BE885894A - (alkyl-4 aroyl-4 piperidino)-4 butyrophenones, procedes et intermediaires pour leur preparation et compositions therapeutiques les contenant - Google Patents

(alkyl-4 aroyl-4 piperidino)-4 butyrophenones, procedes et intermediaires pour leur preparation et compositions therapeutiques les contenant

Info

Publication number
BE885894A
BE885894A BE0/202608A BE202608A BE885894A BE 885894 A BE885894 A BE 885894A BE 0/202608 A BE0/202608 A BE 0/202608A BE 202608 A BE202608 A BE 202608A BE 885894 A BE885894 A BE 885894A
Authority
BE
Belgium
Prior art keywords
butyrophenones
aroyl
piperidino
intermediates
alkyl
Prior art date
Application number
BE0/202608A
Other languages
English (en)
French (fr)
Inventor
A Carr
R Farr
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of BE885894A publication Critical patent/BE885894A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
BE0/202608A 1979-10-27 1980-10-27 (alkyl-4 aroyl-4 piperidino)-4 butyrophenones, procedes et intermediaires pour leur preparation et compositions therapeutiques les contenant BE885894A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8894279A 1979-10-27 1979-10-27

Publications (1)

Publication Number Publication Date
BE885894A true BE885894A (fr) 1981-02-16

Family

ID=22214421

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/202608A BE885894A (fr) 1979-10-27 1980-10-27 (alkyl-4 aroyl-4 piperidino)-4 butyrophenones, procedes et intermediaires pour leur preparation et compositions therapeutiques les contenant

Country Status (12)

Country Link
JP (1) JPS5673061A (nl)
AU (1) AU6369480A (nl)
BE (1) BE885894A (nl)
CA (1) CA1148162A (nl)
DE (1) DE3039974A1 (nl)
ES (1) ES8201550A1 (nl)
FR (1) FR2468592A1 (nl)
GB (1) GB2061937A (nl)
IL (1) IL61340A0 (nl)
IT (1) IT1146198B (nl)
NL (1) NL8005890A (nl)
ZA (1) ZA806501B (nl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008074703A1 (en) * 2006-12-19 2008-06-26 F. Hoffmann-La Roche Ag Heteroaryl pyrrolidinyl and piperidinyl ketone derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE713746C (de) * 1939-03-31 1941-11-18 I G Farbenindustrie Akt Ges Verfahren zur Darstellung von 4-Arylpiperidyl-4-ketonen
US3080372A (en) * 1960-03-25 1963-03-05 Res Lab Dr C Janssen 1-aroylalkyl-4-arylpiperidine derivatives
CH492709A (de) * 1968-01-11 1970-06-30 Geigy Ag J R Verfahren zur Herstellung von neuen Piperidinderivaten
CH498836A (de) * 1968-12-20 1970-11-15 Geigy Ag J R Verfahren zur Herstellung von neuen Piperidinderivaten
US3852455A (en) * 1970-11-27 1974-12-03 Richardson Merrell Inc 4-{8 4({60 hydroxybenzyl)piperidino{9 -4-fluorobutyrophenone derivatives as tranquilizers
ZA717147B (en) * 1970-11-27 1972-07-26 Richardson Merrell Inc 4-(4-(alpha-hydroxybenzyl)piperidino)-4'-fluorobutyrophenone derivatives
US3888867A (en) * 1972-05-03 1975-06-10 Richardson Merrell Inc 4-(4-(alpha-hydroxybenzyl)piperidino)4'-fluorobutyrophenone derivatives
US4101662A (en) * 1973-05-03 1978-07-18 A. H. Robins Company, Incorporated Method for inhibiting emesis and compositions therefor
SE7409245L (nl) * 1973-07-19 1975-01-20 Robins Co Inc A H
GB1535791A (en) * 1975-05-07 1978-12-13 Ferrosan Ab Derivatives of 4-piperidinol
CH602642A5 (nl) * 1975-11-14 1978-07-31 Orgamol Sa
US4335127A (en) * 1979-01-08 1982-06-15 Janssen Pharmaceutica, N.V. Piperidinylalkyl quinazoline compounds, composition and method of use

Also Published As

Publication number Publication date
FR2468592A1 (fr) 1981-05-08
CA1148162A (en) 1983-06-14
FR2468592B1 (nl) 1983-08-05
IT1146198B (it) 1986-11-12
IT8049998A0 (it) 1980-10-24
JPS5673061A (en) 1981-06-17
ES496204A0 (es) 1981-12-01
IL61340A0 (en) 1980-12-31
ES8201550A1 (es) 1981-12-01
NL8005890A (nl) 1981-04-29
DE3039974A1 (de) 1981-05-07
ZA806501B (en) 1981-10-28
GB2061937A (en) 1981-05-20
AU6369480A (en) 1981-04-30

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: RICHARDSON-MERRELL INC.

Effective date: 19931031