AU762240B2 - Melanoma associated antigen (HMW-MAA) defined by a monoclonal antibody - Google Patents
Melanoma associated antigen (HMW-MAA) defined by a monoclonal antibody Download PDFInfo
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- AU762240B2 AU762240B2 AU68837/00A AU6883700A AU762240B2 AU 762240 B2 AU762240 B2 AU 762240B2 AU 68837/00 A AU68837/00 A AU 68837/00A AU 6883700 A AU6883700 A AU 6883700A AU 762240 B2 AU762240 B2 AU 762240B2
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- Prior art keywords
- antibody
- epitope
- binding
- amino acids
- maa
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008223 sterile water Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 231100000057 systemic toxicity Toxicity 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 108010044292 tryptophyltyrosine Proteins 0.000 description 1
- 210000005239 tubule Anatomy 0.000 description 1
- 230000002476 tumorcidal effect Effects 0.000 description 1
- 108010003137 tyrosyltyrosine Proteins 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000001262 western blot Methods 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3053—Skin, nerves, brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00119—Melanoma antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9902989 | 1999-08-24 | ||
| SE9902989A SE9902989D0 (sv) | 1999-08-24 | 1999-08-24 | Novel compounds |
| PCT/SE2000/001597 WO2001014884A1 (fr) | 1999-08-24 | 2000-08-22 | Antigene associe a un melanome (hmw-maa) defini par un anticorps monoclonal |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU6883700A AU6883700A (en) | 2001-03-19 |
| AU762240B2 true AU762240B2 (en) | 2003-06-19 |
Family
ID=20416736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU68837/00A Ceased AU762240B2 (en) | 1999-08-24 | 2000-08-22 | Melanoma associated antigen (HMW-MAA) defined by a monoclonal antibody |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1206702A1 (fr) |
| AU (1) | AU762240B2 (fr) |
| CA (1) | CA2381099A1 (fr) |
| NZ (1) | NZ517132A (fr) |
| SE (1) | SE9902989D0 (fr) |
| WO (1) | WO2001014884A1 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10328121A1 (de) * | 2003-06-23 | 2005-02-03 | Biolife Science Forschungs- und Entwicklungs-GbmH | Passive Immuntherapie gegen malignes Melanom |
| SE0402025D0 (sv) * | 2004-08-13 | 2004-08-13 | Active Biotech Ab | Treatment of hyperproliferative disease with superantigens in combination with another anticancer agent |
| AT502292B1 (de) | 2005-05-11 | 2010-04-15 | Avir Green Hills Biotechnology | Melanomdiagnose |
| CN118420712A (zh) * | 2023-02-01 | 2024-08-02 | 上海健信生物医药科技有限公司 | 一种三特异性抗体技术平台及其应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997002479A2 (fr) * | 1995-06-30 | 1997-01-23 | Yale University | Anticorps anti-tumoraux monoclonaux humains |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9700291D0 (sv) * | 1997-01-31 | 1997-01-31 | Pharmacia & Upjohn Ab | Selection method and prodcts resulting therefrom |
-
1999
- 1999-08-24 SE SE9902989A patent/SE9902989D0/xx unknown
-
2000
- 2000-08-22 EP EP00957184A patent/EP1206702A1/fr not_active Withdrawn
- 2000-08-22 CA CA002381099A patent/CA2381099A1/fr not_active Abandoned
- 2000-08-22 WO PCT/SE2000/001597 patent/WO2001014884A1/fr not_active Application Discontinuation
- 2000-08-22 AU AU68837/00A patent/AU762240B2/en not_active Ceased
- 2000-08-22 NZ NZ517132A patent/NZ517132A/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997002479A2 (fr) * | 1995-06-30 | 1997-01-23 | Yale University | Anticorps anti-tumoraux monoclonaux humains |
Non-Patent Citations (2)
| Title |
|---|
| NORONHA EJ ET AL (1998) J. IMMUNOL. 161(6) P.2968-76 * |
| XIAOHONG CAI ET AL. (1997) PROC. NAT. ACAD. SCI, 94 P9261-66 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1206702A1 (fr) | 2002-05-22 |
| AU6883700A (en) | 2001-03-19 |
| CA2381099A1 (fr) | 2001-03-01 |
| WO2001014884A1 (fr) | 2001-03-01 |
| NZ517132A (en) | 2003-10-31 |
| SE9902989D0 (sv) | 1999-08-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |