BE818729A - Poudre de sitosterols pharmaceutique dispersible et son procedede preparation - Google Patents

Poudre de sitosterols pharmaceutique dispersible et son procedede preparation

Info

Publication number
BE818729A
BE818729A BE1006118A BE1006118A BE818729A BE 818729 A BE818729 A BE 818729A BE 1006118 A BE1006118 A BE 1006118A BE 1006118 A BE1006118 A BE 1006118A BE 818729 A BE818729 A BE 818729A
Authority
BE
Belgium
Prior art keywords
sitosterols
powder
preparation
dispersible pharmaceutical
dispersible
Prior art date
Application number
BE1006118A
Other languages
English (en)
French (fr)
Inventor
A L Thakkar
E R Diller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE818729A publication Critical patent/BE818729A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BE1006118A 1973-08-13 1974-08-12 Poudre de sitosterols pharmaceutique dispersible et son procedede preparation BE818729A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US387999A US3881005A (en) 1973-08-13 1973-08-13 Pharmaceutical dispersible powder of sitosterols and a method for the preparation thereof

Publications (1)

Publication Number Publication Date
BE818729A true BE818729A (fr) 1975-02-12

Family

ID=23532208

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1006118A BE818729A (fr) 1973-08-13 1974-08-12 Poudre de sitosterols pharmaceutique dispersible et son procedede preparation

Country Status (14)

Country Link
US (1) US3881005A (is")
JP (1) JPS5048115A (is")
AR (1) AR202034A1 (is")
AT (1) ATA655474A (is")
AU (1) AU7155674A (is")
BE (1) BE818729A (is")
DD (1) DD112899A5 (is")
DE (1) DE2437845A1 (is")
DK (1) DK427674A (is")
FR (1) FR2240717B1 (is")
IL (1) IL45311A0 (is")
NL (1) NL7410862A (is")
SE (1) SE7410331L (is")
ZA (1) ZA744587B (is")

Families Citing this family (68)

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JPS51139613A (en) * 1975-05-24 1976-12-02 Nippon Shinyaku Co Ltd An absorbable non-crystalline sterol glycoside monopalmitate ester and a method for preparing its pharmaceutical
JPS5266616A (en) * 1975-11-29 1977-06-02 Sawai Seiyaku Kk Manufacturing of solidified oily liquid substance
US5270041A (en) * 1989-07-21 1993-12-14 Marigen S.A. Sterols, their fatty acid esters and glucosides; processes for their preparation; spontaneously dispersible agents containing these compounds, and their use for treatment of tumors
US5244887A (en) * 1992-02-14 1993-09-14 Straub Carl D Stanols to reduce cholesterol absorption from foods and methods of preparation and use thereof
AU7250694A (en) * 1993-06-25 1995-01-17 Biosphere Technologies Inc. Dietary supplement incorporating beta-sitosterol and pectin
US6936277B2 (en) * 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
US20030104035A1 (en) 1996-08-09 2003-06-05 Raisio Benecol Ltd. Stanol composition and the use thereof
FI105887B (fi) * 1996-09-27 2000-10-31 Suomen Sokeri Oy Elintarvike- ja terapeuttisiin sovelluksiin käyttökelpoiset, kasvisterolia sisältävät tuotteet, menetelmä niiden valmistamiseksi ja niiden käyttö
FI108110B (fi) * 1997-06-13 2001-11-30 Danisco Finland Oy Elintarvike- ja eläinravitsemusalalla käyttökelpoinen esiseos, menetelmä sen valmistamiseksi ja sen käyttö
US6423363B1 (en) † 1997-08-22 2002-07-23 Lipton, Division Of Conopco, Inc. Aqueous dispersion
US6110502A (en) * 1998-02-19 2000-08-29 Mcneil-Ppc, Inc. Method for producing water dispersible sterol formulations
IN185730B (is") * 1998-02-19 2001-04-14 Mcneil Ppc Inc
FR2775620B1 (fr) 1998-03-05 2002-04-19 Gervais Danone Sa Suspension homogene stable depourvue d'emulsifiant, son procede de preparation et son utilisation dans des compositions alimentaires
SE512958C2 (sv) 1998-04-30 2000-06-12 Triple Crown Ab Kolesterolsänkande komposition innehållande beta-sitosterol och/eller beta-sitostanol samt förfarande för dess framställning
US5932562A (en) * 1998-05-26 1999-08-03 Washington University Sitostanol formulation to reduce cholesterol absorption and method for preparing and use of same
US6123978A (en) 1998-08-31 2000-09-26 Mcneil-Ppc, Inc. Stable salad dressings
US6376481B2 (en) * 1998-09-02 2002-04-23 Mcneil-Ppc, Inc. Sterol esters in tableted solid dosage forms
US6242001B1 (en) 1998-11-30 2001-06-05 Mcneil-Ppc, Inc. Method for producing dispersible sterol and stanol compounds
US6113972A (en) * 1998-12-03 2000-09-05 Monsanto Co. Phytosterol protein complex
AU1995400A (en) * 1999-01-15 2000-08-01 Nutrahealth Ltd (Uk) Modified food products and beverages, and additives for food and beverages
AU2426500A (en) * 1999-02-03 2000-08-25 Forbes Medi-Tech Inc. Method of preparing microparticles of phytosterols or phytostanols
US6190720B1 (en) * 1999-06-15 2001-02-20 Opta Food Ingredients, Inc. Dispersible sterol compositions
IL147259A0 (en) * 1999-06-25 2002-08-14 Cognis Deutschland Gmbh Use of nanoscale sterols and sterol esters
US6391370B1 (en) * 1999-11-12 2002-05-21 Kraft Foods, Inc. Micromilling plant sterols and emulsifiers
US6677327B1 (en) 1999-11-24 2004-01-13 Archer-Daniels-Midland Company Phytosterol and phytostanol compositions
US6355274B1 (en) * 1999-12-15 2002-03-12 Mcneil-Ppc, Inc. Encapsulated long chain alcohols
US7232574B1 (en) 1999-12-15 2007-06-19 Mcneil-Ppc, Inc. Long chain alcohols provided in edible oils
US20030165572A1 (en) * 2000-09-01 2003-09-04 Nicolas Auriou Water-dispersible encapsulated sterols
GB0021498D0 (en) 2000-09-01 2000-10-18 Novartis Nutrition Ag New formulation
AU2005234649B2 (en) * 2000-09-01 2008-01-17 Forbes Medi-Tech, Inc. Water-dispersible encapsulated sterols
KR20020026053A (ko) 2000-09-30 2002-04-06 노승권 음료용 식물성 스테롤의 분산방법 및 이를 함유하는 음료
US6773733B2 (en) 2001-03-26 2004-08-10 Loders Croklaan Usa Llc Structured particulate systems
US20030003131A1 (en) * 2001-06-22 2003-01-02 Matthew Dyer Method for manufacture of free-flowing powder containing water-dispersible sterols
US7144595B2 (en) 2001-11-16 2006-12-05 Brandeis University Prepared foods containing triglyceride-recrystallized non-esterified phytosterols
ATE446013T1 (de) * 2001-11-16 2009-11-15 Univ Brandeis Fertignahrung, die aus triglyceriden umkristallisierte nichtveresterte phytosterole enthalten
FI117082B (fi) * 2002-02-08 2006-06-15 Raisio Yhtymae Oyj Esteröityjä kasvisteroleita sisältävä pastatuote
JP2005520508A (ja) * 2002-03-20 2005-07-14 ユージーン サイエンス インコーポレイテッド 植物ステロールと乳化剤の混合粉末及びその製造方法
AU2002241368B2 (en) * 2002-03-20 2009-07-09 Eugene Science Inc. Plant sterol-containing food, and method for preparing the same
US20040013708A1 (en) * 2002-04-10 2004-01-22 Goulson Melanie J. Aqueous dispersible steryl ester compositions
WO2003105611A2 (en) * 2002-06-12 2003-12-24 The Coca-Cola Company Beverages containing plant sterols
US7732000B2 (en) * 2002-06-20 2010-06-08 General Mills, Inc. Food intermediate having sequestered phytosteryl esters in a polysaccharide matrix
WO2005014158A1 (en) 2003-07-17 2005-02-17 Unilever N.V. Process for the preparation of an edible dispersion comprising oil and structuring agent
DE602005010972D1 (de) * 2004-01-30 2008-12-24 Unilever Nv Teilchenförmiges produkt, das phytosterole enthält, sowie nahrungsmittelzusammensetzungen, die dieses weissmittel enthalten
US8968768B2 (en) * 2004-03-29 2015-03-03 Wyeth Llc Phytosterol nutritional supplements
TR201909238T4 (tr) * 2004-03-29 2019-07-22 Wyeth Llc Multi-vitamin ve mineral besin takviyeleri.
US20060035009A1 (en) * 2004-08-10 2006-02-16 Kraft Foods Holdings, Inc. Compositions and processes for water-dispersible phytosterols and phytostanols
US20060034934A1 (en) * 2004-08-13 2006-02-16 Deguise Matthew L Agglomeration of sterol particles
BRPI0606545A2 (pt) 2005-02-17 2009-06-30 Unilever Nv dispersão comestìvel espalhável e seu processo de preparação
DE102005008445A1 (de) * 2005-02-24 2006-08-31 Cognis Ip Management Gmbh Zuckerhaltige Sterolfeststoffdispersionen
DE102005039836A1 (de) * 2005-08-23 2007-03-01 Cognis Ip Management Gmbh Sterolesterpulver
US7575768B2 (en) * 2005-09-07 2009-08-18 Brandeis University Dietary supplements and prepared foods containing triglyceride-recrystallized non-esterified phytosterols
KR20080108969A (ko) * 2005-12-20 2008-12-16 포비스 메디-테크 인코포레이티드 수성 상에 비에스테르화 파이토스테롤을 포함하는 에멀젼
US8309156B2 (en) * 2005-12-20 2012-11-13 Pharmachem Laboratories, Inc. Compositions comprising one or more phytosterols and/or phytostanols, or derivatives thereof, and high HLB emulsifiers
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EP1929884A1 (de) * 2006-12-04 2008-06-11 Cognis IP Management GmbH Verfahren zur Herstellung von Sterolformulierungen
US20090092727A1 (en) * 2007-10-04 2009-04-09 Daniel Perlman Water-dispersible phytosterol-surfactant conglomerate particles
US7790495B2 (en) * 2007-10-26 2010-09-07 International Business Machines Corporation Optoelectronic device with germanium photodetector
FI20085533A0 (fi) * 2008-06-02 2008-06-02 Raisio Nutrition Ltd Elintarvikekoostumus
US8273401B2 (en) * 2008-10-31 2012-09-25 Frito-Lay North America, Inc. Phytosterol/salt composition for topical application to food products
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AU2009328392B2 (en) 2008-12-19 2013-08-22 Upfield Europe B.V. Edible fat powders
US20110223312A1 (en) * 2009-11-30 2011-09-15 Daniel Perlman Triglyceride-encapsulated phytosterol microparticles dispersed in beverages
CA2802616C (en) 2010-06-22 2018-07-10 Unilever Plc Edible fat powders
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US8993035B2 (en) 2010-12-17 2015-03-31 Conopco, Inc. Edible water in oil emulsion
KR102063558B1 (ko) 2015-03-11 2020-02-11 티유비아이티에이케이 총 콜레스테롤 및 ldl 콜레스테롤 수준 저하용 수성 또는 분말 형태의 수 분산형 스테롤/스타놀이 강화된 폴리페놀이 풍부한 허브 차
IT201700066508A1 (it) * 2017-06-15 2018-12-15 Isagro Spa Sospensioni concentrate di fitosteroli e relativo processo di preparazione

Family Cites Families (2)

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DE1228029C2 (de) * 1964-05-09 1973-05-17 Merck Ag E Verfahren zur Herstellung von Tabletten durch Pressen von Pulvergemischen ohne vorhergehende Granulation
US3800038A (en) * 1972-04-21 1974-03-26 Biolog Concepts Inc Uterine administraton of eutectic solid solutions of steroid hormones in a steroidal lipid carrier

Also Published As

Publication number Publication date
AR202034A1 (es) 1975-05-09
ZA744587B (en) 1976-02-25
NL7410862A (nl) 1975-02-17
FR2240717B1 (is") 1977-11-04
DD112899A5 (is") 1975-05-12
DK427674A (is") 1975-04-21
FR2240717A1 (is") 1975-03-14
SE7410331L (is") 1975-02-14
JPS5048115A (is") 1975-04-30
DE2437845A1 (de) 1975-02-27
AU7155674A (en) 1976-01-29
IL45311A0 (en) 1974-10-22
US3881005A (en) 1975-04-29
ATA655474A (de) 1977-02-15

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