AU636678B2 - Nucleoside derivatives - Google Patents
Nucleoside derivativesInfo
- Publication number
- AU636678B2 AU636678B2 AU66192/90A AU6619290A AU636678B2 AU 636678 B2 AU636678 B2 AU 636678B2 AU 66192/90 A AU66192/90 A AU 66192/90A AU 6619290 A AU6619290 A AU 6619290A AU 636678 B2 AU636678 B2 AU 636678B2
- Authority
- AU
- Australia
- Prior art keywords
- mmol
- added
- dideoxy
- pent
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898925037A GB8925037D0 (en) | 1989-11-06 | 1989-11-06 | Nucleoside derivatives |
GB898925039A GB8925039D0 (en) | 1989-11-06 | 1989-11-06 | Nucleoside derivatives |
GB8925037 | 1989-11-06 | ||
GB8925039 | 1989-11-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
AU6619290A AU6619290A (en) | 1991-05-31 |
AU636678B2 true AU636678B2 (en) | 1993-05-06 |
Family
ID=26296164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU66192/90A Ceased AU636678B2 (en) | 1989-11-06 | 1990-11-06 | Nucleoside derivatives |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0500610A1 (de) |
JP (1) | JPH05501404A (de) |
AU (1) | AU636678B2 (de) |
CA (1) | CA2073063A1 (de) |
FI (1) | FI922014A0 (de) |
OA (1) | OA09697A (de) |
WO (1) | WO1991006554A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6458772B1 (en) * | 1909-10-07 | 2002-10-01 | Medivir Ab | Prodrugs |
US5289904A (en) * | 1992-08-28 | 1994-03-01 | Harrison Everett W | Sound dampener for disk brakes |
JPH0692987A (ja) * | 1992-09-17 | 1994-04-05 | Tanabe Seiyaku Co Ltd | ウリジン誘導体およびその製法 |
GB9309795D0 (en) * | 1993-05-12 | 1993-06-23 | Rhone Poulenc Chemicals | Preparation of flouro-compounds |
US5717086A (en) * | 1993-05-12 | 1998-02-10 | Rhone-Poulenc Chemicals Limited | Preparation of fluoro-nucleosides and intermediates for use therein |
US5703058A (en) | 1995-01-27 | 1997-12-30 | Emory University | Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent |
US6391859B1 (en) | 1995-01-27 | 2002-05-21 | Emory University | [5-Carboxamido or 5-fluoro]-[2′,3′-unsaturated or 3′-modified]-pyrimidine nucleosides |
US7635690B2 (en) | 1999-01-22 | 2009-12-22 | Emory University | HIV-1 mutations selected for by β-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine |
US7115584B2 (en) | 1999-01-22 | 2006-10-03 | Emory University | HIV-1 mutations selected for by β-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine |
US6132997A (en) * | 1999-05-28 | 2000-10-17 | Agilent Technologies | Method for linear mRNA amplification |
CN102741237B (zh) * | 2010-02-15 | 2015-04-29 | 日产化学工业株式会社 | β-二氢呋喃衍生化合物的制造方法 |
EP2537851B1 (de) | 2010-02-15 | 2015-06-10 | Nissan Chemical Industries, Ltd. | Verfahren zur herstellung von b-glycosid-verbindungen |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0254269A2 (de) * | 1986-07-21 | 1988-01-27 | Daikin Industries, Limited | Polytetrafluoräthylenhaltige Beschichtungsmasse und ihre Verwendung |
EP0311100A2 (de) * | 1987-10-09 | 1989-04-12 | F. Hoffmann-La Roche Ag | Neue Dideoxycytidin-Derivate, ihre Herstellung und Verwendung für Pharmazeutika |
AU7558491A (en) * | 1990-04-04 | 1991-10-30 | Nycomed Imaging As | Nucleoside derivatives |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3322747A (en) * | 1965-04-01 | 1967-05-30 | Merck & Co Inc | Thionocarbonate nucleosides |
US3817982A (en) * | 1971-12-29 | 1974-06-18 | Syntex Inc | 2{40 ,3{40 -unsaturated nucleosides and method of making |
DD279407A1 (de) * | 1986-07-24 | 1990-06-06 | Akad Wissenschaften Ddr | Verfahren zur herstellung eines mittels gegen aids |
EP0286825A3 (de) * | 1987-03-18 | 1989-04-12 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Verwendung von 3'-fluro-3'-deoxythymidine zur Herstellung von medicamenten zur Behandlung von Viruskrankheiten |
ATE108183T1 (de) * | 1987-03-24 | 1994-07-15 | Nycomed Imaging As | 2',3'-dideoxyribofuranoxid-derivate. |
GB8712115D0 (en) * | 1987-05-22 | 1987-06-24 | Hoffmann La Roche | Pyrimidine derivatives |
EP0294113A1 (de) * | 1987-05-29 | 1988-12-07 | The Wellcome Foundation Limited | Therapeutische Nucleoside |
SE8704298D0 (sv) * | 1987-11-03 | 1987-11-03 | Astra Ab | Compounds for use in therapy |
GB8726136D0 (en) * | 1987-11-07 | 1987-12-09 | Wellcome Found | Therapeutic nucleosides |
ZA891076B (en) * | 1988-02-16 | 1990-10-31 | Lilly Co Eli | 2',3'-dideoxy-2',2'-difluoronucleosides |
EP0355031A3 (de) * | 1988-08-17 | 1990-12-27 | MATTHES, Eckart, Dr. | Substituierte Pyrimidinnucleoside, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Mittel |
GB8823320D0 (en) * | 1988-10-05 | 1988-11-09 | Nycomed As | Chemical compounds |
GB8823319D0 (en) * | 1988-10-05 | 1988-11-09 | Nycomed As | Chemical compounds |
-
1990
- 1990-11-06 EP EP90916194A patent/EP0500610A1/de not_active Withdrawn
- 1990-11-06 CA CA002073063A patent/CA2073063A1/en not_active Abandoned
- 1990-11-06 JP JP2514754A patent/JPH05501404A/ja active Pending
- 1990-11-06 WO PCT/EP1990/001853 patent/WO1991006554A1/en not_active Application Discontinuation
- 1990-11-06 AU AU66192/90A patent/AU636678B2/en not_active Ceased
-
1992
- 1992-05-05 OA OA60203A patent/OA09697A/en unknown
- 1992-05-05 FI FI922014A patent/FI922014A0/fi not_active Application Discontinuation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0254269A2 (de) * | 1986-07-21 | 1988-01-27 | Daikin Industries, Limited | Polytetrafluoräthylenhaltige Beschichtungsmasse und ihre Verwendung |
EP0311100A2 (de) * | 1987-10-09 | 1989-04-12 | F. Hoffmann-La Roche Ag | Neue Dideoxycytidin-Derivate, ihre Herstellung und Verwendung für Pharmazeutika |
AU7558491A (en) * | 1990-04-04 | 1991-10-30 | Nycomed Imaging As | Nucleoside derivatives |
Also Published As
Publication number | Publication date |
---|---|
OA09697A (en) | 1993-08-30 |
CA2073063A1 (en) | 1991-05-07 |
AU6619290A (en) | 1991-05-31 |
FI922014A (fi) | 1992-05-05 |
WO1991006554A1 (en) | 1991-05-16 |
EP0500610A1 (de) | 1992-09-02 |
FI922014A0 (fi) | 1992-05-05 |
JPH05501404A (ja) | 1993-03-18 |
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