BE800373A - Dihydrate de l'acide 7-(d-alpha-amino-1,4- cyclohexadien-1- ylacetamido)desacetoxycephalosporanique - Google Patents

Dihydrate de l'acide 7-(d-alpha-amino-1,4- cyclohexadien-1- ylacetamido)desacetoxycephalosporanique

Info

Publication number
BE800373A
BE800373A BE131807A BE131807A BE800373A BE 800373 A BE800373 A BE 800373A BE 131807 A BE131807 A BE 131807A BE 131807 A BE131807 A BE 131807A BE 800373 A BE800373 A BE 800373A
Authority
BE
Belgium
Prior art keywords
ylacetamido
desacetoxycephalosporanic
cyclohexadien
alpha
amino
Prior art date
Application number
BE131807A
Other languages
English (en)
Inventor
F Dursch
T M Siewarga
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of BE800373A publication Critical patent/BE800373A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
BE131807A 1972-06-01 1973-06-01 Dihydrate de l'acide 7-(d-alpha-amino-1,4- cyclohexadien-1- ylacetamido)desacetoxycephalosporanique BE800373A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00258767A US3819620A (en) 1972-06-01 1972-06-01 7-(d-alpha-amino-1,4-cyclohexadien-1-ylacet-amido)desacetoxycephalosporanic acid dihydrate

Publications (1)

Publication Number Publication Date
BE800373A true BE800373A (fr) 1973-12-03

Family

ID=22982041

Family Applications (1)

Application Number Title Priority Date Filing Date
BE131807A BE800373A (fr) 1972-06-01 1973-06-01 Dihydrate de l'acide 7-(d-alpha-amino-1,4- cyclohexadien-1- ylacetamido)desacetoxycephalosporanique

Country Status (30)

Country Link
US (1) US3819620A (fr)
JP (1) JPS5544754B2 (fr)
KR (1) KR820001606B1 (fr)
AR (1) AR196669A1 (fr)
AT (1) AT322740B (fr)
AU (1) AU475833B2 (fr)
BE (1) BE800373A (fr)
BR (1) BR7303959D0 (fr)
CA (1) CA1004220A (fr)
CH (1) CH582185A5 (fr)
CS (1) CS178428B2 (fr)
DD (1) DD106181A5 (fr)
DE (1) DE2326880C2 (fr)
EG (1) EG11139A (fr)
ES (1) ES415420A1 (fr)
FI (1) FI57952C (fr)
FR (1) FR2186234B1 (fr)
GB (1) GB1426266A (fr)
HU (1) HU167052B (fr)
IE (1) IE38750B1 (fr)
IL (1) IL42243A (fr)
IN (1) IN138787B (fr)
IT (1) IT1068202B (fr)
NL (1) NL176267C (fr)
NO (1) NO144849C (fr)
PL (1) PL87262B1 (fr)
RO (2) RO68286A (fr)
SE (1) SE409714B (fr)
SU (1) SU465793A3 (fr)
ZA (1) ZA732889B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5725557B2 (fr) * 1972-11-17 1982-05-29
CH619233A5 (fr) * 1975-07-31 1980-09-15 Ciba Geigy Ag
US4054738A (en) * 1975-12-22 1977-10-18 Eli Lilly And Company Sodium cefamandole crystalline forms
US4946838A (en) * 1981-07-13 1990-08-07 E. R. Squibb & Sons, Inc. Crystalline anhydrous aztreonam
NZ220764A (en) * 1986-07-02 1989-09-27 Shionogi & Co Crystalline form of 7beta((z)-2-(2-aminothiazol-4-yl)-4- carboxybut-2-enoylamino)-3-cephem-4-carboxylic acid and pharmaceutical compositions
US4977257A (en) * 1988-11-14 1990-12-11 Eli Lilly And Company DMF solvates of a β-lactam antibiotic
WO1991000865A1 (fr) * 1989-07-10 1991-01-24 Gema S.A. Nouvelle forme de cephradine stable, procede de production de celle-ci, et produits intermediaires utilises
US5278157A (en) * 1989-07-10 1994-01-11 Gema, S.A. Stable cephradine hydrate
IT1289955B1 (it) * 1997-02-21 1998-10-19 Solchem Italiana Spa Acyclovir sale sodico biidrato e sua preparazione
CN1326860C (zh) * 2002-08-06 2007-07-18 北京化工大学 头孢拉定晶体以及制备头孢拉定的方法
SI1641933T1 (en) * 2003-07-03 2018-04-30 Dsm Sinochem Pharmaceuticals Netherlands B.V. A process for the preparation of cefradine
CN104688713A (zh) * 2015-03-20 2015-06-10 江苏亚邦强生药业有限公司 一种头孢拉定胶囊剂及其制备方法
CN112206217A (zh) * 2020-10-21 2021-01-12 迪沙药业集团有限公司 一种头孢拉定药物组合物及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3485819A (en) * 1968-07-02 1969-12-23 Squibb & Sons Inc Alpha-amino-cyclohexadienylalkylene-penicillins and cephalosporins

Also Published As

Publication number Publication date
IN138787B (fr) 1976-03-27
NL176267C (nl) 1985-03-18
FR2186234A1 (fr) 1974-01-11
CH582185A5 (fr) 1976-11-30
FR2186234B1 (fr) 1976-10-22
US3819620A (en) 1974-06-25
GB1426266A (en) 1976-02-25
PL87262B1 (fr) 1976-06-30
JPS4941520A (fr) 1974-04-18
DE2326880C2 (de) 1982-04-15
IT1068202B (it) 1985-03-21
DE2326880A1 (de) 1973-12-20
FI57952B (fi) 1980-07-31
AT322740B (de) 1975-06-10
DD106181A5 (fr) 1974-06-05
IL42243A0 (en) 1973-07-30
BR7303959D0 (pt) 1974-08-29
SE409714B (sv) 1979-09-03
CA1004220A (en) 1977-01-25
JPS5544754B2 (fr) 1980-11-13
AU5507473A (en) 1974-11-07
SU465793A3 (ru) 1975-03-30
NL7307321A (fr) 1973-12-04
KR820001606B1 (ko) 1982-09-08
IE38750B1 (en) 1978-05-24
NO144849C (no) 1981-11-25
EG11139A (en) 1978-03-29
HU167052B (fr) 1975-07-28
ZA732889B (en) 1974-04-24
AU475833B2 (en) 1976-09-02
NO144849B (no) 1981-08-17
RO63443A (fr) 1978-07-15
FI57952C (fi) 1981-09-07
CS178428B2 (fr) 1977-09-15
AR196669A1 (es) 1974-02-12
IL42243A (en) 1975-10-15
IE38750L (en) 1973-12-01
RO68286A (fr) 1980-12-30
ES415420A1 (es) 1976-02-16

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: E.R. SQUIBB & SONS INC.

Effective date: 19930601