ATE154345T1 - Indol-sulfonamide als antitumormittel - Google Patents

Indol-sulfonamide als antitumormittel

Info

Publication number
ATE154345T1
ATE154345T1 AT94301671T AT94301671T ATE154345T1 AT E154345 T1 ATE154345 T1 AT E154345T1 AT 94301671 T AT94301671 T AT 94301671T AT 94301671 T AT94301671 T AT 94301671T AT E154345 T1 ATE154345 T1 AT E154345T1
Authority
AT
Austria
Prior art keywords
tumor agents
indolinesulfonamide
indolesulfonamide
chem
derivatives
Prior art date
Application number
AT94301671T
Other languages
English (en)
Inventor
Gerald Burr Grindey
Cora Sue Grossman
James Jeffry Howbert
James Edward Ray
John Eldon Toth
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE154345T1 publication Critical patent/ATE154345T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/40Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
AT94301671T 1993-03-10 1994-03-09 Indol-sulfonamide als antitumormittel ATE154345T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2909593A 1993-03-10 1993-03-10

Publications (1)

Publication Number Publication Date
ATE154345T1 true ATE154345T1 (de) 1997-06-15

Family

ID=21847185

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94301671T ATE154345T1 (de) 1993-03-10 1994-03-09 Indol-sulfonamide als antitumormittel

Country Status (20)

Country Link
EP (1) EP0614887B1 (de)
JP (1) JPH08507532A (de)
KR (1) KR960700710A (de)
AT (1) ATE154345T1 (de)
AU (1) AU687042B2 (de)
BR (1) BR9405997A (de)
CA (1) CA2157801A1 (de)
CZ (1) CZ232695A3 (de)
DE (1) DE69403695T2 (de)
DK (1) DK0614887T3 (de)
ES (1) ES2102774T3 (de)
FI (1) FI954213A (de)
GR (1) GR3023827T3 (de)
HU (1) HU218660B (de)
NO (1) NO953557L (de)
NZ (1) NZ263080A (de)
PL (1) PL310558A1 (de)
RU (1) RU2127259C1 (de)
WO (1) WO1994020101A1 (de)
ZA (1) ZA941500B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2263353C (en) * 1996-08-22 2002-04-23 Dong Wha Pharm. Ind. Co., Ltd. Arylsulfonylimidazolone derivatives as an antitumor agent
DE19919793A1 (de) 1999-04-30 2000-11-02 Bayer Ag Neue Sulfonamide
AU2003290592A1 (en) 2002-11-22 2004-06-18 Eli Lilly And Company Antitumor benzoylsulfonamides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1240866B (de) * 1961-06-29 1967-05-24 Heyden Chem Fab Verfahren zur Herstellung von Indolin-6-sulfonylharnstoffen
GR862353B (en) * 1985-09-23 1987-01-19 Lilly Co Eli Anti-tumor method and compounds
US5116874A (en) * 1985-09-23 1992-05-26 Eli Lilly And Company Anti-tumor method and compounds
CA1331464C (en) * 1987-05-12 1994-08-16 Eli Lilly And Company Anti-tumor method and compounds
IL98784A0 (en) * 1990-07-17 1992-07-15 Lilly Co Eli Heterocyclyl sulfonamide derivatives,process for their preparation and pharmaceutical compositions containing them
US5169860A (en) * 1992-03-13 1992-12-08 Eli Lilly And Company Antitumor compositions and methods of treatment

Also Published As

Publication number Publication date
CA2157801A1 (en) 1994-09-15
ES2102774T3 (es) 1997-08-01
EP0614887A1 (de) 1994-09-14
HU218660B (hu) 2000-10-28
DK0614887T3 (da) 1997-10-20
CZ232695A3 (en) 1996-01-17
KR960700710A (ko) 1996-02-24
DE69403695T2 (de) 1997-10-30
AU687042B2 (en) 1998-02-19
DE69403695D1 (de) 1997-07-17
NO953557L (no) 1995-11-02
EP0614887B1 (de) 1997-06-11
ZA941500B (en) 1995-09-04
PL310558A1 (en) 1995-12-27
GR3023827T3 (en) 1997-09-30
HUT72897A (en) 1996-06-28
RU2127259C1 (ru) 1999-03-10
FI954213A (fi) 1995-10-11
JPH08507532A (ja) 1996-08-13
WO1994020101A1 (en) 1994-09-15
NO953557D0 (no) 1995-09-08
HU9502627D0 (en) 1995-11-28
FI954213A0 (fi) 1995-09-08
AU6363894A (en) 1994-09-26
BR9405997A (pt) 1995-12-19
NZ263080A (en) 1996-12-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee