BE901963A - DOSED FORM OF ETOPOSIDE FOR ORAL USE. - Google Patents

DOSED FORM OF ETOPOSIDE FOR ORAL USE.

Info

Publication number
BE901963A
BE901963A BE0/214666A BE214666A BE901963A BE 901963 A BE901963 A BE 901963A BE 0/214666 A BE0/214666 A BE 0/214666A BE 214666 A BE214666 A BE 214666A BE 901963 A BE901963 A BE 901963A
Authority
BE
Belgium
Prior art keywords
oral use
etoposide
acid
dosed form
etopsoside
Prior art date
Application number
BE0/214666A
Other languages
French (fr)
Inventor
S Begum
I Ullah
B C Nunning
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of BE901963A publication Critical patent/BE901963A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

Forme dosée liquide propre à l'administration par voie orale de l'étopsoside, qui est suffisamment concentrée pour etre présentée dans une capsule et qui assure une meilleure absorption du médicament comparé à celle atteinte avec les formulations àusage oral déjà connues. La composition pharmaceutique comprend de l'étoposide, du polyéthylèneglycol, de l'acide taurocholique, de l'éthanol et un acide hydrosoluble, qui est par préférence l'acide citrique.Liquid dosage form suitable for oral administration of etopsoside, which is sufficiently concentrated to be presented in a capsule and which ensures better absorption of the drug compared to that achieved with formulations for oral use already known. The pharmaceutical composition comprises etoposide, polyethylene glycol, taurocholic acid, ethanol and a water-soluble acid, which is preferably citric acid.

BE0/214666A 1984-03-19 1985-03-18 DOSED FORM OF ETOPOSIDE FOR ORAL USE. BE901963A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59114484A 1984-03-19 1984-03-19

Publications (1)

Publication Number Publication Date
BE901963A true BE901963A (en) 1985-09-18

Family

ID=24365235

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/214666A BE901963A (en) 1984-03-19 1985-03-18 DOSED FORM OF ETOPOSIDE FOR ORAL USE.

Country Status (28)

Country Link
JP (1) JPS60209516A (en)
KR (1) KR850006136A (en)
AT (1) AT392904B (en)
AU (1) AU571308B2 (en)
BE (1) BE901963A (en)
CA (1) CA1238578A (en)
CH (1) CH662731A5 (en)
DE (1) DE3509741A1 (en)
DK (1) DK164535C (en)
EG (1) EG17521A (en)
ES (1) ES8702140A1 (en)
FI (1) FI84023C (en)
FR (1) FR2561104B1 (en)
GB (1) GB2155789B (en)
GR (1) GR850688B (en)
IE (1) IE58340B1 (en)
IL (1) IL74615A (en)
IT (1) IT1187640B (en)
LU (1) LU85812A1 (en)
MY (1) MY101916A (en)
NL (1) NL8500739A (en)
NO (1) NO170569C (en)
NZ (1) NZ211078A (en)
OA (1) OA07968A (en)
PT (1) PT80131B (en)
SE (1) SE8501312L (en)
YU (1) YU45243B (en)
ZA (1) ZA851935B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60239418A (en) * 1984-05-15 1985-11-28 Nippon Kayaku Co Ltd Soft capsule containing etoposide
JPS61189230A (en) * 1985-02-19 1986-08-22 Nippon Kayaku Co Ltd Etoposide preparation
DE3629386A1 (en) * 1986-08-29 1988-03-03 Scherer Gmbh R P GELATINE CAPSULES AND METHOD FOR THEIR PRODUCTION
US4927638A (en) * 1986-10-08 1990-05-22 Bristol-Myers Company Etoposide solutions
US5154930A (en) * 1987-03-05 1992-10-13 The Liposome Company, Inc. Pharmacological agent-lipid solution preparation
US5376381A (en) * 1988-02-25 1994-12-27 The Liposome Company, Inc. Integrity protected gelatin
JP2000247911A (en) * 1999-02-26 2000-09-12 Hisamitsu Pharmaceut Co Inc Absorption promoter for large intestine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH580255A5 (en) * 1974-06-04 1976-09-30 Calinter Sa
DE2452785A1 (en) * 1974-11-07 1976-05-13 Universal Oil Prod Co Engine crankcase gases treatment - by catalytic reactor in heat exchange and partial mixture with exhaust gases
FR2358144A1 (en) * 1976-07-13 1978-02-10 Lipha Compsn. for treating biliary lithiasis - contains hymecromone and chenodeoxy-cholic acid, with lower cost and better tolerance
JPS5940137B2 (en) * 1976-10-14 1984-09-28 武田薬品工業株式会社 Pharmaceutical composition for oral administration
FR2410504A1 (en) * 1977-12-05 1979-06-29 Air Liquide Safety control in chemical reactor carrying out oxidations - comprises oxygen concn. monitoring in gaseous phase and nitrogen injections if set concn. is reached
DE2809543A1 (en) * 1978-03-06 1979-09-13 Werner Henke Rendering oil or gas well gases harmless - by desulphurisation and oxidn. in catalytic reactors
JPS60239418A (en) * 1984-05-15 1985-11-28 Nippon Kayaku Co Ltd Soft capsule containing etoposide

Also Published As

Publication number Publication date
GB8506943D0 (en) 1985-04-24
AU3897585A (en) 1985-09-26
CH662731A5 (en) 1987-10-30
FR2561104A1 (en) 1985-09-20
FI84023B (en) 1991-06-28
IL74615A (en) 1988-07-31
EG17521A (en) 1990-06-30
GB2155789A (en) 1985-10-02
LU85812A1 (en) 1985-12-12
JPS60209516A (en) 1985-10-22
NZ211078A (en) 1987-08-31
ZA851935B (en) 1985-10-30
PT80131A (en) 1985-04-01
SE8501312D0 (en) 1985-03-18
DK122285A (en) 1985-09-20
FI84023C (en) 1991-10-10
DE3509741A1 (en) 1985-09-26
KR850006136A (en) 1985-10-02
DK122285D0 (en) 1985-03-18
GR850688B (en) 1985-07-08
NO851022L (en) 1985-09-20
CA1238578A (en) 1988-06-28
AU571308B2 (en) 1988-04-14
NO170569C (en) 1992-11-04
PT80131B (en) 1987-10-20
IL74615A0 (en) 1985-06-30
NL8500739A (en) 1985-10-16
FI851040A0 (en) 1985-03-15
OA07968A (en) 1987-01-31
FR2561104B1 (en) 1988-04-08
GB2155789B (en) 1987-10-21
YU42085A (en) 1988-02-29
IT8519897A0 (en) 1985-03-14
IE850686L (en) 1985-09-19
ES8702140A1 (en) 1986-12-16
MY101916A (en) 1992-02-15
ES541370A0 (en) 1986-12-16
ATA81985A (en) 1990-12-15
DK164535C (en) 1992-11-30
FI851040L (en) 1985-09-20
AT392904B (en) 1991-07-10
IE58340B1 (en) 1993-09-08
NO170569B (en) 1992-07-27
SE8501312L (en) 1985-09-20
IT1187640B (en) 1987-12-23
DK164535B (en) 1992-07-13
YU45243B (en) 1992-05-28

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: BRISTOL-MYERS CY

Effective date: 19940331