AU743102B2 - Pharmaceutical substance containing various vitamin K-dependent factors - Google Patents

Pharmaceutical substance containing various vitamin K-dependent factors Download PDF

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Publication number
AU743102B2
AU743102B2 AU92449/98A AU9244998A AU743102B2 AU 743102 B2 AU743102 B2 AU 743102B2 AU 92449/98 A AU92449/98 A AU 92449/98A AU 9244998 A AU9244998 A AU 9244998A AU 743102 B2 AU743102 B2 AU 743102B2
Authority
AU
Australia
Prior art keywords
factor
preparation according
protein
preparation
factors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU92449/98A
Other languages
English (en)
Other versions
AU9244998A (en
Inventor
Yendra Linnau
Hans Peter Schwarz
Peter Turecek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter AG
Original Assignee
Baxter AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter AG filed Critical Baxter AG
Publication of AU9244998A publication Critical patent/AU9244998A/en
Application granted granted Critical
Publication of AU743102B2 publication Critical patent/AU743102B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AU92449/98A 1997-09-19 1998-09-17 Pharmaceutical substance containing various vitamin K-dependent factors Ceased AU743102B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT1591/97 1997-09-19
AT0159197A AT409334B (de) 1997-09-19 1997-09-19 Pharmazeutisches präparat enthaltend vitamin k-abhängige einzelfaktoren
PCT/AT1998/000224 WO1999015196A1 (de) 1997-09-19 1998-09-17 Pharmazeutisches präparat enthaltend vitamin k-abhängige einzelfaktoren

Publications (2)

Publication Number Publication Date
AU9244998A AU9244998A (en) 1999-04-12
AU743102B2 true AU743102B2 (en) 2002-01-17

Family

ID=3516739

Family Applications (1)

Application Number Title Priority Date Filing Date
AU92449/98A Ceased AU743102B2 (en) 1997-09-19 1998-09-17 Pharmaceutical substance containing various vitamin K-dependent factors

Country Status (10)

Country Link
EP (1) EP1015020A1 (no)
JP (1) JP2001517636A (no)
AT (1) AT409334B (no)
AU (1) AU743102B2 (no)
BR (1) BR9812222A (no)
CA (1) CA2304396A1 (no)
HU (1) HUP0003681A1 (no)
NO (1) NO20001415L (no)
SK (1) SK4022000A3 (no)
WO (1) WO1999015196A1 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1458408B1 (en) 2001-12-21 2009-04-15 Novo Nordisk Health Care AG Liquid composition of factor vii polypeptides
AU2003213146A1 (en) * 2002-03-08 2003-09-22 Eli Lilly And Company Activated protein c formulations
CN101912601B (zh) 2002-06-21 2012-08-29 诺和诺德医疗保健公司 因子vii多肽的稳定化固体组合物
US7897734B2 (en) 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
WO2004103398A1 (en) 2003-05-23 2004-12-02 Novo Nordisk Health Care Ag Protein stabilization in solution
JP4658041B2 (ja) 2003-06-25 2011-03-23 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト Ｖｉｉ因子ポリペプチドの液体組成物
KR20120104619A (ko) 2003-08-14 2012-09-21 노보 노르디스크 헬스 케어 악티엔게젤샤프트 인자 ｖｉｉ 폴리펩티드의 액상 수성 약학적 조성물
EP2311437A1 (en) 2003-12-19 2011-04-20 Novo Nordisk Health Care AG Stabilised compositions of factor VII polypeptides
CN101151533A (zh) * 2005-02-16 2008-03-26 伊利诺斯大学理事会 基于金属螯合脂质的促凝血剂
ATE505488T1 (de) 2005-03-04 2011-04-15 Univ Illinois Modulator von coagulationskaskaden und fibrinolytischen kaskaden
WO2009046194A2 (en) 2007-10-05 2009-04-09 The Board Of Trustees Of The University Of Illinois Fibrin sealant
WO2009061697A1 (en) 2007-11-09 2009-05-14 The Board Of Trustees Of The University Of Illinois Anticoagulant antagonist and hemophilia procoagulant
CN103221061A (zh) 2010-10-06 2013-07-24 米迪缪尼有限公司 用于治疗止血障碍的因子ii以及纤维蛋白原
DK3579857T3 (da) * 2017-02-09 2022-06-07 Csl Behring Gmbh Et blodkoagulationsfaktorerstatningsprodukt til anvendelse ved behandling eller profylakse af blødninger

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0617049A1 (en) * 1992-03-22 1994-09-28 SCLAVO S.p.A. Process for the isolation of highly purified factors IX, X and II from prothrombin complex or human plasma
EP0700684A2 (de) * 1994-08-26 1996-03-13 BEHRINGWERKE Aktiengesellschaft Zusammensetzungen, enthaltend Prothrombinkomplex-Konzentrat und wenigstens eine weitere Komponente das die Blutgerrinnung fördert, als Gegenmittel für Blut-Anticoagulanzien

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8729822D0 (en) * 1987-12-22 1988-02-03 Central Blood Lab Authority Chemical process
DE4342132C1 (de) * 1993-12-10 1994-11-03 Octapharma Ag Verfahren zur Herstellung virusinaktivierte Vitamin K abhängige Plasmakomponenten sowie Protein C und Protein S enthaltender Mittel durch Membran-Chromatographie
DK0796623T3 (da) * 1996-03-20 2005-08-01 Baxter Ag Farmaceutisk præparat til behandling af blodkoagulationslidelser

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0617049A1 (en) * 1992-03-22 1994-09-28 SCLAVO S.p.A. Process for the isolation of highly purified factors IX, X and II from prothrombin complex or human plasma
EP0700684A2 (de) * 1994-08-26 1996-03-13 BEHRINGWERKE Aktiengesellschaft Zusammensetzungen, enthaltend Prothrombinkomplex-Konzentrat und wenigstens eine weitere Komponente das die Blutgerrinnung fördert, als Gegenmittel für Blut-Anticoagulanzien

Also Published As

Publication number Publication date
BR9812222A (pt) 2000-07-18
HUP0003681A1 (hu) 2001-02-28
SK4022000A3 (en) 2000-09-12
AU9244998A (en) 1999-04-12
JP2001517636A (ja) 2001-10-09
WO1999015196A1 (de) 1999-04-01
NO20001415D0 (no) 2000-03-17
ATA159197A (de) 2001-12-15
EP1015020A1 (de) 2000-07-05
AT409334B (de) 2002-07-25
CA2304396A1 (en) 1999-04-01
NO20001415L (no) 2000-05-19

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired