BE872886A - Steroides, leur preparation et leur utilisation therapeutique - Google Patents

Steroides, leur preparation et leur utilisation therapeutique

Info

Publication number
BE872886A
BE872886A BE1009202A BE1009202A BE872886A BE 872886 A BE872886 A BE 872886A BE 1009202 A BE1009202 A BE 1009202A BE 1009202 A BE1009202 A BE 1009202A BE 872886 A BE872886 A BE 872886A
Authority
BE
Belgium
Prior art keywords
steroids
preparation
therapeutic use
therapeutic
Prior art date
Application number
BE1009202A
Other languages
English (en)
French (fr)
Inventor
R G Christiansen
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of BE872886A publication Critical patent/BE872886A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0048—Alkynyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0057—Nitrogen and oxygen
    • C07J71/0063—Nitrogen and oxygen at position 2(3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
BE1009202A 1977-12-20 1978-12-20 Steroides, leur preparation et leur utilisation therapeutique BE872886A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/862,417 US4160027A (en) 1977-12-20 1977-12-20 Steroid cyanoketones and intermediates

Publications (1)

Publication Number Publication Date
BE872886A true BE872886A (fr) 1979-06-20

Family

ID=25338450

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1009202A BE872886A (fr) 1977-12-20 1978-12-20 Steroides, leur preparation et leur utilisation therapeutique

Country Status (27)

Country Link
US (1) US4160027A (cs)
JP (2) JPS5488253A (cs)
AR (1) AR222645A1 (cs)
AT (1) AT367070B (cs)
AU (1) AU518997B2 (cs)
BE (1) BE872886A (cs)
CA (1) CA1121340A (cs)
CH (1) CH637409A5 (cs)
DE (1) DE2855091A1 (cs)
DK (1) DK156727C (cs)
ES (1) ES476117A1 (cs)
FI (1) FI66010C (cs)
FR (1) FR2412569A1 (cs)
GB (2) GB2010278B (cs)
HK (1) HK89287A (cs)
IE (1) IE48076B1 (cs)
IL (1) IL56076A (cs)
IT (1) IT1195258B (cs)
LU (1) LU80673A1 (cs)
MX (1) MX5535E (cs)
NL (1) NL190848C (cs)
NO (1) NO151467C (cs)
NZ (1) NZ189035A (cs)
PH (2) PH14778A (cs)
PT (1) PT68926A (cs)
SE (1) SE433221B (cs)
ZA (1) ZA786746B (cs)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4349474A (en) * 1981-07-27 1982-09-14 G. D. Searle & Co. 2-Cyanosteroids
JPS5995300A (ja) * 1982-11-02 1984-06-01 スタ−リング・ドラッグ・インコ−ポレ−テッド コントロ−ルされた粒度の２−シアノ−４，５−エポキシ−３−オキソ−ステロイド類およびそれらの組成物
DK23984A (da) * 1983-02-11 1984-08-12 Hoffmann La Roche D-homosteroider
US4459235A (en) * 1983-03-03 1984-07-10 G. D. Searle & Co. 2-Cyanosteroids
GB8328929D0 (en) * 1983-10-29 1983-11-30 Sterwin Ag Steroid compounds
GB8404980D0 (en) * 1984-02-25 1984-03-28 Sterwin Ag Steroid compound
DE3531903A1 (de) * 1985-09-05 1987-03-12 Schering Ag Oxytocin und antigestagen zur einleitung der geburt bzw. zum therapeutischen abbruch der graviditaet
US4755595A (en) * 1985-11-01 1988-07-05 Sterling Drug Inc. Enhanced production of 4,5-unsaturated steroids utilizing methanol solvation
US4870068A (en) * 1986-05-22 1989-09-26 Sterling Drug Inc. Method of regulating fertility in swine using epostane
US4833133A (en) * 1986-05-22 1989-05-23 Sterling Drug Inc. Method of regulating fertility in cattle using epostane
US5795881A (en) * 1987-06-16 1998-08-18 Schering Aktiengesellschaft Combined use of an antigestagen and a progesterone synthesis inhibitor of the trilostane and epostane type
US5215978A (en) * 1989-06-16 1993-06-01 The Upjohn Company Method of enhancing egg laying in turkeys using epostane
JPH0538929A (ja) * 1991-08-02 1993-02-19 Mitsubishi Heavy Ind Ltd 車両用空気調和装置
GB2375958B (en) * 2001-04-09 2005-03-02 George Margetts The use of steroids to lower the levels of cortisol
GB2414238B (en) * 2004-05-22 2006-12-13 Stegram Pharmaceuticals Ltd Method for the preparation of trilostane
CN101282646B (zh) * 2005-07-12 2013-03-27 Dmi生物科学公司 治疗疾病的方法和产品
PT2554174E (pt) * 2009-06-22 2015-12-15 Ampio Pharmaceuticals Inc Método para o tratamento de doenças
AU2010264525B2 (en) * 2009-06-22 2015-04-02 Ampio Pharmaceuticals, Inc. Methods and products for treatment of diseases
EA201500752A1 (ru) 2012-12-19 2016-05-31 Ампио Фармасьютикалс, Инк. Способ лечения заболеваний

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3296255A (en) * 1963-11-29 1967-01-03 Sterling Drug Inc 2-cyano steroids
US3980638A (en) * 1974-09-20 1976-09-14 The Upjohn Company Testosterone derivatives
US4062954A (en) * 1976-12-27 1977-12-13 Sterling Drug Inc. Process for using a steroid compound

Also Published As

Publication number Publication date
PT68926A (en) 1979-01-01
AT367070B (de) 1982-05-25
GB2010278A (en) 1979-06-27
GB2088878B (en) 1983-01-19
IT1195258B (it) 1988-10-12
IE48076B1 (en) 1984-09-19
IL56076A (en) 1983-06-15
CH637409A5 (fr) 1983-07-29
FI783901A (fi) 1979-06-21
PH16835A (en) 1984-03-15
JPS6361314B2 (cs) 1988-11-28
AU518997B2 (en) 1981-10-29
NO784281L (no) 1979-06-21
DE2855091A1 (de) 1979-06-28
JPS6220998B2 (cs) 1987-05-11
NO151467B (no) 1985-01-02
DK156727C (da) 1990-03-12
ATA888578A (de) 1981-10-15
FI66010B (fi) 1984-04-30
DK156727B (da) 1989-09-25
FI66010C (fi) 1984-08-10
ES476117A1 (es) 1979-11-16
IL56076A0 (en) 1979-01-31
SE433221B (sv) 1984-05-14
AR222645A1 (es) 1981-06-15
AU4208978A (en) 1979-06-28
HK89287A (en) 1987-12-11
DE2855091C2 (cs) 1988-12-22
JPS62142198A (ja) 1987-06-25
SE7813067L (sv) 1979-06-21
FR2412569A1 (fr) 1979-07-20
FR2412569B1 (cs) 1982-05-28
ZA786746B (en) 1979-11-28
JPS5488253A (en) 1979-07-13
GB2088878A (en) 1982-06-16
GB2010278B (en) 1982-10-20
IT7831011A0 (it) 1978-12-19
NZ189035A (en) 1980-08-26
NL190848B (nl) 1994-04-18
PH14778A (en) 1981-12-09
NO151467C (no) 1985-04-17
IE782492L (en) 1979-06-20
LU80673A1 (fr) 1979-07-20
NL7812309A (nl) 1979-06-22
DK569678A (da) 1979-06-21
US4160027A (en) 1979-07-03
NL190848C (nl) 1994-09-16
CA1121340A (en) 1982-04-06
MX5535E (es) 1983-09-27

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Legal Events

Date Code Title Description
CH Change of patent owner
RE20 Patent expired

Owner name: S.A. SANOFI

Effective date: 19981220