BG103393A - Method for the preparation of substituted pyridines - Google Patents

Method for the preparation of substituted pyridines

Info

Publication number
BG103393A
BG103393A BG103393A BG10339399A BG103393A BG 103393 A BG103393 A BG 103393A BG 103393 A BG103393 A BG 103393A BG 10339399 A BG10339399 A BG 10339399A BG 103393 A BG103393 A BG 103393A
Authority
BG
Bulgaria
Prior art keywords
preparation
formula
substituted pyridines
compounds
aminogroup
Prior art date
Application number
BG103393A
Other languages
Bulgarian (bg)
English (en)
Inventor
Keith DEVRIES
Robert DOW
Stephn WRIGHT
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of BG103393A publication Critical patent/BG103393A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG103393A 1996-11-14 1999-05-11 Method for the preparation of substituted pyridines BG103393A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3088096P 1996-11-14 1996-11-14
PCT/IB1997/001367 WO1998021184A1 (en) 1996-11-14 1997-11-03 Process for substituted pyridines

Publications (1)

Publication Number Publication Date
BG103393A true BG103393A (en) 2000-07-31

Family

ID=21856496

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103393A BG103393A (en) 1996-11-14 1999-05-11 Method for the preparation of substituted pyridines

Country Status (32)

Country Link
US (1) US6291489B1 (de)
EP (1) EP0938476B1 (de)
JP (1) JP3510635B2 (de)
KR (1) KR20000053314A (de)
CN (1) CN1237160A (de)
AP (1) AP805A (de)
AR (1) AR010584A1 (de)
AT (1) ATE319687T1 (de)
AU (1) AU4634697A (de)
BG (1) BG103393A (de)
BR (1) BR9712951A (de)
CA (1) CA2270386C (de)
CO (1) CO4930261A1 (de)
DE (1) DE69735433D1 (de)
EA (1) EA199900375A1 (de)
GT (1) GT199700118A (de)
HR (1) HRP970612A2 (de)
ID (1) ID18898A (de)
IL (1) IL129688A0 (de)
IS (1) IS5029A (de)
MA (1) MA24401A1 (de)
MY (1) MY132507A (de)
NO (1) NO992296L (de)
OA (1) OA11044A (de)
PA (1) PA8441401A1 (de)
PE (1) PE10299A1 (de)
TN (1) TNSN97172A1 (de)
TR (1) TR199901063T2 (de)
UY (1) UY24774A1 (de)
WO (1) WO1998021184A1 (de)
YU (1) YU22099A (de)
ZA (1) ZA9710186B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9909555A (pt) * 1998-04-08 2000-12-19 Novartis Ag Novartis S A Novar Herbicidas
US6090942A (en) * 1998-10-15 2000-07-18 Pfizer Inc. Process and intermediates for a β3 -adrenergic receptor agonist
CA2362070A1 (en) * 1999-02-16 2000-08-24 Masaru Mitsuda Substituted acetylpyridine derivatives and process for the preparation of intermediates for optically active .beta.3 agonist by the use of the same
US6455734B1 (en) 2000-08-09 2002-09-24 Magnesium Diagnostics, Inc. Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states
DE60015036T2 (de) * 1999-07-23 2006-03-02 Pfizer Products Inc., Groton Zwischenprodukte und ein Verfahren zur Herstellung von beta3-Adrenergischer Rezeptor-Agoniste
US20040265991A1 (en) * 2001-10-17 2004-12-30 Naoaki Taoka Process for preparation of (s)-alpha-halomethylpyridine-methanol derivatives
WO2003072573A1 (en) 2002-02-27 2003-09-04 Pfizer Products Inc. Crystal forms of (r)-2-(2-(4-oxazol-4-yl-phenoxy)-ethylamino)-1-pyridin-3-yl-ethanol
US6864268B2 (en) 2002-02-27 2005-03-08 Pfizer Inc. β3 adrenergic receptor agonists
AU2003248352A1 (en) 2002-02-27 2003-09-09 Pfizer Products Inc. PROCESSES AND INTERMEDIATES USEFUL IN PREPARING Beta3-ADRENERGIC RECEPTOR AGONISTS
EP1424079A1 (de) * 2002-11-27 2004-06-02 Boehringer Ingelheim International GmbH Kombination eines beta-3-Rezeptoragonisten und eines Serotonin und/oder Norepinephrin-Wiederaufnahmeinhibitors
EP1660484B1 (de) 2003-05-09 2008-08-27 F. Hoffmann-La Roche Ag Methylindole und methylpyrrolopyridine als alpha-1-adrenerge agonisten
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
KR20160129109A (ko) 2008-05-23 2016-11-08 아미라 파마슈티칼스 인코포레이티드 5-리폭시게나아제 활성화 단백질 억제제

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4358455A (en) 1980-12-23 1982-11-09 Merck & Co., Inc. Aralkylamindethanol heterocyclic compounds
US5019578A (en) 1987-11-27 1991-05-28 Merck & Co., Inc. β-adrenergic agonists
CA2164009A1 (en) 1993-06-14 1994-12-22 Robert L. Dow Secondary amines as antidiabetic and antiobesity agents
IL113410A (en) * 1994-04-26 1999-11-30 Merck & Co Inc Substituted sulfonamides having an asymmetric center and pharmaceutical compositions containing them
MX9708621A (es) 1995-05-10 1998-02-28 Pfizer AGONISTAS beta-ADRENERGICOS, COMPOSICIONES QUE LOS CONTIENEN Y USO DE LOS MISMOS.
EP0828712A1 (de) 1995-05-10 1998-03-18 Pfizer Inc. Beta-adrenergische agonisten

Also Published As

Publication number Publication date
PE10299A1 (es) 1999-02-10
JP2000504347A (ja) 2000-04-11
EP0938476B1 (de) 2006-03-08
CA2270386A1 (en) 1998-05-22
KR20000053314A (ko) 2000-08-25
NO992296D0 (no) 1999-05-12
JP3510635B2 (ja) 2004-03-29
MA24401A1 (fr) 1998-07-01
ZA9710186B (en) 1999-05-12
TNSN97172A1 (fr) 2005-03-15
US6291489B1 (en) 2001-09-18
EA199900375A1 (ru) 1999-12-29
NO992296L (no) 1999-05-12
GT199700118A (es) 1999-05-05
AU4634697A (en) 1998-06-03
WO1998021184A1 (en) 1998-05-22
IS5029A (is) 1999-04-16
AP805A (en) 2000-01-28
DE69735433D1 (de) 2006-05-04
CO4930261A1 (es) 2000-06-27
ATE319687T1 (de) 2006-03-15
BR9712951A (pt) 1999-12-07
OA11044A (en) 2002-02-20
HRP970612A2 (en) 1998-08-31
AR010584A1 (es) 2000-06-28
UY24774A1 (es) 1998-05-05
MY132507A (en) 2007-10-31
AP9701147A0 (en) 1998-01-31
ID18898A (id) 1998-05-20
PA8441401A1 (es) 2000-05-24
EP0938476A1 (de) 1999-09-01
CA2270386C (en) 2004-08-03
CN1237160A (zh) 1999-12-01
TR199901063T2 (xx) 1999-08-23
IL129688A0 (en) 2000-02-29
YU22099A (sh) 2001-09-28

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