BE833245A - Procede de preparation de la cefazoline - Google Patents
Procede de preparation de la cefazolineInfo
- Publication number
- BE833245A BE833245A BE1006874A BE1006874A BE833245A BE 833245 A BE833245 A BE 833245A BE 1006874 A BE1006874 A BE 1006874A BE 1006874 A BE1006874 A BE 1006874A BE 833245 A BE833245 A BE 833245A
- Authority
- BE
- Belgium
- Prior art keywords
- cefazoline
- preparing
- preparing cefazoline
- Prior art date
Links
- MLYYVTUWGNIJIB-BXKDBHETSA-N cefazolin Chemical compound S1C(C)=NN=C1SCC1=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CN3N=NN=C3)[C@H]2SC1 MLYYVTUWGNIJIB-BXKDBHETSA-N 0.000 title 1
- 229960001139 cefazolin Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/505,304 US3954745A (en) | 1974-09-12 | 1974-09-12 | Process for preparing cefazolin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE833245A true BE833245A (fr) | 1976-03-10 |
Family
ID=24009783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE1006874A BE833245A (fr) | 1974-09-12 | 1975-09-10 | Procede de preparation de la cefazoline |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3954745A (de) |
| JP (1) | JPS5148688A (de) |
| BE (1) | BE833245A (de) |
| CA (1) | CA1052769A (de) |
| CH (1) | CH615184A5 (de) |
| DE (1) | DE2540374C2 (de) |
| FR (1) | FR2284608A1 (de) |
| GB (1) | GB1516863A (de) |
| IE (1) | IE41280B1 (de) |
| IL (1) | IL47856A (de) |
| NL (1) | NL180318C (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR223653A1 (es) * | 1977-09-27 | 1981-09-15 | Toyama Chemical Co Ltd | Procedimiento de preparacion del acido 7-(d(-)-alpha-(4-etil-2,3-dioxo-1-piperazinocarboxamido)-alpha-(4-hidroxifenil)acetamido)-3-(5-(1-metil-1,2,3,4-tetrazolil)tiometil)-delta3-cefem-4-carboxilico y su producto de adicion con n,n-dimetilacetamida |
| IT1180207B (it) * | 1984-07-30 | 1987-09-23 | Istituto Biochimico Italiano | Procedimento per la preparazione, con resa e purezza elevate, di antibiotici beta-lattamici |
| JPS63287565A (ja) * | 1987-05-19 | 1988-11-24 | 小松電子金属株式会社 | 半導体用シリコンの破砕方法 |
| IT1265341B1 (it) * | 1993-07-16 | 1996-11-22 | Farmabios Srl | Procedimento per la preparazione di cefalosporine |
| JPH10101679A (ja) * | 1996-10-02 | 1998-04-21 | Otsuka Chem Co Ltd | セファゾリンの製造法 |
| EP0953569A1 (de) * | 1998-04-29 | 1999-11-03 | Gist-Brocades B.V. | Herstellung von Beta-Laktamantibiotika in Anwesenheit von Harnstoff oder Amid |
| JP2004538265A (ja) | 2001-04-19 | 2004-12-24 | ビオフェルマ ムルシア，エス．アー． | α−ケト酸誘導体を使用して３−セファロスポラン酸誘導体を製造する方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1104937A (en) * | 1964-05-28 | 1968-03-06 | Glaxo Lab Ltd | Improvements in or relating to the acylation of 7-aminocephalosporanic acid and derivatives thereof |
| CH527215A (de) * | 1967-04-15 | 1972-08-31 | Fujisawa Pharmaceutical Co | Verfahren zur Herstellung von 3,7-disubstituierten Cephalosporinderivaten |
| BE793191A (fr) * | 1971-12-28 | 1973-06-22 | Toyama Chemical Co Ltd | Procede pour produire des acides 7-acylamido-3-cephem-4- carboxyliques |
-
1974
- 1974-09-12 US US05/505,304 patent/US3954745A/en not_active Expired - Lifetime
-
1975
- 1975-07-25 CA CA232,267A patent/CA1052769A/en not_active Expired
- 1975-07-28 IE IE1685/75A patent/IE41280B1/xx unknown
- 1975-08-03 IL IL47856A patent/IL47856A/xx unknown
- 1975-08-29 JP JP50105546A patent/JPS5148688A/ja active Granted
- 1975-09-01 GB GB35926/75A patent/GB1516863A/en not_active Expired
- 1975-09-10 BE BE1006874A patent/BE833245A/xx not_active IP Right Cessation
- 1975-09-10 FR FR7527773A patent/FR2284608A1/fr active Granted
- 1975-09-10 DE DE2540374A patent/DE2540374C2/de not_active Expired
- 1975-09-11 NL NLAANVRAGE7510738,A patent/NL180318C/xx not_active IP Right Cessation
- 1975-09-12 CH CH1184975A patent/CH615184A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2284608B1 (de) | 1978-04-07 |
| DE2540374C2 (de) | 1984-03-01 |
| FR2284608A1 (fr) | 1976-04-09 |
| IL47856A0 (en) | 1975-11-25 |
| IE41280L (en) | 1976-03-12 |
| CA1052769A (en) | 1979-04-17 |
| CH615184A5 (de) | 1980-01-15 |
| JPH0114239B2 (de) | 1989-03-10 |
| NL180318C (nl) | 1987-02-02 |
| GB1516863A (en) | 1978-07-05 |
| NL180318B (nl) | 1986-09-01 |
| DE2540374A1 (de) | 1976-03-25 |
| JPS5148688A (en) | 1976-04-26 |
| IL47856A (en) | 1978-04-30 |
| IE41280B1 (en) | 1979-11-21 |
| NL7510738A (nl) | 1976-03-16 |
| US3954745A (en) | 1976-05-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE20 | Patent expired |
Owner name: ELI LILLY AND CY Effective date: 19950910 |