AU681703B2 - Derivatives of 1-(2-fluorocyclopropyl)-quinolonecarboxylic acid and 1-(2-fluorocyclopropyl)-naphthyridonecarboxylic acid - Google Patents

Derivatives of 1-(2-fluorocyclopropyl)-quinolonecarboxylic acid and 1-(2-fluorocyclopropyl)-naphthyridonecarboxylic acid Download PDF

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Publication number
AU681703B2
AU681703B2 AU77730/94A AU7773094A AU681703B2 AU 681703 B2 AU681703 B2 AU 681703B2 AU 77730/94 A AU77730/94 A AU 77730/94A AU 7773094 A AU7773094 A AU 7773094A AU 681703 B2 AU681703 B2 AU 681703B2
Authority
AU
Australia
Prior art keywords
acid
oxo
fluorocyclopropyl
derivatives
adjuvants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU77730/94A
Other languages
English (en)
Other versions
AU7773094A (en
Inventor
Stefan Dr. Bohm
Klaus-Dieter Dr. Bremm
Rainer dr. Endermann
Rolf Dr. Grosser
Karl Georg Dr. Metzger
Uwe Dr. Petersen
Thomas Dr. Schenke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of AU7773094A publication Critical patent/AU7773094A/en
Application granted granted Critical
Publication of AU681703B2 publication Critical patent/AU681703B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU77730/94A 1993-11-16 1994-11-09 Derivatives of 1-(2-fluorocyclopropyl)-quinolonecarboxylic acid and 1-(2-fluorocyclopropyl)-naphthyridonecarboxylic acid Ceased AU681703B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4339134A DE4339134A1 (de) 1993-11-16 1993-11-16 1-(2-Fluorcyclopropyl)-chinolon- und -naphthyridoncarbonsäure-Derivate
DE4339134 1993-11-16

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU25599/97A Division AU2559997A (en) 1993-11-16 1997-06-18 Derivatives of 1-(2-fluorocyclopropyl)-quinolonecarboxylic acid and 1-(2-fluorocyclopropyl)-naphthyridonecarboxylic acid

Publications (2)

Publication Number Publication Date
AU7773094A AU7773094A (en) 1995-05-25
AU681703B2 true AU681703B2 (en) 1997-09-04

Family

ID=6502741

Family Applications (2)

Application Number Title Priority Date Filing Date
AU77730/94A Ceased AU681703B2 (en) 1993-11-16 1994-11-09 Derivatives of 1-(2-fluorocyclopropyl)-quinolonecarboxylic acid and 1-(2-fluorocyclopropyl)-naphthyridonecarboxylic acid
AU25599/97A Abandoned AU2559997A (en) 1993-11-16 1997-06-18 Derivatives of 1-(2-fluorocyclopropyl)-quinolonecarboxylic acid and 1-(2-fluorocyclopropyl)-naphthyridonecarboxylic acid

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU25599/97A Abandoned AU2559997A (en) 1993-11-16 1997-06-18 Derivatives of 1-(2-fluorocyclopropyl)-quinolonecarboxylic acid and 1-(2-fluorocyclopropyl)-naphthyridonecarboxylic acid

Country Status (27)

Country Link
US (1) US5545642A (enrdf_load_html_response)
EP (1) EP0653425A1 (enrdf_load_html_response)
JP (1) JPH07188230A (enrdf_load_html_response)
KR (1) KR950014114A (enrdf_load_html_response)
CN (1) CN1106412A (enrdf_load_html_response)
AU (2) AU681703B2 (enrdf_load_html_response)
BG (1) BG62003B1 (enrdf_load_html_response)
CA (1) CA2135548A1 (enrdf_load_html_response)
CO (1) CO4180605A1 (enrdf_load_html_response)
CZ (1) CZ280594A3 (enrdf_load_html_response)
DE (1) DE4339134A1 (enrdf_load_html_response)
EE (1) EE9400240A (enrdf_load_html_response)
FI (1) FI945360A7 (enrdf_load_html_response)
HR (1) HRP940833A2 (enrdf_load_html_response)
HU (1) HUT70175A (enrdf_load_html_response)
IL (1) IL111624A0 (enrdf_load_html_response)
LV (1) LV11328B (enrdf_load_html_response)
NO (1) NO302367B1 (enrdf_load_html_response)
NZ (1) NZ264905A (enrdf_load_html_response)
PE (1) PE32395A1 (enrdf_load_html_response)
PL (1) PL305862A1 (enrdf_load_html_response)
RU (1) RU94040885A (enrdf_load_html_response)
SK (1) SK137194A3 (enrdf_load_html_response)
SV (1) SV1994000064A (enrdf_load_html_response)
TW (1) TW273547B (enrdf_load_html_response)
YU (1) YU65494A (enrdf_load_html_response)
ZA (1) ZA949052B (enrdf_load_html_response)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0664288A1 (en) * 1992-10-09 1995-07-26 Chugai Seiyaku Kabushiki Kaisha Fluoroquinoline derivative
ATE386511T1 (de) * 1995-12-22 2008-03-15 Nagase Chemtex Corp Wirkstoff gegen helicobacter pylori
WO1998058928A1 (fr) * 1997-06-23 1998-12-30 Yoshitomi Pharmaceutical Industries, Ltd. Agent prophylactique ou therapeutique contre des maladies attribuables a une infection par des helicobacters
DE10108750A1 (de) 2001-02-23 2002-09-05 Bayer Ag Verbessertes Verfahren zur Herstellung von Fluorchinoloncarbonsäuren
US7915418B2 (en) * 2003-06-06 2011-03-29 Daiichi Pharmaceutical Co., Ltd. Intermediates and process for the production of optically active quinolonecarboxylic acid derivatives

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0424850A1 (en) * 1989-10-23 1991-05-02 Korea Research Institute Of Chemical Technology Quinolone compounds and a process for their preparation
EP0520277A2 (de) * 1991-06-27 1992-12-30 Bayer Ag 7-Azaisoindolinyl-chinolon- und naphthyridoncarbonsäure-Derivate
EP0550016A1 (en) * 1991-12-31 1993-07-07 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and processes for preparing same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5274167A (en) * 1989-01-26 1993-12-28 Bayer Aktiengesellschaft Polymeriable optically active (meth) acrylic acid derivatives
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
KR910009331B1 (ko) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 디아자비시클로아민 화합물과 그의 제조방법
KR910009333B1 (ko) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법
CA2110260C (en) * 1991-05-28 2001-12-04 Isao Hayakawa Pyridonecarboxylic acid derivatives
WO1994025464A1 (en) * 1993-04-24 1994-11-10 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and process for preparing the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0424850A1 (en) * 1989-10-23 1991-05-02 Korea Research Institute Of Chemical Technology Quinolone compounds and a process for their preparation
EP0520277A2 (de) * 1991-06-27 1992-12-30 Bayer Ag 7-Azaisoindolinyl-chinolon- und naphthyridoncarbonsäure-Derivate
EP0550016A1 (en) * 1991-12-31 1993-07-07 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and processes for preparing same

Also Published As

Publication number Publication date
SV1994000064A (es) 1995-05-25
EE9400240A (et) 1996-02-15
FI945360L (fi) 1995-05-17
ZA949052B (en) 1995-07-19
CA2135548A1 (en) 1995-05-17
PE32395A1 (es) 1995-12-15
KR950014114A (ko) 1995-06-15
LV11328B (en) 1996-12-20
NZ264905A (en) 1995-11-27
DE4339134A1 (de) 1995-05-18
LV11328A (lv) 1996-06-20
BG62003B1 (bg) 1998-12-30
NO944365D0 (no) 1994-11-15
BG99179A (en) 1995-07-28
US5545642A (en) 1996-08-13
HRP940833A2 (en) 1996-12-31
AU2559997A (en) 1997-09-04
RU94040885A (ru) 1996-11-20
HU9403288D0 (en) 1995-01-30
SK137194A3 (en) 1995-06-07
CZ280594A3 (en) 1995-08-16
AU7773094A (en) 1995-05-25
JPH07188230A (ja) 1995-07-25
FI945360A0 (fi) 1994-11-14
IL111624A0 (en) 1995-01-24
CN1106412A (zh) 1995-08-09
EP0653425A1 (de) 1995-05-17
TW273547B (enrdf_load_html_response) 1996-04-01
NO944365L (no) 1995-05-18
PL305862A1 (en) 1995-05-29
YU65494A (sh) 1997-09-30
FI945360A7 (fi) 1995-05-17
HUT70175A (en) 1995-09-28
CO4180605A1 (es) 1995-06-07
NO302367B1 (no) 1998-02-23

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Legal Events

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired