AU777005B2 - Protein A based binding domains with desirable activities - Google Patents

Protein A based binding domains with desirable activities Download PDF

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Publication number
AU777005B2
AU777005B2 AU50191/00A AU5019100A AU777005B2 AU 777005 B2 AU777005 B2 AU 777005B2 AU 50191/00 A AU50191/00 A AU 50191/00A AU 5019100 A AU5019100 A AU 5019100A AU 777005 B2 AU777005 B2 AU 777005B2
Authority
AU
Australia
Prior art keywords
spa
variant
fab
domain
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU50191/00A
Other languages
English (en)
Other versions
AU5019100A (en
Inventor
Gregg J. Silverman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California San Diego UCSD filed Critical University of California San Diego UCSD
Publication of AU5019100A publication Critical patent/AU5019100A/en
Application granted granted Critical
Publication of AU777005B2 publication Critical patent/AU777005B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU50191/00A 1999-05-15 2000-05-15 Protein A based binding domains with desirable activities Ceased AU777005B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13438699P 1999-05-15 1999-05-15
US60/134386 1999-05-15
PCT/US2000/013402 WO2000069457A1 (en) 1999-05-15 2000-05-15 Protein a based binding domains with desirable activities

Publications (2)

Publication Number Publication Date
AU5019100A AU5019100A (en) 2000-12-05
AU777005B2 true AU777005B2 (en) 2004-09-30

Family

ID=22463140

Family Applications (1)

Application Number Title Priority Date Filing Date
AU50191/00A Ceased AU777005B2 (en) 1999-05-15 2000-05-15 Protein A based binding domains with desirable activities

Country Status (6)

Country Link
US (1) US20060205016A1 (https=)
EP (2) EP1181052A4 (https=)
JP (1) JP2002544237A (https=)
AU (1) AU777005B2 (https=)
CA (1) CA2374013A1 (https=)
WO (1) WO2000069457A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7425331B2 (en) 2002-04-10 2008-09-16 Protalex, Inc. Protein A methods of use
US7211258B2 (en) 2002-04-10 2007-05-01 Protalex, Inc. Protein A compositions and methods of use
EP2066419B1 (en) 2006-09-29 2015-11-11 GE Healthcare Bio-Sciences AB Chromatography ligand comprising domain c from staphyloccocus aureus protein a for antibody isolation
WO2008067547A2 (en) * 2006-11-30 2008-06-05 Research Development Foundation Improved immunoglobulin libraries
EP2099932A4 (en) 2006-12-06 2009-11-18 Repligen Corp NUCLEIC ACIDS ENCODING THE RECOMBINANT PROTEIN A
US8592555B2 (en) * 2008-08-11 2013-11-26 Emd Millipore Corporation Immunoglobulin-binding proteins with improved specificity
CN102165312B (zh) * 2008-09-25 2015-04-22 Jsr株式会社 亲合层析用填充剂
SG195555A1 (en) * 2008-12-24 2013-12-30 Emd Millipore Corp Caustic stable chromatography ligands
WO2010110288A1 (ja) * 2009-03-24 2010-09-30 株式会社カネカ 免疫グロブリンに親和性を有するタンパク質および免疫グロブリン結合性アフィニティーリガンド
ES2784957T3 (es) * 2009-04-03 2020-10-02 Univ Chicago Composiciones y métodos relacionados con variantes de la proteína A (SPA)
JP6002128B2 (ja) 2010-07-02 2016-10-05 ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago プロテインA(SpA)変種に関連する組成物および方法
SG186552A1 (en) 2011-06-08 2013-01-30 Emd Millipore Corp Chromatography matrices including novel staphylococcus aureus protein a based ligands
BR112014003315A2 (pt) * 2011-08-15 2017-03-01 Univ Chicago composições e métodos relacionados a anticorpos para a proteína a estafilocócica
US20160074497A1 (en) * 2013-05-03 2016-03-17 The University Of Chicago Staphylococcus live cell vaccines
GB201506868D0 (en) * 2015-04-22 2015-06-03 Ucb Biopharma Sprl Method for protein purification
MX2021013833A (es) 2019-05-14 2022-03-17 Univ Chicago Metodos y composiciones que comprenden variantes de la proteina a de estafilococos (spa).
WO2021051136A1 (en) 2019-09-13 2021-03-18 The University Of Chicago Methods and compositions for treating staphylococcal infections
WO2025036605A1 (en) * 2023-08-14 2025-02-20 Cytiva Bioprocess R&D Ab Vh3 binding separation matrix and methods for using the same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5831012A (en) * 1994-01-14 1998-11-03 Pharmacia & Upjohn Aktiebolag Bacterial receptor structures

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8300693L (sv) * 1983-02-09 1984-08-10 Sven Lofdahl Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US4879378A (en) 1989-03-30 1989-11-07 Union Carbide Chemicals And Plastics Company Inc. Polysiloxanes with pendant sterically hindered phenol moiety connected to the silicon atom via a carbonylyoxy-containing link
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5198531A (en) 1991-06-14 1993-03-30 Research Diagnostic Antibodies Polymeric resin for peptide synthesis
US5240680A (en) 1991-12-19 1993-08-31 Chiron Corporation Automated apparatus for use in peptide synthesis
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US5891438A (en) * 1992-10-30 1999-04-06 The Regents Of The University Of California Method for stimulating production of variable region gene family restricted antibodies through B-cell superantigen vaccination
CA2245835A1 (en) 1995-06-14 1997-01-03 The Regents Of The University Of California Novel high affinity human antibodies to tumor antigens
US6031071A (en) 1996-01-24 2000-02-29 Biophage, Inc. Methods of generating novel peptides
AU2429397A (en) * 1996-03-29 1997-10-22 David S. Terman Polymerized staphylococcal protein a for treatment of diseases
US6013763A (en) * 1996-06-04 2000-01-11 Genentech, Inc. Peptide variants of protein A

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5831012A (en) * 1994-01-14 1998-11-03 Pharmacia & Upjohn Aktiebolag Bacterial receptor structures

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
OLSZEWSKI K A ET AL. PROTEINS STRU. FUNC. & GEN. (1996) P286 *
ROBEN P W ET AL. JNL. OF IMMUN. (1995) VOL.154(12),PP6437-45 *

Also Published As

Publication number Publication date
EP1181052A1 (en) 2002-02-27
WO2000069457A1 (en) 2000-11-23
EP2017343A3 (en) 2009-01-28
US20060205016A1 (en) 2006-09-14
AU5019100A (en) 2000-12-05
JP2002544237A (ja) 2002-12-24
EP2017343A2 (en) 2009-01-21
CA2374013A1 (en) 2000-11-23
EP1181052A4 (en) 2004-08-11

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