * | 1985-08-10 | 1991-07-10 | Beecham Group Plc | Procédé de préparation d'aryl-pipéridine-carbinols |
GB8520154D0 (en) | 1985-08-10 | 1985-09-18 | Beecham Group Plc | Chemical process |
GB8714707D0 (en) | 1987-06-23 | 1987-07-29 | Beecham Group Plc | Chemical process |
DK715988D0 (da) | 1988-12-22 | 1988-12-22 | Ferrosan As | Etherifikation og dealkylering af piperidin-derivater samt intermediater |
IL98757A (en) | 1990-07-18 | 1997-01-10 | Novo Nordisk As | Piperidine derivatives their preparation and pharmaceutical compositions containing them |
US5258517A (en) | 1992-08-06 | 1993-11-02 | Sepracor, Inc. | Method of preparing optically pure precursors of paroxetine |
GB9305175D0 (en) * | 1993-03-13 | 1993-04-28 | Smithkline Beecham Plc | Novel process |
ES2102295B1 (es) | 1994-03-18 | 1998-04-01 | Ferrer Int | Nuevos compuestos derivados de la n-benzoilmetil-piperidina. |
US5856493A (en) | 1995-02-06 | 1999-01-05 | Smithkline Beecham Corporation | Process for making novel form of paroxeting hydrochloride anhydrate |
US5554383A (en) * | 1995-04-06 | 1996-09-10 | Trustees Of Tufts College | Veterinary method for clinically modifying the behavior of dogs exhibiting canine affective aggression |
JPH11505229A (ja) | 1995-05-17 | 1999-05-18 | ノボ ノルディスク アクティーゼルスカブ | 4−アリール−ピペリジン誘導体を製造する方法 |
WO1997009311A1 (fr) | 1995-09-07 | 1997-03-13 | F. Hoffmann-La Roche Ag | Nouvelles 4-(oxyalcoxyphenyl)-3-oxy-piperidines utiles pour traiter l'insuffisance cardiaque et renale |
ES2121685B1 (es) * | 1996-04-10 | 1999-09-16 | Vita Invest Sa | Procedimiento para la obtencion de (+)-trans-4(4-fluoro-fenil)-3-hidroximetil-1-metilpiperidina. |
JP3446468B2 (ja) | 1996-04-15 | 2003-09-16 | 旭硝子株式会社 | ピペリジンカルビノール類の製造方法 |
DE69739561D1 (de) | 1996-06-13 | 2009-10-15 | Sumitomo Chemical Co | Piperidin Derivative als Zwischenprodukte zur Herstellung von Paroxetine und Verfahren zu ihrer Herstellung |
WO1998045263A1 (fr) | 1997-04-07 | 1998-10-15 | Georgetown University | Analogues de cocaine |
WO2000026187A1 (fr) | 1998-11-02 | 2000-05-11 | Synthon B.V. | Procede de production de 4-arylpiperidine-3-carbinols et composes correspondants |
US6051812A (en) * | 1998-11-16 | 2000-04-18 | Walker; Lawrence | Snow and ice melting blanket device |
-
1998
- 1998-05-29 EA EA199901098A patent/EA199901098A1/ru unknown
- 1998-05-29 TR TR1999/02929T patent/TR199902929T2/xx unknown
- 1998-05-29 HU HU0003958A patent/HUP0003958A3/hu unknown
- 1998-05-29 SK SK1598-99A patent/SK159899A3/sk unknown
- 1998-05-29 PL PL98337513A patent/PL337513A1/xx unknown
- 1998-05-29 WO PCT/US1998/011057 patent/WO1998053824A1/fr not_active Application Discontinuation
- 1998-05-29 CN CN98805522A patent/CN1268889A/zh active Pending
- 1998-05-29 US US09/087,632 patent/US6489347B1/en not_active Expired - Fee Related
- 1998-05-29 BR BR9809687-7A patent/BR9809687A/pt not_active Application Discontinuation
- 1998-05-29 JP JP50100199A patent/JP2002514222A/ja not_active Ceased
- 1998-05-29 AU AU77089/98A patent/AU7708998A/en not_active Abandoned
- 1998-05-29 IL IL13314098A patent/IL133140A0/xx unknown
- 1998-05-29 ID IDW991488A patent/ID24383A/id unknown
- 1998-05-29 AP APAP/P/1999/001698A patent/AP9901698A0/en unknown
- 1998-05-29 NZ NZ501285A patent/NZ501285A/en unknown
- 1998-05-29 CA CA002291251A patent/CA2291251A1/fr not_active Abandoned
- 1998-05-29 DE DE1998627000 patent/DE69827000D1/de not_active Expired - Lifetime
- 1998-05-29 EP EP98925055A patent/EP0986389B1/fr not_active Expired - Lifetime
- 1998-05-29 AT AT98925055T patent/ATE279393T1/de not_active IP Right Cessation
-
1999
- 1999-11-26 NO NO995796A patent/NO995796D0/no not_active Application Discontinuation
- 1999-11-29 OA OA9900263A patent/OA11223A/en unknown
- 1999-12-17 BG BG104034A patent/BG104034A/xx unknown
-
2002
- 2002-05-03 US US10/138,553 patent/US6716985B2/en not_active Expired - Fee Related
-
2004
- 2004-01-14 US US10/757,147 patent/US20040147754A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
NZ501285A (en) | 2001-10-26 |
AU7708998A (en) | 1998-12-30 |
CA2291251A1 (fr) | 1998-12-03 |
BR9809687A (pt) | 2000-07-11 |
TR199902929T2 (xx) | 2000-06-21 |
EP0986389A4 (fr) | 2001-09-12 |
US6716985B2 (en) | 2004-04-06 |
US20020133011A1 (en) | 2002-09-19 |
CN1268889A (zh) | 2000-10-04 |
ATE279393T1 (de) | 2004-10-15 |
WO1998053824A1 (fr) | 1998-12-03 |
EA199901098A1 (ru) | 2000-08-28 |
DE69827000D1 (de) | 2004-11-18 |
EP0986389B1 (fr) | 2004-10-13 |
US6489347B1 (en) | 2002-12-03 |
OA11223A (en) | 2003-06-17 |
JP2002514222A (ja) | 2002-05-14 |
AP9901698A0 (en) | 1999-12-31 |
HUP0003958A2 (hu) | 2001-05-28 |
ID24383A (id) | 2000-07-13 |
PL337513A1 (en) | 2000-08-28 |
EP0986389A1 (fr) | 2000-03-22 |
NO995796L (no) | 1999-11-26 |
SK159899A3 (en) | 2000-06-12 |
IL133140A0 (en) | 2001-03-19 |
HUP0003958A3 (en) | 2001-06-28 |
NO995796D0 (no) | 1999-11-26 |
US20040147754A1 (en) | 2004-07-29 |
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