AU730216B2 - Solid coprecipitates for enhanced bioavailability of lipophilic substances - Google Patents
Solid coprecipitates for enhanced bioavailability of lipophilic substances Download PDFInfo
- Publication number
- AU730216B2 AU730216B2 AU42373/97A AU4237397A AU730216B2 AU 730216 B2 AU730216 B2 AU 730216B2 AU 42373/97 A AU42373/97 A AU 42373/97A AU 4237397 A AU4237397 A AU 4237397A AU 730216 B2 AU730216 B2 AU 730216B2
- Authority
- AU
- Australia
- Prior art keywords
- composition
- tpgs
- solid
- coprecipitate
- lipophilic substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL119176 | 1996-09-01 | ||
| IL11917696A IL119176A (en) | 1996-09-01 | 1996-09-01 | Soluble coprecipitates for enhanced oral bioavailability of lipophilic substances |
| US08/833076 | 1997-04-02 | ||
| US08/833,076 US5891469A (en) | 1997-04-02 | 1997-04-02 | Solid Coprecipitates for enhanced bioavailability of lipophilic substances |
| PCT/US1997/015072 WO1998008490A1 (en) | 1996-09-01 | 1997-08-27 | Solid coprecipitates for enhanced bioavailability of lipophilic substances |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU4237397A AU4237397A (en) | 1998-03-19 |
| AU730216B2 true AU730216B2 (en) | 2001-03-01 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU42373/97A Ceased AU730216B2 (en) | 1996-09-01 | 1997-08-27 | Solid coprecipitates for enhanced bioavailability of lipophilic substances |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1017366A4 (OSRAM) |
| JP (1) | JP2001523221A (OSRAM) |
| AU (1) | AU730216B2 (OSRAM) |
| CA (1) | CA2264718C (OSRAM) |
| WO (1) | WO1998008490A1 (OSRAM) |
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| US20030220234A1 (en) | 1998-11-02 | 2003-11-27 | Selvaraj Naicker | Deuterated cyclosporine analogs and their use as immunodulating agents |
| US5891845A (en) * | 1997-11-21 | 1999-04-06 | Fuisz Technologies Ltd. | Drug delivery systems utilizing liquid crystal structures |
| IT1298731B1 (it) * | 1998-03-13 | 2000-02-02 | Recordati Chem Pharm | Composizioni farmaceutiche contenenti complessi di inclusione con melatonina |
| US6241969B1 (en) * | 1998-06-26 | 2001-06-05 | Elan Corporation Plc | Aqueous compositions containing corticosteroids for nasal and pulmonary delivery |
| US6200550B1 (en) * | 1998-12-11 | 2001-03-13 | Q-Pharma, Inc. | Oral care compositions comprising coenzyme Q10 |
| US6632443B2 (en) | 2000-02-23 | 2003-10-14 | National Research Council Of Canada | Water-soluble compositions of bioactive lipophilic compounds |
| US6045826A (en) | 1999-04-02 | 2000-04-04 | National Research Council Of Canada | Water-soluble compositions of bioactive lipophilic compounds |
| US20080070981A1 (en) | 2000-02-23 | 2008-03-20 | Henryk Borowy-Borowski | Water-soluble compositions of bioactive lipophilic compounds |
| AR025587A1 (es) | 1999-09-13 | 2002-12-04 | Hoffmann La Roche | Formulaciones en dispersion que contienen inhibidores de lipasa |
| EP1246668B1 (en) * | 1999-12-01 | 2005-11-30 | Natco Pharma Limited | An rapid acting freeze dired oral pharmaceutical composition for treating migraine |
| EP1251858B1 (en) * | 2000-01-20 | 2005-06-08 | Supratek Pharma Inc. | Podophyllotoxin compositions |
| DE10046541A1 (de) * | 2000-09-19 | 2002-03-28 | Knoll Ag | Mechanisch stabile darreichungsformen, enthaltend Ubichinone |
| AR033711A1 (es) * | 2001-05-09 | 2004-01-07 | Novartis Ag | Composiciones farmaceuticas |
| PT1436321E (pt) | 2001-10-19 | 2006-10-31 | Isotechnika Inc | Sintese de analogos de ciclosporina |
| FR2840614B1 (fr) * | 2002-06-07 | 2004-08-27 | Flamel Tech Sa | Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques |
| WO2004050068A1 (en) | 2002-11-29 | 2004-06-17 | Janssen Pharmaceutica N.V. | Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base |
| JP2006518380A (ja) | 2003-01-31 | 2006-08-10 | スミスクライン・ビーチャム・コーポレイション | 固体分散体組成物 |
| CA2516448A1 (en) * | 2003-02-19 | 2004-09-02 | H. Lundbeck A/S | Method for preparation of an agglomerate using melt agglomeration |
| US20050096365A1 (en) * | 2003-11-03 | 2005-05-05 | David Fikstad | Pharmaceutical compositions with synchronized solubilizer release |
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| US5179122A (en) * | 1991-02-11 | 1993-01-12 | Eastman Kodak Company | Nutritional supplement containing vitamin e |
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-
1997
- 1997-08-27 WO PCT/US1997/015072 patent/WO1998008490A1/en not_active Ceased
- 1997-08-27 AU AU42373/97A patent/AU730216B2/en not_active Ceased
- 1997-08-27 EP EP97940639A patent/EP1017366A4/en not_active Withdrawn
- 1997-08-27 JP JP51187998A patent/JP2001523221A/ja not_active Ceased
- 1997-08-27 CA CA002264718A patent/CA2264718C/en not_active Expired - Fee Related
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| US3102078A (en) * | 1961-01-13 | 1963-08-27 | Eastman Kodak Co | Water-dispersible vitamin preparations |
| US5179122A (en) * | 1991-02-11 | 1993-01-12 | Eastman Kodak Company | Nutritional supplement containing vitamin e |
| US5430021A (en) * | 1994-03-18 | 1995-07-04 | Pharmavene, Inc. | Hydrophobic drug delivery systems |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001523221A (ja) | 2001-11-20 |
| CA2264718A1 (en) | 1998-03-05 |
| CA2264718C (en) | 2006-05-30 |
| EP1017366A4 (en) | 2006-03-22 |
| EP1017366A1 (en) | 2000-07-12 |
| WO1998008490A1 (en) | 1998-03-05 |
| AU4237397A (en) | 1998-03-19 |
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