AU777328B2 - Method of promoting bone growth with hyaluronic acid and growth factors - Google Patents

Method of promoting bone growth with hyaluronic acid and growth factors Download PDF

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Publication number
AU777328B2
AU777328B2 AU63797/00A AU6379700A AU777328B2 AU 777328 B2 AU777328 B2 AU 777328B2 AU 63797/00 A AU63797/00 A AU 63797/00A AU 6379700 A AU6379700 A AU 6379700A AU 777328 B2 AU777328 B2 AU 777328B2
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AU
Australia
Prior art keywords
bone
bfgf
composition
hyaluronic acid
site
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU63797/00A
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English (en)
Other versions
AU6379700A (en
Inventor
Michael Randomsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DePuy Spine LLC
Original Assignee
DePuy Acromed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DePuy Acromed Inc filed Critical DePuy Acromed Inc
Publication of AU6379700A publication Critical patent/AU6379700A/en
Assigned to DEPUY ACROMED, INC. reassignment DEPUY ACROMED, INC. Alteration of Name(s) of Applicant(s) under S113 Assignors: ORQUEST, INC.
Application granted granted Critical
Publication of AU777328B2 publication Critical patent/AU777328B2/en
Priority to AU2005200146A priority Critical patent/AU2005200146B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1825Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU63797/00A 1999-07-26 2000-07-26 Method of promoting bone growth with hyaluronic acid and growth factors Ceased AU777328B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2005200146A AU2005200146B2 (en) 1999-07-26 2005-01-13 Method of promoting bone growth with hyaluronic acid and growth factors

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/360543 1999-07-26
US09/360,543 US6221854B1 (en) 1996-03-05 1999-07-26 Method of promoting bone growth with hyaluronic acid and growth factors
PCT/US2000/020373 WO2001007056A1 (en) 1999-07-26 2000-07-26 Method of promoting bone growth with hyaluronic acid and growth factors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2005200146A Division AU2005200146B2 (en) 1999-07-26 2005-01-13 Method of promoting bone growth with hyaluronic acid and growth factors

Publications (2)

Publication Number Publication Date
AU6379700A AU6379700A (en) 2001-02-13
AU777328B2 true AU777328B2 (en) 2004-10-14

Family

ID=23418431

Family Applications (1)

Application Number Title Priority Date Filing Date
AU63797/00A Ceased AU777328B2 (en) 1999-07-26 2000-07-26 Method of promoting bone growth with hyaluronic acid and growth factors

Country Status (7)

Country Link
US (3) US6221854B1 (enExample)
EP (1) EP1198235A4 (enExample)
JP (2) JP2003505422A (enExample)
AU (1) AU777328B2 (enExample)
CA (1) CA2378328A1 (enExample)
NZ (1) NZ516097A (enExample)
WO (1) WO2001007056A1 (enExample)

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US20050043234A1 (en) * 1996-10-16 2005-02-24 Deisher Theresa A. Novel FGF homologs
US6907679B2 (en) * 1998-11-12 2005-06-21 Qlt Usa, Inc. Method for lyophilizing an active agent
US6722054B2 (en) 1998-11-12 2004-04-20 Atrix Laboratories, Inc. Process and delivery container for lyophilizing active agent
US6566144B1 (en) * 2000-03-27 2003-05-20 Atrix Laboratories Cover plate for use in lyophilization
WO2002085422A1 (en) * 2001-04-25 2002-10-31 Eidgenössische Technische Hochschule Zürich Drug delivery matrices to enhance wound healing
US7008626B2 (en) * 2001-11-05 2006-03-07 Seikagaku Corporation Medical composition for protuberance of epithelium
US7247609B2 (en) * 2001-12-18 2007-07-24 Universitat Zurich Growth factor modified protein matrices for tissue engineering
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EP1525011B1 (en) * 2002-07-31 2016-08-17 DENTSPLY International Inc. Bone repair putty comprising porous particulate and carrier gel
US8876532B2 (en) 2002-07-31 2014-11-04 Dentsply International Inc. Bone repair putty
CA2500742C (en) * 2002-10-07 2014-02-18 Zymogenetics, Inc. Compositions of fgf-18 and hyaluronic acid for stimulating cartilage production and treating osteoarthritis
WO2004062588A2 (en) * 2003-01-06 2004-07-29 University Of Utah Water-soluble polymeric bone-targeting drug delivery system
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
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WO2006014444A1 (en) 2004-07-06 2006-02-09 Zymogenetics, Inc. Pharmaceutical composition comprising fgf18 and il-1 antagonist and method of use
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
EP1828244A2 (en) * 2004-12-22 2007-09-05 Kuros Biosurgery AG Michael-type addition reaction functionalised peg hydrogels with factor xiiia incorporated biofactors
WO2006073711A2 (en) * 2005-01-06 2006-07-13 Kuros Biosurgery Ag Use of a matrix comprising a contrast agent in soft tissues
US8575101B2 (en) 2005-01-06 2013-11-05 Kuros Biosurgery Ag Supplemented matrices for the repair of bone fractures
JP5328153B2 (ja) * 2005-01-06 2013-10-30 バクスター・インターナショナル・インコーポレーテッド 骨折修復のための強化(supplemented)マトリックス
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
RU2472809C2 (ru) * 2005-09-02 2013-01-20 Колбар Лайфсайенс Лтд. Поперечно сшитые полисахаридные и белковые матрицы и способы их получения
WO2007035778A2 (en) 2005-09-19 2007-03-29 Histogenics Corporation Cell-support matrix and a method for preparation thereof
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US20080255041A1 (en) * 2007-04-11 2008-10-16 Ebi, L.P. Treatment of annulus fibrosis defects
US8685107B2 (en) 2007-07-03 2014-04-01 Histogenics Corporation Double-structured tissue implant and a method for preparation and use thereof
US20090054984A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects
WO2009012367A1 (en) * 2007-07-18 2009-01-22 Aesthetic Science Composition and method of use for soft tissue augmentation/drug delivery
CA2705850C (en) 2007-11-13 2016-07-19 Bio-Technology General (Israel) Ltd. Dilute filtration sterilization process for viscoelastic biopolymers
CA2717725A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
EP2686027B1 (en) 2011-03-16 2021-05-05 Kuros Biosurgery AG Pharmaceutical formulation for use in spinal fusion
WO2012140650A2 (en) 2011-04-12 2012-10-18 Hepacore Ltd. Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
GEP20217312B (en) 2016-02-05 2021-11-10 Tolmar International Ltd Vented cover plate for an array of syringes
US11834680B2 (en) 2017-06-28 2023-12-05 Rutgers, The State University Of New Jersey Single kidney cell-derived organoids
EP3644965A4 (en) * 2017-06-28 2021-05-05 Rutgers, The State University of New Jersey ORGANOIDS DERIVED FROM A SINGLE BRAIN CELL
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Citations (1)

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Also Published As

Publication number Publication date
JP2009143949A (ja) 2009-07-02
US20010014664A1 (en) 2001-08-16
AU6379700A (en) 2001-02-13
WO2001007056A1 (en) 2001-02-01
EP1198235A1 (en) 2002-04-24
CA2378328A1 (en) 2001-02-01
WO2001007056A9 (en) 2002-07-25
US6221854B1 (en) 2001-04-24
US7902172B2 (en) 2011-03-08
US6703377B2 (en) 2004-03-09
JP2003505422A (ja) 2003-02-12
EP1198235A4 (en) 2006-04-05
US20040176295A1 (en) 2004-09-09
NZ516097A (en) 2004-02-27

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Owner name: DEPUY ACROMED, INC.

Free format text: THE FORMER OWNER WAS: ORQUEST, INC.