AU767193B2 - Mutations responsible for attenuation in measles virus or human respiratory syncytial virus subgroup B - Google Patents

Mutations responsible for attenuation in measles virus or human respiratory syncytial virus subgroup B Download PDF

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Publication number
AU767193B2
AU767193B2 AU31095/99A AU3109599A AU767193B2 AU 767193 B2 AU767193 B2 AU 767193B2 AU 31095/99 A AU31095/99 A AU 31095/99A AU 3109599 A AU3109599 A AU 3109599A AU 767193 B2 AU767193 B2 AU 767193B2
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AU
Australia
Prior art keywords
virus
vaccine
gene
rsv
nucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU31095/99A
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English (en)
Other versions
AU3109599A (en
Inventor
Deborah A. Buonagurio
Valerie B. Randolph
Mohinderjit S. Sidhu
Stephen A. Udem
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
Wyeth Holdings LLC
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Holdings LLC, Wyeth LLC filed Critical Wyeth Holdings LLC
Publication of AU3109599A publication Critical patent/AU3109599A/en
Assigned to WYETH HOLDINGS CORPORATION reassignment WYETH HOLDINGS CORPORATION Amend patent request/document other than specification (104) Assignors: AMERICAN CYANAMID COMPANY
Application granted granted Critical
Publication of AU767193B2 publication Critical patent/AU767193B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18422—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU31095/99A 1998-03-26 1999-03-22 Mutations responsible for attenuation in measles virus or human respiratory syncytial virus subgroup B Ceased AU767193B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7946698P 1998-03-26 1998-03-26
US60/079466 1998-03-26
PCT/US1999/006225 WO1999049017A2 (en) 1998-03-26 1999-03-22 Mutations responsible for attenuation in measles virus or human respiratory syncytial virus subgroup b

Publications (2)

Publication Number Publication Date
AU3109599A AU3109599A (en) 1999-10-18
AU767193B2 true AU767193B2 (en) 2003-11-06

Family

ID=22150746

Family Applications (1)

Application Number Title Priority Date Filing Date
AU31095/99A Ceased AU767193B2 (en) 1998-03-26 1999-03-22 Mutations responsible for attenuation in measles virus or human respiratory syncytial virus subgroup B

Country Status (9)

Country Link
EP (1) EP1064358A2 (xx)
JP (1) JP2002507408A (xx)
KR (1) KR20010080863A (xx)
CN (2) CN1177927C (xx)
AU (1) AU767193B2 (xx)
BR (1) BR9909076A (xx)
CA (1) CA2323927A1 (xx)
IL (1) IL138681A0 (xx)
WO (1) WO1999049017A2 (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002000694A2 (en) * 2000-06-23 2002-01-03 American Cyanamid Company Modified morbillivirus v proteins
DE60233038D1 (de) * 2002-06-20 2009-09-03 Pasteur Institut Infektiöse cDNA eines zugelassenen Impfstammes des Masern Virus. Verwendung in immunogenen Zusammensetzungen
EP1613345B1 (en) * 2003-03-28 2010-05-26 MedImmune, LLC Compositions and methods involving respiratory syncytial virus subgroup b strain 9320
JPWO2008065752A1 (ja) * 2006-11-30 2010-03-04 国立大学法人北海道大学 ｄｉＲＮＡを有効成分とする免疫治療用薬剤
MX2011004719A (es) 2008-11-05 2011-05-31 Merck Sharp & Dohme Virus sincitial respiratorio vivo atenuado.
EP2420242A1 (en) 2010-08-20 2012-02-22 Lauer, Ulrich M. Oncolytic measles virus
JP6453063B2 (ja) * 2014-12-02 2019-01-16 国立大学法人北海道大学 アジュバント組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3045581B2 (ja) * 1991-10-14 2000-05-29 社団法人北里研究所 麻疹ワクチンウイルス株同定方法
TW275632B (xx) * 1992-04-21 1996-05-11 American Cyanamid Co
AU4427897A (en) * 1996-09-27 1998-04-17 American Cyanamid Company 3' genomic promoter region and polymerase gene mutations responsible for att enuation in viruses of the order designated mononegavirales

Also Published As

Publication number Publication date
CA2323927A1 (en) 1999-09-30
IL138681A0 (en) 2001-10-31
AU3109599A (en) 1999-10-18
BR9909076A (pt) 2000-12-05
KR20010080863A (ko) 2001-08-25
EP1064358A2 (en) 2001-01-03
CN1177927C (zh) 2004-12-01
CN1600852A (zh) 2005-03-30
CN1294628A (zh) 2001-05-09
JP2002507408A (ja) 2002-03-12
WO1999049017A3 (en) 1999-12-16
WO1999049017A2 (en) 1999-09-30

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Legal Events

Date Code Title Description
TC Change of applicant's name (sec. 104)

Owner name: WYETH HOLDINGS CORPORATION

Free format text: FORMER NAME: AMERICAN CYANAMID COMPANY

FGA Letters patent sealed or granted (standard patent)