BE847234A - Nouveaux composes pour combattre les leucemies et les tumeurs malignes, - Google Patents

Nouveaux composes pour combattre les leucemies et les tumeurs malignes,

Info

Publication number
BE847234A
BE847234A BE171474A BE171474A BE847234A BE 847234 A BE847234 A BE 847234A BE 171474 A BE171474 A BE 171474A BE 171474 A BE171474 A BE 171474A BE 847234 A BE847234 A BE 847234A
Authority
BE
Belgium
Prior art keywords
fight
leukemia
new compounds
malignant tumors
malignant
Prior art date
Application number
BE171474A
Other languages
English (en)
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE847234A publication Critical patent/BE847234A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BE171474A 1975-10-16 1976-10-13 Nouveaux composes pour combattre les leucemies et les tumeurs malignes, BE847234A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB42509/75A GB1561290A (en) 1975-10-16 1975-10-16 Pyrimid - 2 - ones

Publications (1)

Publication Number Publication Date
BE847234A true BE847234A (fr) 1977-04-13

Family

ID=10424751

Family Applications (1)

Application Number Title Priority Date Filing Date
BE171474A BE847234A (fr) 1975-10-16 1976-10-13 Nouveaux composes pour combattre les leucemies et les tumeurs malignes,

Country Status (14)

Country Link
US (1) US4395406A (en:Method)
JP (1) JPS5253869A (en:Method)
BE (1) BE847234A (en:Method)
CA (1) CA1086736A (en:Method)
CH (3) CH634308A5 (en:Method)
DE (1) DE2646676A1 (en:Method)
DK (1) DK144525C (en:Method)
FR (1) FR2327765A1 (en:Method)
GB (1) GB1561290A (en:Method)
IE (1) IE44431B1 (en:Method)
LU (1) LU75994A1 (en:Method)
NL (1) NL7611415A (en:Method)
NO (1) NO151040C (en:Method)
SE (1) SE439305B (en:Method)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1582884A (en) * 1977-05-19 1981-01-14 Beecham Group Ltd Clavulanic acid derivatives their preparation and use
ZA804670B (en) * 1979-08-03 1981-07-29 Beecham Group Ltd Derivatives of clavulanic acid, a process for their preparation and their use
ES8205399A1 (es) * 1980-01-07 1982-06-01 Nyegaard & Co As Un procedimiento para la preparacion de 5-halo-pirimidin-2- onas
ES8205782A1 (es) 1980-01-10 1982-08-01 Nyegaard & Co As Procedimiento para la preparacion de pirimidin-2-sulfuros y sus s-oxidos
NZ197714A (en) * 1980-07-15 1984-11-09 Glaxo Group Ltd Substituted pyrimidin-2-ones and pharmaceutical compositions
NZ197715A (en) * 1980-07-15 1984-12-14 Glaxo Group Ltd Substituted pyrimin-2-ones and pharmaceutical compositions
DE3169452D1 (en) * 1980-12-09 1985-04-25 Beecham Group Plc Derivatives of clavulanic acid, their preparation and their use
NZ199200A (en) * 1980-12-23 1984-07-31 Beecham Group Ltd Clavulanic acid derivatives and pharmaceutical compositions
CA1180710A (en) * 1981-01-09 1985-01-08 Tore Benneche Substituted pyrimidin-2-ones and the salts thereof
DE3272892D1 (en) * 1981-09-11 1986-10-02 Nyegaard & Co As Substituted pyrimid-2-ones, the salts thereof, processes for their preparation and pharmaceutical compositions containing them
US4782142A (en) * 1982-01-05 1988-11-01 The Research Foundation Of State University Of New York Novel 5-substituted 2-pyrimidinone nucleosides and methods of use
ATE27153T1 (de) * 1982-02-24 1987-05-15 Nycomed As Substituierte pyrimidin-2-one und deren salze.
CA1275410C (en) * 1986-03-14 1990-10-23 Karnail S. Atwal 1,2,3,4-tetrahydro-6-substituted-4-aryl(or heterocyclo) -3-substituted-2-thioxo(or oxo)-5- pyrimidinecarboxylic acids and esters
GB8706176D0 (en) * 1987-03-16 1987-04-23 Wellcome Found Therapeutic nucleosides
DE68920880D1 (de) * 1988-07-18 1995-03-09 Yamasa Shoyu Kk 1-amino-5-halogenouracile, verfahren zu deren herstellung und diese enthaltende cns-depressiva.
GB9026114D0 (en) * 1990-11-30 1991-01-16 Norsk Hydro As New compounds
WO1997014709A1 (en) * 1995-10-13 1997-04-24 F. Hoffmann-La Roche Ag Antisense oligomers
EP0882734B1 (en) * 1997-06-02 2009-08-26 F. Hoffmann-La Roche Ag 5'-Deoxy-cytidine derivatives
NZ330360A (en) * 1997-06-02 1999-03-29 Hoffmann La Roche 5'-deoxy-cytidine derivatives, their manufacture and use as antitumoral agents
US6005098A (en) * 1998-02-06 1999-12-21 Hoffmann-La Roche Inc. 5'deoxycytidine derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3317532A (en) * 1964-11-19 1967-05-02 Hoffmann La Roche Derivatives of pyrimidine
DE2032559A1 (de) * 1970-06-27 1972-01-13 Schering Ag Berlin Und Bergkamen, 1000 Berlin N-Substituierte Amide und Lactame
US3833586A (en) * 1971-03-25 1974-09-03 Morton Norwich Products Inc 1-(substituted benzyl)-2-(1h)pyrimidones and 1-(substituted benzyl)tetrahydro-2-(1h)pyrimidones
DE2440677A1 (de) * 1974-08-24 1976-03-04 Bayer Ag Pyrimidinylthionophosphonsaeureester, verfahren zu ihrer herstellung und ihre verwendung als insektizide, akarizide und nematizide
DE2450951A1 (de) * 1974-10-26 1976-05-06 Bayer Ag Pyrimidinyl(thiono)(thiol)phosphor (phosphon)-saeureester bzw. -esteramide, verfahren zu ihrer herstellung und ihre verwendung als insektizide, akarizide und nematizide
US4003900A (en) * 1976-03-11 1977-01-18 Morton-Norwich Products, Inc. 1-Benzyl-5-chloro-2-(1H)-pyrimidone

Also Published As

Publication number Publication date
DE2646676C2 (en:Method) 1987-06-19
NO151040C (no) 1985-01-30
DK462376A (da) 1977-04-17
CA1086736A (en) 1980-09-30
LU75994A1 (en:Method) 1977-05-11
FR2327765A1 (fr) 1977-05-13
NO151040B (no) 1984-10-22
DK144525C (da) 1982-10-18
FR2327765B1 (en:Method) 1981-11-20
GB1561290A (en) 1980-02-20
CH634309A5 (de) 1983-01-31
JPS5253869A (en) 1977-04-30
CH634310A5 (de) 1983-01-31
IE44431B1 (en) 1981-12-02
US4395406A (en) 1983-07-26
DE2646676A1 (de) 1977-04-28
IE44431L (en) 1977-04-16
CH634308A5 (de) 1983-01-31
NO763533L (en:Method) 1977-04-19
NL7611415A (nl) 1977-04-19
SE439305B (sv) 1985-06-10
DK144525B (da) 1982-03-22
SE7611493L (sv) 1977-04-17

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: NYEGAARD & CO. A/S

Effective date: 19871031