BE762135A - Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer - Google Patents
Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquerInfo
- Publication number
- BE762135A BE762135A BE762135A BE762135A BE762135A BE 762135 A BE762135 A BE 762135A BE 762135 A BE762135 A BE 762135A BE 762135 A BE762135 A BE 762135A BE 762135 A BE762135 A BE 762135A
- Authority
- BE
- Belgium
- Prior art keywords
- thieno
- pyrimidines
- morpholino
- news
- manufacturing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19702003714 DE2003714C (de) | 1970-01-28 | 2 Piperazino 4 morpholino thieno eckige Klammer auf 3,2 d eckige Klammer zu pyrimidin und dessen Saureadditions salze | |
DE19702058086 DE2058086A1 (de) | 1970-11-26 | 1970-11-26 | Neue 4-Morpholino-thieno[3,2-d]pyrimidine,deren Salze und Verfahren zur Herstellung |
DE19702058085 DE2058085A1 (de) | 1970-11-26 | 1970-11-26 | Neues Verfahren zur Herstellung von 4-Morpholino-thieno[3,2-d]pyrimidinen |
Publications (1)
Publication Number | Publication Date |
---|---|
BE762135A true BE762135A (fr) | 1971-07-27 |
Family
ID=27182372
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE762135A BE762135A (fr) | 1970-01-28 | 1971-01-27 | Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer |
Country Status (9)
Country | Link |
---|---|
US (1) | US3763156A (pm) |
AU (1) | AU2468871A (pm) |
BE (1) | BE762135A (pm) |
ES (2) | ES387554A1 (pm) |
FR (1) | FR2081464B1 (pm) |
GB (1) | GB1309182A (pm) |
IL (1) | IL36079A0 (pm) |
NL (1) | NL7101043A (pm) |
NO (1) | NO129205B (pm) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1570494A (en) * | 1975-11-28 | 1980-07-02 | Ici Ltd | Thienopyrimidine derivatives and their use as pesticides |
US5280026A (en) * | 1989-05-30 | 1994-01-18 | Smithkline Beecham Intercredit B.V. | Thienopyrimidines |
GB8912335D0 (en) * | 1989-05-30 | 1989-07-12 | Smithkline Beckman Intercredit | Compounds |
US5098902A (en) * | 1991-03-18 | 1992-03-24 | Warner-Lambert Company | Method of treating neurodegenerative diseases |
US6187777B1 (en) | 1998-02-06 | 2001-02-13 | Amgen Inc. | Compounds and methods which modulate feeding behavior and related diseases |
US6608053B2 (en) * | 2000-04-27 | 2003-08-19 | Yamanouchi Pharmaceutical Co., Ltd. | Fused heteroaryl derivatives |
GB0423653D0 (en) * | 2004-10-25 | 2004-11-24 | Piramed Ltd | Pharmaceutical compounds |
EP2060575A1 (de) * | 2006-04-19 | 2009-05-20 | Boehringer Ingelheim International GmbH | Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen |
EP1847543A1 (de) | 2006-04-19 | 2007-10-24 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen |
DK2024372T3 (da) | 2006-04-26 | 2010-09-20 | Hoffmann La Roche | Thieno[3,2-d]pyrimidin-derivat, der er egnet som P13K inhibitor |
JP5546240B2 (ja) | 2006-04-26 | 2014-07-09 | ジェネンテック, インコーポレイテッド | 医薬化合物 |
JP5291616B2 (ja) * | 2006-04-26 | 2013-09-18 | ジェネンテック, インコーポレイテッド | ホスホイノシチド3−キナーゼ抑制剤化合物およびその使用方法 |
CL2007003523A1 (es) * | 2006-12-07 | 2008-08-22 | Piramed Ltd Genentech Inc | Compuestos derivados de heterociclos sustituidos con morfolina, inhibidores de la actividad de pi3 quinasa; composicion farmaceutica que comprende a dichos compuestos; kit farmaceutico; y su uso en el tratamiento profilactico o terapeutico del cancer |
AR064155A1 (es) * | 2006-12-07 | 2009-03-18 | Piramed Ltd | Compuestos de inhibidores de fosfoinositido-3 quinasa y metodos de uso |
WO2009042607A1 (en) | 2007-09-24 | 2009-04-02 | Genentech, Inc. | Thiazolopyrimidine p13k inhibitor compounds and methods of use |
EP2215093B1 (de) | 2007-10-19 | 2011-12-14 | Boehringer Ingelheim International GmbH | Neue piperazino-dihydrothienopyrimidin-derivate |
MY153979A (en) * | 2007-10-19 | 2015-04-30 | Boehringer Ingelheim Int | Substituted piperidino-dihydrothienopyrimidine |
US8637519B2 (en) * | 2007-10-19 | 2014-01-28 | Boehringer Ingelheim International Gmbh | Heterocycle-substituted piperazino-dihydrothienopyrimidines |
JP5348725B2 (ja) * | 2007-10-25 | 2013-11-20 | ジェネンテック, インコーポレイテッド | チエノピリミジン化合物の製造方法 |
GB0721095D0 (en) * | 2007-10-26 | 2007-12-05 | Piramed Ltd | Pharmaceutical compounds |
EP2405916B1 (en) | 2009-03-12 | 2018-02-07 | Genentech, Inc. | Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies |
BRPI1009022A2 (pt) | 2009-05-27 | 2016-03-08 | Hoffmann La Roche | "composto, composição farmacêutica, processo para produzir uma composição farmacêutica, uso de um composto, método para tratamento de uma doença ou transtorno e kit" |
EP2451811A1 (en) * | 2009-05-27 | 2012-05-16 | F. Hoffmann-La Roche AG | Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use |
NZ599939A (en) * | 2009-10-12 | 2014-02-28 | Hoffmann La Roche | Combinations of a pi3k inhibitor and a mek inhibitor |
BR112012026470A2 (pt) | 2010-04-16 | 2016-08-09 | Genentech Inc | método para prever a sensibilidade de crescimento de células tumorais e para tratar um tumor em um paciente |
WO2012088254A1 (en) | 2010-12-22 | 2012-06-28 | Genentech, Inc. | Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms |
US20130059866A1 (en) | 2011-08-24 | 2013-03-07 | Boehringer Ingelheim International Gmbh | Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma |
US9802954B2 (en) | 2011-08-24 | 2017-10-31 | Boehringer Ingelheim International Gmbh | Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma |
EP2959014B1 (en) | 2013-02-25 | 2019-11-13 | Genentech, Inc. | Methods and compositions for detecting and treating drug resistant akt mutant |
WO2020072504A1 (en) * | 2018-10-01 | 2020-04-09 | Genzyme Corporation | Thieno[3,2-b]pyridine derivatives as udp glycosyltransferase inhibitors and methods of use |
GB202014736D0 (en) * | 2020-09-18 | 2020-11-04 | Imperial College Innovations Ltd | Novel compounds and their use in therapy |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1470356A1 (de) * | 1964-01-15 | 1970-04-30 | Thomae Gmbh Dr K | Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung |
-
1971
- 1971-01-22 US US00108988A patent/US3763156A/en not_active Expired - Lifetime
- 1971-01-23 ES ES387554A patent/ES387554A1/es not_active Expired
- 1971-01-23 ES ES387553A patent/ES387553A1/es not_active Expired
- 1971-01-26 AU AU24688/71A patent/AU2468871A/en not_active Expired
- 1971-01-27 NO NO00283/71A patent/NO129205B/no unknown
- 1971-01-27 IL IL36079A patent/IL36079A0/xx unknown
- 1971-01-27 BE BE762135A patent/BE762135A/xx unknown
- 1971-01-27 NL NL7101043A patent/NL7101043A/xx unknown
- 1971-01-28 FR FR7102796A patent/FR2081464B1/fr not_active Expired
- 1971-04-19 GB GB2046471A patent/GB1309182A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
AU2468871A (en) | 1972-07-27 |
FR2081464A1 (pm) | 1971-12-03 |
GB1309182A (en) | 1973-03-07 |
ES387553A1 (es) | 1974-01-16 |
NL7101043A (pm) | 1971-07-30 |
US3763156A (en) | 1973-10-02 |
FR2081464B1 (pm) | 1975-04-18 |
ES387554A1 (es) | 1974-01-16 |
IL36079A0 (en) | 1971-03-24 |
NO129205B (pm) | 1974-03-11 |
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