JP2003505422A - ヒアルロン酸と成長因子を用いた骨成長促進方法 - Google Patents
ヒアルロン酸と成長因子を用いた骨成長促進方法Info
- Publication number
- JP2003505422A JP2003505422A JP2001511940A JP2001511940A JP2003505422A JP 2003505422 A JP2003505422 A JP 2003505422A JP 2001511940 A JP2001511940 A JP 2001511940A JP 2001511940 A JP2001511940 A JP 2001511940A JP 2003505422 A JP2003505422 A JP 2003505422A
- Authority
- JP
- Japan
- Prior art keywords
- bone
- bfgf
- composition
- growth
- hyaluronic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
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- Animal Behavior & Ethology (AREA)
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- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| PCT/US2000/020373 WO2001007056A1 (en) | 1999-07-26 | 2000-07-26 | Method of promoting bone growth with hyaluronic acid and growth factors |
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| US6221854B1 (en) * | 1996-03-05 | 2001-04-24 | Orquest, Inc. | Method of promoting bone growth with hyaluronic acid and growth factors |
| US6645945B1 (en) | 1996-03-05 | 2003-11-11 | Depuy Acromed, Inc. | Method of treating diseased, injured or abnormal cartilage with hyaluronic acid and growth factors |
| US5942499A (en) * | 1996-03-05 | 1999-08-24 | Orquest, Inc. | Method of promoting bone growth with hyaluronic acid and growth factors |
| CA2246747C (en) | 1996-03-05 | 2011-01-04 | Orquest, Inc. | Method of promoting bone growth with hyaluronic acid and growth factors |
| JP2002504083A (ja) * | 1996-03-05 | 2002-02-05 | オーケスト インコーポレイテッド | ヒアルロン酸および増殖因子による骨の増殖を促進する方法 |
| KR100236771B1 (ko) * | 1997-04-01 | 2000-02-01 | 성재갑 | 히아루론산을 이용한 약물의 서방성 미세입자 제형 |
| IT1288290B1 (it) * | 1996-06-21 | 1998-09-11 | Fidia Spa In Amministrazione S | Acido ialuronico autoreticolato e relative composizioni farmaceutiche per il trattamento delle artropatie |
| CA2267111A1 (en) * | 1996-09-30 | 1998-04-09 | Children's Medical Center Corporation | Methods and compositions for programming an organic matrix for remodeling into a target tissue |
| US6281195B1 (en) | 1997-02-07 | 2001-08-28 | Stryker Corporation | Matrix-free osteogenic devices, implants and methods of use thereof |
| CN1161127C (zh) * | 1997-07-03 | 2004-08-11 | 奥奎斯特公司 | 交联的多糖药物载体 |
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1999
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2000
- 2000-07-26 NZ NZ516097A patent/NZ516097A/xx not_active IP Right Cessation
- 2000-07-26 AU AU63797/00A patent/AU777328B2/en not_active Ceased
- 2000-07-26 CA CA002378328A patent/CA2378328A1/en not_active Abandoned
- 2000-07-26 JP JP2001511940A patent/JP2003505422A/ja active Pending
- 2000-07-26 WO PCT/US2000/020373 patent/WO2001007056A1/en not_active Ceased
- 2000-07-26 EP EP00950736A patent/EP1198235A4/en not_active Ceased
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2004
- 2004-03-08 US US10/796,441 patent/US7902172B2/en not_active Expired - Fee Related
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2009
- 2009-02-12 JP JP2009030095A patent/JP2009143949A/ja active Pending
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|---|---|
| JP2009143949A (ja) | 2009-07-02 |
| US20010014664A1 (en) | 2001-08-16 |
| AU6379700A (en) | 2001-02-13 |
| WO2001007056A1 (en) | 2001-02-01 |
| EP1198235A1 (en) | 2002-04-24 |
| CA2378328A1 (en) | 2001-02-01 |
| WO2001007056A9 (en) | 2002-07-25 |
| US6221854B1 (en) | 2001-04-24 |
| US7902172B2 (en) | 2011-03-08 |
| US6703377B2 (en) | 2004-03-09 |
| EP1198235A4 (en) | 2006-04-05 |
| US20040176295A1 (en) | 2004-09-09 |
| AU777328B2 (en) | 2004-10-14 |
| NZ516097A (en) | 2004-02-27 |
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