ZA941500B - Antitumor compositions and methods of treatment - Google Patents

Antitumor compositions and methods of treatment

Info

Publication number
ZA941500B
ZA941500B ZA941500A ZA941500A ZA941500B ZA 941500 B ZA941500 B ZA 941500B ZA 941500 A ZA941500 A ZA 941500A ZA 941500 A ZA941500 A ZA 941500A ZA 941500 B ZA941500 B ZA 941500B
Authority
ZA
South Africa
Prior art keywords
treatment
methods
indolinesulfonamide
indolesulfonamide
chem
Prior art date
Application number
ZA941500A
Other languages
English (en)
Inventor
Gerald Burr Grindey
James Jeffry Howbert
John Eldon Toth
Cora Sue Grossman
James Edward Ray
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA941500B publication Critical patent/ZA941500B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA941500A 1993-03-10 1994-03-03 Antitumor compositions and methods of treatment ZA941500B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2909593A 1993-03-10 1993-03-10

Publications (1)

Publication Number Publication Date
ZA941500B true ZA941500B (en) 1995-09-04

Family

ID=21847185

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA941500A ZA941500B (en) 1993-03-10 1994-03-03 Antitumor compositions and methods of treatment

Country Status (20)

Country Link
EP (1) EP0614887B1 (ko)
JP (1) JPH08507532A (ko)
KR (1) KR960700710A (ko)
AT (1) ATE154345T1 (ko)
AU (1) AU687042B2 (ko)
BR (1) BR9405997A (ko)
CA (1) CA2157801A1 (ko)
CZ (1) CZ232695A3 (ko)
DE (1) DE69403695T2 (ko)
DK (1) DK0614887T3 (ko)
ES (1) ES2102774T3 (ko)
FI (1) FI954213A (ko)
GR (1) GR3023827T3 (ko)
HU (1) HU218660B (ko)
NO (1) NO953557L (ko)
NZ (1) NZ263080A (ko)
PL (1) PL310558A1 (ko)
RU (1) RU2127259C1 (ko)
WO (1) WO1994020101A1 (ko)
ZA (1) ZA941500B (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1021437B1 (en) * 1996-08-22 2001-11-14 Dong Wha Pharmaceutical Industrial Co. Ltd. Arylsulfonylimidazolone derivatives as an antitumor agent
DE19919793A1 (de) 1999-04-30 2000-11-02 Bayer Ag Neue Sulfonamide
AU2003290592A1 (en) * 2002-11-22 2004-06-18 Eli Lilly And Company Antitumor benzoylsulfonamides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1240866B (de) * 1961-06-29 1967-05-24 Heyden Chem Fab Verfahren zur Herstellung von Indolin-6-sulfonylharnstoffen
US5116874A (en) * 1985-09-23 1992-05-26 Eli Lilly And Company Anti-tumor method and compounds
GR862353B (en) * 1985-09-23 1987-01-19 Lilly Co Eli Anti-tumor method and compounds
CA1331464C (en) * 1987-05-12 1994-08-16 Eli Lilly And Company Anti-tumor method and compounds
ZA915371B (en) * 1990-07-17 1993-03-31 Lilly Co Eli Antitumor compositions and methods of treatment
US5169860A (en) * 1992-03-13 1992-12-08 Eli Lilly And Company Antitumor compositions and methods of treatment

Also Published As

Publication number Publication date
HUT72897A (en) 1996-06-28
FI954213A0 (fi) 1995-09-08
JPH08507532A (ja) 1996-08-13
AU6363894A (en) 1994-09-26
PL310558A1 (en) 1995-12-27
NO953557D0 (no) 1995-09-08
HU218660B (hu) 2000-10-28
RU2127259C1 (ru) 1999-03-10
AU687042B2 (en) 1998-02-19
EP0614887A1 (en) 1994-09-14
BR9405997A (pt) 1995-12-19
GR3023827T3 (en) 1997-09-30
EP0614887B1 (en) 1997-06-11
NZ263080A (en) 1996-12-20
HU9502627D0 (en) 1995-11-28
CA2157801A1 (en) 1994-09-15
NO953557L (no) 1995-11-02
WO1994020101A1 (en) 1994-09-15
KR960700710A (ko) 1996-02-24
ES2102774T3 (es) 1997-08-01
DK0614887T3 (da) 1997-10-20
FI954213A (fi) 1995-10-11
ATE154345T1 (de) 1997-06-15
DE69403695D1 (de) 1997-07-17
DE69403695T2 (de) 1997-10-30
CZ232695A3 (en) 1996-01-17

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