BE878514A - Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne - Google Patents

Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne

Info

Publication number
BE878514A
BE878514A BE0/196949A BE196949A BE878514A BE 878514 A BE878514 A BE 878514A BE 0/196949 A BE0/196949 A BE 0/196949A BE 196949 A BE196949 A BE 196949A BE 878514 A BE878514 A BE 878514A
Authority
BE
Belgium
Prior art keywords
disubstitution
cephem
positions
preparation
carboxylic acid
Prior art date
Application number
BE0/196949A
Other languages
English (en)
French (fr)
Inventor
T Takaya
T Masugi
H Takasugi
H Kochi
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Priority to US06/077,557 priority Critical patent/US4304770A/en
Publication of BE878514A publication Critical patent/BE878514A/fr
Priority to US06/296,117 priority patent/US4493833A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
BE0/196949A 1976-04-12 1979-08-30 Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne BE878514A (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US06/077,557 US4304770A (en) 1976-04-12 1979-09-21 Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof
US06/296,117 US4493833A (en) 1976-04-12 1981-08-25 Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7835435 1978-09-04

Publications (1)

Publication Number Publication Date
BE878514A true BE878514A (fr) 1980-02-29

Family

ID=10499419

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/196949A BE878514A (fr) 1976-04-12 1979-08-30 Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne

Country Status (8)

Country Link
JP (1) JPS5535096A (nl)
BE (1) BE878514A (nl)
CH (1) CH643849A5 (nl)
DE (1) DE2935232A1 (nl)
ES (2) ES483839A1 (nl)
FR (1) FR2434810A1 (nl)
NL (1) NL7906624A (nl)
SE (1) SE7907320L (nl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5585594A (en) * 1978-11-13 1980-06-27 Fujisawa Pharmaceut Co Ltd Cephem compound and their preparation
DE2945248A1 (de) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
US4331666A (en) * 1979-05-11 1982-05-25 Farmitalia Carlo Erba S.P.A. 3-[(8-Carboxy-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyimino-acetamido]-3-cephem-4-carboxylic acid
JPS56131591A (en) * 1980-02-20 1981-10-15 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, preparation thereof and preventing agent and remedy for microbism containing the same as active consitutent
JPS57131794A (en) * 1980-12-31 1982-08-14 Fujisawa Pharmaceut Co Ltd Novel cephem compound or salt thereof, preparation of the same and preventing agent and remedy for microbism containing the same as active constituent
JPS5849382A (ja) * 1981-09-18 1983-03-23 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
JPS5874680A (ja) * 1981-10-01 1983-05-06 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
US4499088A (en) * 1983-01-04 1985-02-12 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
DE2760484C2 (nl) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
FR2381053A1 (fr) * 1977-02-18 1978-09-15 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
ZA781502B (en) * 1977-03-14 1979-09-26 Fujisawa Pharmaceutical Co New cephem and cepham compounds and processes for preparation thereof
SE439312B (sv) * 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
FR2410655A1 (fr) * 1977-12-05 1979-06-29 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2387235A1 (fr) * 1978-01-23 1978-11-10 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne
DE2804040C3 (de) * 1978-01-31 1981-03-19 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von Cephemverbindungen
SE7901262L (sv) * 1978-02-15 1979-08-16 Fujisawa Pharmaceutical Co 3,7-disubstituerade 3-cefem-4-karboxylsyraforeningar och forfarande for deras framstellning
FR2432521A1 (fr) * 1978-03-31 1980-02-29 Roussel Uclaf Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2421907A1 (fr) * 1978-04-07 1979-11-02 Roussel Uclaf Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments
ZA792583B (en) * 1978-05-26 1980-07-30 Glaxo Group Ltd Cephalosporin antibiotics
NL7904125A (nl) * 1978-05-26 1979-11-28 Glaxo Group Ltd Cefalosporineverbindingen.
IT1116187B (it) * 1978-05-26 1986-02-10 Glaxo Group Ltd Antibiotici cefalosporinici composizioni che li contengono e relativo procedimento di produzione
GB1604722A (en) * 1978-05-26 1981-12-16 Glaxo Operations Ltd 7-(2-(2-amino-4-thiozolyl)-2-oxymino-acetamido)-cephem derivatives
AR229882A1 (es) * 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para preparar antibioticos de cefalosporina
DE2967356D1 (en) * 1978-07-17 1985-02-28 Fujisawa Pharmaceutical Co Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them
US4237128A (en) * 1979-04-12 1980-12-02 E. R. Squibb & Sons, Inc. 7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides
JPS5858353A (ja) * 1981-09-30 1983-04-06 ピ−シ−株式会社 強化コンクリ−ト構造体

Also Published As

Publication number Publication date
CH643849A5 (en) 1984-06-29
FR2434810A1 (fr) 1980-03-28
ES483839A1 (es) 1980-09-01
ES490888A0 (es) 1980-12-16
DE2935232A1 (de) 1980-03-13
JPS5535096A (en) 1980-03-11
SE7907320L (sv) 1980-03-05
ES8102142A1 (es) 1980-12-16
FR2434810B1 (nl) 1983-06-03
JPH0240678B2 (nl) 1990-09-12
NL7906624A (nl) 1980-03-06

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: FUJISAWA PHARMACEUTICAL CO. LTD

Effective date: 19860831