AR202034A1 - Procedimiento para preparar polvo farmaceutico dispersible para administracion oral de sitosteroles - Google Patents

Procedimiento para preparar polvo farmaceutico dispersible para administracion oral de sitosteroles

Info

Publication number
AR202034A1
AR202034A1 AR254972A AR25497274A AR202034A1 AR 202034 A1 AR202034 A1 AR 202034A1 AR 254972 A AR254972 A AR 254972A AR 25497274 A AR25497274 A AR 25497274A AR 202034 A1 AR202034 A1 AR 202034A1
Authority
AR
Argentina
Prior art keywords
sitosterols
procedure
oral administration
pharmaceutical powder
dispersible pharmaceutical
Prior art date
Application number
AR254972A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of AR202034A1 publication Critical patent/AR202034A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AR254972A 1973-08-13 1974-07-30 Procedimiento para preparar polvo farmaceutico dispersible para administracion oral de sitosteroles AR202034A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US387999A US3881005A (en) 1973-08-13 1973-08-13 Pharmaceutical dispersible powder of sitosterols and a method for the preparation thereof

Publications (1)

Publication Number Publication Date
AR202034A1 true AR202034A1 (es) 1975-05-09

Family

ID=23532208

Family Applications (1)

Application Number Title Priority Date Filing Date
AR254972A AR202034A1 (es) 1973-08-13 1974-07-30 Procedimiento para preparar polvo farmaceutico dispersible para administracion oral de sitosteroles

Country Status (14)

Country Link
US (1) US3881005A (es)
JP (1) JPS5048115A (es)
AR (1) AR202034A1 (es)
AT (1) ATA655474A (es)
AU (1) AU7155674A (es)
BE (1) BE818729A (es)
DD (1) DD112899A5 (es)
DE (1) DE2437845A1 (es)
DK (1) DK427674A (es)
FR (1) FR2240717B1 (es)
IL (1) IL45311A0 (es)
NL (1) NL7410862A (es)
SE (1) SE7410331L (es)
ZA (1) ZA744587B (es)

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US5244887A (en) * 1992-02-14 1993-09-14 Straub Carl D Stanols to reduce cholesterol absorption from foods and methods of preparation and use thereof
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US6936277B2 (en) * 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
US20030104035A1 (en) * 1996-08-09 2003-06-05 Raisio Benecol Ltd. Stanol composition and the use thereof
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FI108110B (fi) * 1997-06-13 2001-11-30 Danisco Finland Oy Elintarvike- ja eläinravitsemusalalla käyttökelpoinen esiseos, menetelmä sen valmistamiseksi ja sen käyttö
US6423363B1 (en) † 1997-08-22 2002-07-23 Lipton, Division Of Conopco, Inc. Aqueous dispersion
US6110502A (en) * 1998-02-19 2000-08-29 Mcneil-Ppc, Inc. Method for producing water dispersible sterol formulations
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FR2775620B1 (fr) * 1998-03-05 2002-04-19 Gervais Danone Sa Suspension homogene stable depourvue d'emulsifiant, son procede de preparation et son utilisation dans des compositions alimentaires
SE512958C2 (sv) 1998-04-30 2000-06-12 Triple Crown Ab Kolesterolsänkande komposition innehållande beta-sitosterol och/eller beta-sitostanol samt förfarande för dess framställning
US5932562A (en) * 1998-05-26 1999-08-03 Washington University Sitostanol formulation to reduce cholesterol absorption and method for preparing and use of same
US6123978A (en) * 1998-08-31 2000-09-26 Mcneil-Ppc, Inc. Stable salad dressings
US6376481B2 (en) 1998-09-02 2002-04-23 Mcneil-Ppc, Inc. Sterol esters in tableted solid dosage forms
US6242001B1 (en) 1998-11-30 2001-06-05 Mcneil-Ppc, Inc. Method for producing dispersible sterol and stanol compounds
US6113972A (en) * 1998-12-03 2000-09-05 Monsanto Co. Phytosterol protein complex
AU1995400A (en) * 1999-01-15 2000-08-01 Nutrahealth Ltd (Uk) Modified food products and beverages, and additives for food and beverages
PT1148793E (pt) * 1999-02-03 2003-12-31 Forbes Medi Tech Inc Metodo para a preparacao de microparticulas de fitoesterois ou fitoestanois
US6190720B1 (en) * 1999-06-15 2001-02-20 Opta Food Ingredients, Inc. Dispersible sterol compositions
JP2003516115A (ja) * 1999-06-25 2003-05-13 コグニス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ナノスケールステロールおよびステロールエステルの使用
US6391370B1 (en) * 1999-11-12 2002-05-21 Kraft Foods, Inc. Micromilling plant sterols and emulsifiers
US6677327B1 (en) * 1999-11-24 2004-01-13 Archer-Daniels-Midland Company Phytosterol and phytostanol compositions
US6355274B1 (en) * 1999-12-15 2002-03-12 Mcneil-Ppc, Inc. Encapsulated long chain alcohols
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US20030165572A1 (en) * 2000-09-01 2003-09-04 Nicolas Auriou Water-dispersible encapsulated sterols
AU2005234649B2 (en) * 2000-09-01 2008-01-17 Forbes Medi-Tech, Inc. Water-dispersible encapsulated sterols
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KR20020026053A (ko) 2000-09-30 2002-04-06 노승권 음료용 식물성 스테롤의 분산방법 및 이를 함유하는 음료
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US20030003131A1 (en) * 2001-06-22 2003-01-02 Matthew Dyer Method for manufacture of free-flowing powder containing water-dispersible sterols
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US7144595B2 (en) 2001-11-16 2006-12-05 Brandeis University Prepared foods containing triglyceride-recrystallized non-esterified phytosterols
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CN1297216C (zh) * 2002-03-20 2007-01-31 尤金科学(有限)公司 植物甾醇与乳化剂的混合粉末及其制备方法
US20050170064A1 (en) * 2002-03-20 2005-08-04 Eugene Science Inc. Plant sterol-containing food, and method for preparing the same
JP2005529109A (ja) * 2002-04-10 2005-09-29 カーギル，インコーポレイティド 水性分散性ステリル・エステル組成物
JP4773720B2 (ja) * 2002-06-12 2011-09-14 ザ・コカ−コーラ・カンパニー 植物ステロール含有飲料
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US8968768B2 (en) * 2004-03-29 2015-03-03 Wyeth Llc Phytosterol nutritional supplements
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US20060034934A1 (en) * 2004-08-13 2006-02-16 Deguise Matthew L Agglomeration of sterol particles
EP1885192B8 (en) * 2005-02-17 2015-05-13 Unilever N.V. Fat granules
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US20130266715A1 (en) 2010-12-17 2013-10-10 René Joachim Buter Process of compacting a microporous fat powder and compacted fat powder so obtained
JP6684290B2 (ja) 2015-03-11 2020-04-22 チュビタック （ターキー ビリムセル ヴィ テクノロジク アラスティルマ クルム）Ｔｕｂｉｔａｋ （Ｔｕｒｋｉｙｅ Ｂｉｌｉｍｓｅｌ Ｖｅ Ｔｅｋｎｏｌｏｊｉｋ Ａｒａｓｔｉｒｍａ Ｋｕｒｕｍｕ） 総コレステロール値およびｌｄｌコレステロール値を低下させる水性形態または粉末形態の水分散性ステロール／スタノール強化高ポリフェノール・ハーブティー
IT201700066508A1 (it) * 2017-06-15 2018-12-15 Isagro Spa Sospensioni concentrate di fitosteroli e relativo processo di preparazione

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US3800038A (en) * 1972-04-21 1974-03-26 Biolog Concepts Inc Uterine administraton of eutectic solid solutions of steroid hormones in a steroidal lipid carrier

Also Published As

Publication number Publication date
DK427674A (es) 1975-04-21
ZA744587B (en) 1976-02-25
DE2437845A1 (de) 1975-02-27
JPS5048115A (es) 1975-04-30
IL45311A0 (en) 1974-10-22
DD112899A5 (es) 1975-05-12
ATA655474A (de) 1977-02-15
US3881005A (en) 1975-04-29
AU7155674A (en) 1976-01-29
FR2240717B1 (es) 1977-11-04
NL7410862A (nl) 1975-02-17
FR2240717A1 (es) 1975-03-14
SE7410331L (es) 1975-02-14
BE818729A (fr) 1975-02-12

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