BE1024420B1 - Polynucleotides et polypeptides d'adenovirus - Google Patents

Polynucleotides et polypeptides d'adenovirus Download PDF

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Publication number
BE1024420B1
BE1024420B1 BE2016/5434A BE201605434A BE1024420B1 BE 1024420 B1 BE1024420 B1 BE 1024420B1 BE 2016/5434 A BE2016/5434 A BE 2016/5434A BE 201605434 A BE201605434 A BE 201605434A BE 1024420 B1 BE1024420 B1 BE 1024420B1
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BE
Belgium
Prior art keywords
amino acid
acid sequence
seq
polypeptide
polynucleotide
Prior art date
Application number
BE2016/5434A
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English (en)
French (fr)
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BE1024420A1 (fr
Inventor
Stefano Colloca
Virginia Ammendola
Fabiana Grazioli
Alessandra Vitelli
Alfredo Nicosia
Riccardo Cortese
Original Assignee
Glaxosmithkline Biologicals Sa
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Priority claimed from PCT/EP2015/063248 external-priority patent/WO2015189425A1/en
Priority claimed from GBGB1510357.5A external-priority patent/GB201510357D0/en
Priority claimed from GBGB1514772.1A external-priority patent/GB201514772D0/en
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of BE1024420A1 publication Critical patent/BE1024420A1/fr
Application granted granted Critical
Publication of BE1024420B1 publication Critical patent/BE1024420B1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01—DNA viruses
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N2710/10011—Adenoviridae
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    • C12N2710/10011—Adenoviridae
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BE2016/5434A 2015-06-12 2016-06-10 Polynucleotides et polypeptides d'adenovirus BE1024420B1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP1510357.5 2015-06-12
PCT/EP2015/063248 WO2015189425A1 (en) 2014-06-13 2015-06-12 Immunogenic combinations
GBGB1510357.5A GB201510357D0 (en) 2015-06-12 2015-06-12 Adenovirus polynucleotides and polypeptides
GB1510357.5 2015-06-12
GBGB1514772.1A GB201514772D0 (en) 2015-08-19 2015-08-19 Adenovirus polynucleotides and polypeptides

Publications (2)

Publication Number Publication Date
BE1024420A1 BE1024420A1 (fr) 2018-02-12
BE1024420B1 true BE1024420B1 (fr) 2018-02-19

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BE2016/5434A BE1024420B1 (fr) 2015-06-12 2016-06-10 Polynucleotides et polypeptides d'adenovirus

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US (4) US11254711B2 (enExample)
EP (2) EP3307313A1 (enExample)
JP (2) JP6983665B2 (enExample)
KR (2) KR102535670B1 (enExample)
CN (2) CN108025058B (enExample)
AU (4) AU2016275619B2 (enExample)
BE (1) BE1024420B1 (enExample)
BR (1) BR112017026523A2 (enExample)
CA (2) CA2988654A1 (enExample)
EA (1) EA038402B9 (enExample)
IL (2) IL256069B2 (enExample)
MX (2) MX2017016101A (enExample)
WO (2) WO2016198621A1 (enExample)

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GB201513176D0 (en) 2015-07-27 2015-09-09 Glaxosmithkline Biolog Sa Novel methods for inducing an immune response
ES2959811T3 (es) * 2016-12-09 2024-02-28 Glaxosmithkline Biologicals Sa Construcciones de adenovirus de chimpancé con antígenos de Lyssavirus
GB201620968D0 (en) 2016-12-09 2017-01-25 Glaxosmithkline Biologicals Sa Adenovirus polynucleotides and polypeptides
WO2019016756A1 (en) 2017-07-21 2019-01-24 Glaxosmithkline Biologicals Sa ANTIGEN CONSTRUCTS OF CHIKUNGUNYA VIRUSES
WO2019076892A1 (en) 2017-10-16 2019-04-25 Glaxosmithkline Biologicals Sa ENHANCED PROMOTER
CN111479926A (zh) 2017-10-16 2020-07-31 葛兰素史密丝克莱恩生物有限公司 具有两个表达盒的猿猴腺病毒载体
SG11202003058UA (en) 2017-10-16 2020-04-29 Glaxosmithkline Biologicals Sa Replication competent adenoviral vectors
US11859199B2 (en) 2017-10-16 2024-01-02 Glaxosmithkline Biologicals Sa Adenoviral vectors with two expression cassettes encoding RSV antigenic proteins or fragments thereof
MX2020004487A (es) * 2017-10-31 2020-08-13 Janssen Vaccines & Prevention Bv Adenovirus y usos de estos.
GB201721068D0 (en) 2017-12-15 2018-01-31 Glaxosmithkline Biologicals Sa Hepatitis B immunisation regimen and compositions
GB201721069D0 (en) 2017-12-15 2018-01-31 Glaxosmithkline Biologicals Sa Hepatitis B Immunisation regimen and compositions
BR112020012361A2 (pt) 2017-12-20 2020-11-24 Glaxosmithkline Biologicals S.A. constructos de antígeno do vírus epstein-barr
CN112638936A (zh) * 2018-06-12 2021-04-09 葛兰素史密丝克莱恩生物有限公司 腺病毒多核苷酸和多肽
US20210277417A1 (en) * 2018-06-25 2021-09-09 Akouos, Inc. Methods of treating clrn1-associated hearing loss and/or vision loss
EP3587581A1 (en) 2018-06-26 2020-01-01 GlaxoSmithKline Biologicals S.A. Formulations for simian adenoviral vectors having enhanced storage stability
EP3810277A1 (en) * 2018-07-20 2021-04-28 Janssen Vaccines & Prevention B.V. Recombinant adenoviral vector expressing zika antigen with improved productivity
US20210283238A1 (en) 2018-08-07 2021-09-16 Glaxosmithkline Biologicals Sa Novel processes and vaccines
EP3897846A1 (en) 2018-12-21 2021-10-27 GlaxoSmithKline Biologicals SA Methods of inducing an immune response
US20220339281A1 (en) 2019-03-05 2022-10-27 GalxoSmithKline Biologicals SA Hepatitis b immunisation regimen and compositions
US20230109362A1 (en) 2020-05-14 2023-04-06 Glaxosmithkline Biologicals Sa Viral biosensors
WO2025038011A1 (en) * 2023-08-11 2025-02-20 Joint Stock Company «Biocad» Modified sequence of adenovirus e2a gene for producing vectors based on adeno-associated viruses (aav) (variants)

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