AU687042B2 - Antitumor compositions and methods of treatment - Google Patents

Antitumor compositions and methods of treatment Download PDF

Info

Publication number
AU687042B2
AU687042B2 AU63638/94A AU6363894A AU687042B2 AU 687042 B2 AU687042 B2 AU 687042B2 AU 63638/94 A AU63638/94 A AU 63638/94A AU 6363894 A AU6363894 A AU 6363894A AU 687042 B2 AU687042 B2 AU 687042B2
Authority
AU
Australia
Prior art keywords
compound
document
pharmaceutically acceptable
formula
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU63638/94A
Other languages
English (en)
Other versions
AU6363894A (en
Inventor
Cora Sue Grossman
Gerald Burr +di Grundey
James Jeffry Howbert
James Edward Ray
John Eldon Toth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU6363894A publication Critical patent/AU6363894A/en
Application granted granted Critical
Publication of AU687042B2 publication Critical patent/AU687042B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU63638/94A 1993-03-10 1994-03-10 Antitumor compositions and methods of treatment Ceased AU687042B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2909593A 1993-03-10 1993-03-10
US029095 1993-03-10
PCT/US1994/002606 WO1994020101A1 (en) 1993-03-10 1994-03-10 Antitumor compositions and methods of treatment

Publications (2)

Publication Number Publication Date
AU6363894A AU6363894A (en) 1994-09-26
AU687042B2 true AU687042B2 (en) 1998-02-19

Family

ID=21847185

Family Applications (1)

Application Number Title Priority Date Filing Date
AU63638/94A Ceased AU687042B2 (en) 1993-03-10 1994-03-10 Antitumor compositions and methods of treatment

Country Status (20)

Country Link
EP (1) EP0614887B1 (ko)
JP (1) JPH08507532A (ko)
KR (1) KR960700710A (ko)
AT (1) ATE154345T1 (ko)
AU (1) AU687042B2 (ko)
BR (1) BR9405997A (ko)
CA (1) CA2157801A1 (ko)
CZ (1) CZ232695A3 (ko)
DE (1) DE69403695T2 (ko)
DK (1) DK0614887T3 (ko)
ES (1) ES2102774T3 (ko)
FI (1) FI954213A (ko)
GR (1) GR3023827T3 (ko)
HU (1) HU218660B (ko)
NO (1) NO953557L (ko)
NZ (1) NZ263080A (ko)
PL (1) PL310558A1 (ko)
RU (1) RU2127259C1 (ko)
WO (1) WO1994020101A1 (ko)
ZA (1) ZA941500B (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69708340T2 (de) * 1996-08-22 2002-05-16 Dong Wha Pharm Ind Co Ltd Arylsulfonylimidazolon-derivate als antitumormittel
DE19919793A1 (de) 1999-04-30 2000-11-02 Bayer Ag Neue Sulfonamide
US7282595B2 (en) 2002-11-22 2007-10-16 Eli Lilly And Company Antitumor benzoylsulfonamides

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6294286A (en) * 1985-09-23 1987-03-26 Eli Lilly And Company 1-(substituted Phenyl)-3-(arylsulfonyl) ureas
AU3519893A (en) * 1992-03-13 1993-09-16 Eli Lilly And Company Antitumor compositions and methods of treatment

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1240866B (de) * 1961-06-29 1967-05-24 Heyden Chem Fab Verfahren zur Herstellung von Indolin-6-sulfonylharnstoffen
US5116874A (en) * 1985-09-23 1992-05-26 Eli Lilly And Company Anti-tumor method and compounds
CA1331464C (en) * 1987-05-12 1994-08-16 Eli Lilly And Company Anti-tumor method and compounds
IL98784A0 (en) * 1990-07-17 1992-07-15 Lilly Co Eli Heterocyclyl sulfonamide derivatives,process for their preparation and pharmaceutical compositions containing them

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6294286A (en) * 1985-09-23 1987-03-26 Eli Lilly And Company 1-(substituted Phenyl)-3-(arylsulfonyl) ureas
AU3519893A (en) * 1992-03-13 1993-09-16 Eli Lilly And Company Antitumor compositions and methods of treatment

Also Published As

Publication number Publication date
HUT72897A (en) 1996-06-28
EP0614887A1 (en) 1994-09-14
FI954213A0 (fi) 1995-09-08
CA2157801A1 (en) 1994-09-15
BR9405997A (pt) 1995-12-19
RU2127259C1 (ru) 1999-03-10
PL310558A1 (en) 1995-12-27
FI954213A (fi) 1995-10-11
WO1994020101A1 (en) 1994-09-15
NO953557L (no) 1995-11-02
KR960700710A (ko) 1996-02-24
NO953557D0 (no) 1995-09-08
NZ263080A (en) 1996-12-20
ZA941500B (en) 1995-09-04
ES2102774T3 (es) 1997-08-01
ATE154345T1 (de) 1997-06-15
DE69403695D1 (de) 1997-07-17
JPH08507532A (ja) 1996-08-13
EP0614887B1 (en) 1997-06-11
DK0614887T3 (da) 1997-10-20
HU218660B (hu) 2000-10-28
GR3023827T3 (en) 1997-09-30
DE69403695T2 (de) 1997-10-30
AU6363894A (en) 1994-09-26
CZ232695A3 (en) 1996-01-17
HU9502627D0 (en) 1995-11-28

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired