BE762135A - Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer - Google Patents

Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer

Info

Publication number
BE762135A
BE762135A BE762135A BE762135A BE762135A BE 762135 A BE762135 A BE 762135A BE 762135 A BE762135 A BE 762135A BE 762135 A BE762135 A BE 762135A BE 762135 A BE762135 A BE 762135A
Authority
BE
Belgium
Prior art keywords
thieno
pyrimidines
morpholino
news
manufacturing
Prior art date
Application number
BE762135A
Other languages
English (en)
French (fr)
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19702003714 external-priority patent/DE2003714C/de
Priority claimed from DE19702058086 external-priority patent/DE2058086A1/de
Priority claimed from DE19702058085 external-priority patent/DE2058085A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of BE762135A publication Critical patent/BE762135A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BE762135A 1970-01-28 1971-01-27 Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer BE762135A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19702003714 DE2003714C (de) 1970-01-28 2 Piperazino 4 morpholino thieno eckige Klammer auf 3,2 d eckige Klammer zu pyrimidin und dessen Saureadditions salze
DE19702058086 DE2058086A1 (de) 1970-11-26 1970-11-26 Neue 4-Morpholino-thieno[3,2-d]pyrimidine,deren Salze und Verfahren zur Herstellung
DE19702058085 DE2058085A1 (de) 1970-11-26 1970-11-26 Neues Verfahren zur Herstellung von 4-Morpholino-thieno[3,2-d]pyrimidinen

Publications (1)

Publication Number Publication Date
BE762135A true BE762135A (fr) 1971-07-27

Family

ID=27182372

Family Applications (1)

Application Number Title Priority Date Filing Date
BE762135A BE762135A (fr) 1970-01-28 1971-01-27 Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer

Country Status (9)

Country Link
US (1) US3763156A (OSRAM)
AU (1) AU2468871A (OSRAM)
BE (1) BE762135A (OSRAM)
ES (2) ES387554A1 (OSRAM)
FR (1) FR2081464B1 (OSRAM)
GB (1) GB1309182A (OSRAM)
IL (1) IL36079A0 (OSRAM)
NL (1) NL7101043A (OSRAM)
NO (1) NO129205B (OSRAM)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1570494A (en) * 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
US5280026A (en) * 1989-05-30 1994-01-18 Smithkline Beecham Intercredit B.V. Thienopyrimidines
GB8912335D0 (en) * 1989-05-30 1989-07-12 Smithkline Beckman Intercredit Compounds
US5098902A (en) * 1991-03-18 1992-03-24 Warner-Lambert Company Method of treating neurodegenerative diseases
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
GB0423653D0 (en) 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
EP1847543A1 (de) 2006-04-19 2007-10-24 Boehringer Ingelheim Pharma GmbH & Co. KG Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
PT1874781E (pt) * 2006-04-19 2009-07-27 Boehringer Ingelheim Int Di-hidro-tienopirimidinas para o tratamento de doenças inflamatórias
KR101402474B1 (ko) * 2006-04-26 2014-06-19 제넨테크, 인크. 포스포이노시티드 3-키나제 억제제 화합물 및 이를 포함하는 약학적 조성물
KR101533461B1 (ko) 2006-04-26 2015-07-02 에프. 호프만-라 로슈 아게 Ｐｉ３ｋ저해제로 유용한 티에노［3,2-ｄ］피리미딘 유도체
CN101479274B (zh) * 2006-04-26 2013-06-12 霍夫曼-拉罗奇有限公司 药用化合物
KR101507182B1 (ko) * 2006-12-07 2015-03-30 제넨테크, 인크. 포스포이노시타이드 3-키나제 억제제 화합물 및 그의 사용 방법
AU2007329352B2 (en) * 2006-12-07 2013-01-17 F. Hoffmann-La Roche Ag Phosphoinositide 3-kinase inhibitor compounds and methods of use
ES2399774T3 (es) 2007-09-24 2013-04-03 Genentech, Inc. Compuestos de tiazolopirimidina inhibidores de PI3K y métodos de uso
CA2702518A1 (en) 2007-10-19 2009-04-23 Boehringer Ingelheim International Gmbh New piperazino-dihydrothienopyrimidine derivatives
KR20100075930A (ko) 2007-10-19 2010-07-05 베링거 인겔하임 인터내셔날 게엠베하 헤테로사이클-치환된 피페라지노-디하이드로티에노피리미딘
BRPI0818006B8 (pt) * 2007-10-19 2021-05-25 Boehringer Ingelheim Int compostos de piperidino-di-hidrotienopirimidinas substituídas, uso dos mesmos e formulações farmacêuticas
CA2701292C (en) 2007-10-25 2015-03-24 Genentech, Inc. Process for making thienopyrimidine compounds
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
JP5709766B2 (ja) 2009-03-12 2015-04-30 ジェネンテック， インコーポレイテッド 造血器腫瘍の治療のためのホスホイノシチド３キナーゼ阻害剤化合物と化学療法剤の併用
CA2772371A1 (en) * 2009-05-27 2010-12-02 F. Hoffmann-La Roche Ag Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
WO2010138589A1 (en) * 2009-05-27 2010-12-02 Genentech, Inc. Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
MX345155B (es) * 2009-10-12 2017-01-18 F Hoffmann-La Roche Ag * Combinaciones de un inhibidor de pi3k y un inhibidor de mek.
CN103038643A (zh) 2010-04-16 2013-04-10 基因泰克公司 作为pi3k/akt激酶途径抑制剂效能的预测性生物标记的foxo3a
WO2012088254A1 (en) 2010-12-22 2012-06-28 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
US20130059866A1 (en) 2011-08-24 2013-03-07 Boehringer Ingelheim International Gmbh Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
US9802954B2 (en) 2011-08-24 2017-10-31 Boehringer Ingelheim International Gmbh Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
MX369175B (es) 2013-02-25 2019-10-30 Genentech Inc Métodos para detectar mutantes de akt resistentes a fármacos.
AU2019355870B2 (en) * 2018-10-01 2023-11-16 Genzyme Corporation Thieno[3,2-b]pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use
GB202014736D0 (en) * 2020-09-18 2020-11-04 Imperial College Innovations Ltd Novel compounds and their use in therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1470356A1 (de) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
AU2468871A (en) 1972-07-27
NL7101043A (OSRAM) 1971-07-30
ES387554A1 (es) 1974-01-16
IL36079A0 (en) 1971-03-24
GB1309182A (en) 1973-03-07
US3763156A (en) 1973-10-02
ES387553A1 (es) 1974-01-16
FR2081464B1 (OSRAM) 1975-04-18
FR2081464A1 (OSRAM) 1971-12-03
NO129205B (OSRAM) 1974-03-11

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