BE890418A - Nouveau derive de benzanilide doue d'activite anti-arythmique, son procede de preparation et composition pharmaceutique le contenant - Google Patents

Nouveau derive de benzanilide doue d'activite anti-arythmique, son procede de preparation et composition pharmaceutique le contenant

Info

Publication number
BE890418A
BE890418A BE0/206007A BE206007A BE890418A BE 890418 A BE890418 A BE 890418A BE 0/206007 A BE0/206007 A BE 0/206007A BE 206007 A BE206007 A BE 206007A BE 890418 A BE890418 A BE 890418A
Authority
BE
Belgium
Prior art keywords
preparation
pharmaceutical composition
composition containing
same
arrhythmic activity
Prior art date
Application number
BE0/206007A
Other languages
English (en)
Inventor
R F Mayol
R E Gammans
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of BE890418A publication Critical patent/BE890418A/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Dérivé de benzanilide nouveau, à savoir le 4-hydroxy-3-méthoxy-N-(2-(2-(1-méthyl-2-pipéridinyl)éthyl)phényl)benzamide de formule (I). Le composé de l'invention est un agent doué d'activité anti-arythmique, de toxicité relativement faible et à durée d'action prolongée. La plage posologique normale va de 0,01 à 20 mg/kg.
BE0/206007A 1980-09-18 1981-09-18 Nouveau derive de benzanilide doue d'activite anti-arythmique, son procede de preparation et composition pharmaceutique le contenant BE890418A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/188,184 US4332803A (en) 1980-09-18 1980-09-18 Benzanilide derivative

Publications (1)

Publication Number Publication Date
BE890418A true BE890418A (fr) 1982-03-18

Family

ID=22692080

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/206007A BE890418A (fr) 1980-09-18 1981-09-18 Nouveau derive de benzanilide doue d'activite anti-arythmique, son procede de preparation et composition pharmaceutique le contenant

Country Status (25)

Country Link
US (1) US4332803A (fr)
JP (1) JPS5782368A (fr)
AR (1) AR227065A1 (fr)
AT (1) AT378181B (fr)
AU (1) AU526825B2 (fr)
BE (1) BE890418A (fr)
CA (1) CA1183537A (fr)
CH (2) CH650497A5 (fr)
CY (2) CY1370A (fr)
DE (2) DE3153300C2 (fr)
DK (1) DK152121C (fr)
FI (1) FI66597C (fr)
FR (1) FR2494267B1 (fr)
GB (2) GB2084570B (fr)
GR (1) GR75788B (fr)
HK (2) HK5388A (fr)
IE (1) IE51584B1 (fr)
IT (1) IT1209900B (fr)
KE (2) KE3717A (fr)
LU (1) LU83644A1 (fr)
NL (1) NL8104261A (fr)
SE (1) SE445215B (fr)
SG (1) SG30187G (fr)
YU (1) YU42425B (fr)
ZA (1) ZA816348B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4618680A (en) * 1980-09-18 1986-10-21 Mead Johnson & Company Benzanilide derivative

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931195A (en) * 1971-03-03 1976-01-06 Mead Johnson & Company Substituted piperidines
CA961038A (en) * 1971-03-03 1975-01-14 Joseph L. Minielli Substituted piperidines

Also Published As

Publication number Publication date
DK412881A (da) 1982-03-19
AT378181B (de) 1985-06-25
SE8105538L (sv) 1982-03-19
LU83644A1 (fr) 1982-04-14
YU219281A (en) 1984-02-29
GB2084570B (en) 1984-09-05
ZA816348B (en) 1982-09-29
FI812873L (fi) 1982-03-19
YU42425B (en) 1988-08-31
GR75788B (fr) 1984-08-02
IT8149311A0 (it) 1981-09-17
AU7518181A (en) 1982-03-25
CY1370A (en) 1987-08-07
GB2144050B (en) 1985-09-11
CH650497A5 (de) 1985-07-31
CA1183537A (fr) 1985-03-05
FI66597B (fi) 1984-07-31
DK152121B (da) 1988-02-01
JPS5782368A (en) 1982-05-22
CY1377A (en) 1987-08-07
AU526825B2 (en) 1983-02-03
DK152121C (da) 1988-06-20
AR227065A1 (es) 1982-09-15
GB8402839D0 (en) 1984-03-07
SE445215B (sv) 1986-06-09
US4332803A (en) 1982-06-01
FI66597C (fi) 1984-11-12
KE3716A (en) 1987-04-16
FR2494267B1 (fr) 1986-06-27
KE3717A (en) 1987-04-16
HK5388A (en) 1988-01-29
DE3153300C2 (de) 1987-03-19
HK4488A (en) 1988-01-29
ATA403781A (de) 1984-11-15
IT1209900B (it) 1989-08-30
DE3137084C2 (de) 1986-04-10
GB2144050A (en) 1985-02-27
FR2494267A1 (fr) 1982-05-21
NL8104261A (nl) 1982-04-16
GB2084570A (en) 1982-04-15
IE51584B1 (en) 1987-01-21
DE3137084A1 (de) 1982-05-13
CH651932A5 (de) 1985-10-15
SG30187G (en) 1987-07-17
IE812160L (en) 1982-03-18
JPH0256351B2 (fr) 1990-11-29

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: BRISTOL-MYERS CY

Effective date: 19930930