AU777005B2 - Protein A based binding domains with desirable activities - Google Patents

Protein A based binding domains with desirable activities Download PDF

Info

Publication number
AU777005B2
AU777005B2 AU50191/00A AU5019100A AU777005B2 AU 777005 B2 AU777005 B2 AU 777005B2 AU 50191/00 A AU50191/00 A AU 50191/00A AU 5019100 A AU5019100 A AU 5019100A AU 777005 B2 AU777005 B2 AU 777005B2
Authority
AU
Australia
Prior art keywords
spa
variant
fab
domain
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU50191/00A
Other languages
English (en)
Other versions
AU5019100A (en
Inventor
Gregg J. Silverman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California San Diego UCSD filed Critical University of California San Diego UCSD
Publication of AU5019100A publication Critical patent/AU5019100A/en
Application granted granted Critical
Publication of AU777005B2 publication Critical patent/AU777005B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU50191/00A 1999-05-15 2000-05-15 Protein A based binding domains with desirable activities Ceased AU777005B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13438699P 1999-05-15 1999-05-15
US60/134386 1999-05-15
PCT/US2000/013402 WO2000069457A1 (en) 1999-05-15 2000-05-15 Protein a based binding domains with desirable activities

Publications (2)

Publication Number Publication Date
AU5019100A AU5019100A (en) 2000-12-05
AU777005B2 true AU777005B2 (en) 2004-09-30

Family

ID=22463140

Family Applications (1)

Application Number Title Priority Date Filing Date
AU50191/00A Ceased AU777005B2 (en) 1999-05-15 2000-05-15 Protein A based binding domains with desirable activities

Country Status (6)

Country Link
US (1) US20060205016A1 (enExample)
EP (2) EP1181052A4 (enExample)
JP (1) JP2002544237A (enExample)
AU (1) AU777005B2 (enExample)
CA (1) CA2374013A1 (enExample)
WO (1) WO2000069457A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7211258B2 (en) 2002-04-10 2007-05-01 Protalex, Inc. Protein A compositions and methods of use
US7425331B2 (en) 2002-04-10 2008-09-16 Protalex, Inc. Protein A methods of use
JP5345539B2 (ja) 2006-09-29 2013-11-20 ジーイー・ヘルスケア・バイオ−サイエンシズ・アーベー 抗体単離のためのスタフィロコッカスアウレウス由来のドメインcを含むクロマトグラフィーリガンド
ATE555128T1 (de) * 2006-11-30 2012-05-15 Res Dev Foundation Verbesserte immunglobulin-bibliotheken
WO2008127457A2 (en) 2006-12-06 2008-10-23 Repligen Corporation Nucleic acids encoding recombinant protein a
US8592555B2 (en) * 2008-08-11 2013-11-26 Emd Millipore Corporation Immunoglobulin-binding proteins with improved specificity
JP5626526B2 (ja) * 2008-09-25 2014-11-19 Jsr株式会社 アフィニティークロマトグラフィー用充填剤
SG162687A1 (en) 2008-12-24 2010-07-29 Millipore Corp Caustic stable chromatography ligands
WO2010110288A1 (ja) 2009-03-24 2010-09-30 株式会社カネカ 免疫グロブリンに親和性を有するタンパク質および免疫グロブリン結合性アフィニティーリガンド
SMT202000246T1 (it) * 2009-04-03 2020-07-08 Univ Chicago Composizioni e metodi relativi a varianti della proteina a (spa)
BR112013000097B1 (pt) * 2010-07-02 2022-02-01 The University Of Chicago Polipeptídeo imunogênico isolado, composição imunogênica e seu uso
SG10201604554WA (en) 2011-06-08 2016-07-28 Emd Millipore Corp Chromatography matrices including novel staphylococcus aureus protein a based ligands
US9556281B2 (en) * 2011-08-15 2017-01-31 The University Of Chicago Compositions and methods related to antibodies to staphylococcal protein A
US20160074497A1 (en) * 2013-05-03 2016-03-17 The University Of Chicago Staphylococcus live cell vaccines
GB201506868D0 (en) * 2015-04-22 2015-06-03 Ucb Biopharma Sprl Method for protein purification
WO2025036605A1 (en) * 2023-08-14 2025-02-20 Cytiva Bioprocess R&D Ab Vh3 binding separation matrix and methods for using the same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5831012A (en) * 1994-01-14 1998-11-03 Pharmacia & Upjohn Aktiebolag Bacterial receptor structures

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8300693L (sv) * 1983-02-09 1984-08-10 Sven Lofdahl Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US4879378A (en) 1989-03-30 1989-11-07 Union Carbide Chemicals And Plastics Company Inc. Polysiloxanes with pendant sterically hindered phenol moiety connected to the silicon atom via a carbonylyoxy-containing link
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5198531A (en) 1991-06-14 1993-03-30 Research Diagnostic Antibodies Polymeric resin for peptide synthesis
US5240680A (en) 1991-12-19 1993-08-31 Chiron Corporation Automated apparatus for use in peptide synthesis
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US5891438A (en) * 1992-10-30 1999-04-06 The Regents Of The University Of California Method for stimulating production of variable region gene family restricted antibodies through B-cell superantigen vaccination
EP2258726A1 (en) 1995-06-14 2010-12-08 The Regents of the University of California High affinity human antibodies to c-erbB-2
US6031071A (en) 1996-01-24 2000-02-29 Biophage, Inc. Methods of generating novel peptides
WO1997036614A1 (en) * 1996-03-29 1997-10-09 Terman David S Polymerized staphylococcal protein a for treatment of diseases
US6013763A (en) * 1996-06-04 2000-01-11 Genentech, Inc. Peptide variants of protein A

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5831012A (en) * 1994-01-14 1998-11-03 Pharmacia & Upjohn Aktiebolag Bacterial receptor structures

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
OLSZEWSKI K A ET AL. PROTEINS STRU. FUNC. & GEN. (1996) P286 *
ROBEN P W ET AL. JNL. OF IMMUN. (1995) VOL.154(12),PP6437-45 *

Also Published As

Publication number Publication date
EP2017343A3 (en) 2009-01-28
EP1181052A1 (en) 2002-02-27
EP2017343A2 (en) 2009-01-21
US20060205016A1 (en) 2006-09-14
EP1181052A4 (en) 2004-08-11
AU5019100A (en) 2000-12-05
WO2000069457A1 (en) 2000-11-23
CA2374013A1 (en) 2000-11-23
JP2002544237A (ja) 2002-12-24

Similar Documents

Publication Publication Date Title
AU777005B2 (en) Protein A based binding domains with desirable activities
JP5159841B2 (ja) 新規のFabフラグメントライブラリーおよびそれらの使用方法
JP5461643B2 (ja) ヒト抗体及びタンパク質
JP5431920B2 (ja) 受容体チロシンキナーゼalkの細胞外ドメインに結合する抗体
EP2989204B1 (en) Isolation of therapeutic target specific vnar domains to icosl
JP2022523710A (ja) Cd44に特異的な抗体
CN114380906B (zh) 一种抗il-17a的单域抗体及其用途
KR100328112B1 (ko) 류마토이드관절염병원관련관절염성펩티드에대항하는면역보호유도에유용한백신조성물과방법
US7935793B2 (en) Treatment of inflammatory bowel diseases with anti-IP-10 antibodies
JPH08501925A (ja) 糖蛋白pに対するモノクローナル抗体
JP3862752B2 (ja) 全身性エリテマトーデス治療用の合成ベプチドおよびこれを含有する薬剤組成物
US7163686B1 (en) Protein A based binding domains with desirable activities
KR20030083698A (ko) 물질
EP0762881A1 (en) Method and reagents for the treatment of rheumatoid arthritis
US6613536B1 (en) Synthetic peptides and pharmaceutical compositions comprising them for the treatment of systemic lupus erythematosus
Chen et al. Protection of IgE-mediated allergic sensitization by active immunization with IgE loops constrained in GFP protein scaffold
KR100506118B1 (ko) 수막염균증 백신 조성물
Silver-man B-Cell Superantigens: An Overview of Structural, Evolutionary, and Immunobiologic Considerations
Rock Structure-function analyses of antigen-specific T cell receptors
MXPA99008621A (es) Peptidos de union a ctla-4, inmunoterapeuticos