AU760250B2 - New benzimidazolone-, benzoxazolone-, or benzothiazolone derivatives as ion channel modulating agents - Google Patents

New benzimidazolone-, benzoxazolone-, or benzothiazolone derivatives as ion channel modulating agents Download PDF

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Publication number
AU760250B2
AU760250B2 AU15498/00A AU1549800A AU760250B2 AU 760250 B2 AU760250 B2 AU 760250B2 AU 15498/00 A AU15498/00 A AU 15498/00A AU 1549800 A AU1549800 A AU 1549800A AU 760250 B2 AU760250 B2 AU 760250B2
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disease
disorder
condition
channels
benzimidazolone derivative
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AU15498/00A
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AU1549800A (en
Inventor
Palle Christophersen
Bo Skaaning Jensen
Dorte Strobaek
Lene Teuber
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NTG Nordic Transport Group AS
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Neurosearch AS
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C—CHEMISTRY; METALLURGY
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    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • C—CHEMISTRY; METALLURGY
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    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
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    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
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AU15498/00A 1998-12-04 1999-12-03 New benzimidazolone-, benzoxazolone-, or benzothiazolone derivatives as ion channel modulating agents Ceased AU760250B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA199801610 1998-12-04
DKPA199801610 1998-12-04
PCT/DK1999/000681 WO2000034248A1 (en) 1998-12-04 1999-12-03 New benzimidazolone-, benzoxazolone-, or benzothiazolone derivatives as ion channel modulating agents

Publications (2)

Publication Number Publication Date
AU1549800A AU1549800A (en) 2000-06-26
AU760250B2 true AU760250B2 (en) 2003-05-08

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AU15498/00A Ceased AU760250B2 (en) 1998-12-04 1999-12-03 New benzimidazolone-, benzoxazolone-, or benzothiazolone derivatives as ion channel modulating agents

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US (2) US6624186B2 (enExample)
EP (1) EP1144387A1 (enExample)
JP (1) JP2002531552A (enExample)
CN (1) CN1177831C (enExample)
AU (1) AU760250B2 (enExample)
CA (1) CA2349616A1 (enExample)
NZ (1) NZ511334A (enExample)
WO (1) WO2000034248A1 (enExample)

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CN105294591B (zh) * 2015-11-17 2017-05-10 河南大学 一种高立体和高对映选择性噁唑啉二酮类化合物、制备方法及其应用
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US20020055526A1 (en) 2002-05-09
CN1177831C (zh) 2004-12-01
JP2002531552A (ja) 2002-09-24
CN1329601A (zh) 2002-01-02
AU1549800A (en) 2000-06-26
US20040029937A1 (en) 2004-02-12
EP1144387A1 (en) 2001-10-17
CA2349616A1 (en) 2000-06-15
NZ511334A (en) 2003-06-30
WO2000034248A1 (en) 2000-06-15

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