AU609932B2 - Locally administrable 2-amino-3-benzoyl phenylacetic acid derivatives as therapeutic compositions for inflammatory disease - Google Patents

Locally administrable 2-amino-3-benzoyl phenylacetic acid derivatives as therapeutic compositions for inflammatory disease Download PDF

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Publication number
AU609932B2
AU609932B2 AU28786/89A AU2878689A AU609932B2 AU 609932 B2 AU609932 B2 AU 609932B2 AU 28786/89 A AU28786/89 A AU 28786/89A AU 2878689 A AU2878689 A AU 2878689A AU 609932 B2 AU609932 B2 AU 609932B2
Authority
AU
Australia
Prior art keywords
inflammatory
salt
acid
inflammatory disease
sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU28786/89A
Other languages
English (en)
Other versions
AU2878689A (en
Inventor
Yoshikazu Kuribayashi
Takahiro Ogawa
Akira Ohtori
Kazumichi Ushio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Wyeth LLC
Original Assignee
Senju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11923115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU609932(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Publication of AU2878689A publication Critical patent/AU2878689A/en
Application granted granted Critical
Publication of AU609932B2 publication Critical patent/AU609932B2/en
Assigned to SENJU PHARMACEUTICAL CO., LTD., A.H. ROBINS COMPANY, INCORPORATED reassignment SENJU PHARMACEUTICAL CO., LTD. Request to Amend Deed and Register Assignors: A.H. ROBINS COMPANY, INCORPORATED, SENJU PHARMACEUTICAL CO., LTD.
Assigned to AMERICAN HOME PRODUCTS CORPORATION, SENJU PHARMACEUTICAL CO., LTD. reassignment AMERICAN HOME PRODUCTS CORPORATION Alteration of Name(s) in Register under S187 Assignors: A.H. ROBINS COMPANY, INCORPORATED, SENJU PHARMACEUTICAL CO., LTD.
Assigned to WYETH, SENJU PHARMACEUTICAL CO., LTD. reassignment WYETH Request to Amend Deed and Register Assignors: AMERICAN HOME PRODUCTS CORPORATION, SENJU PHARMACEUTICAL CO., LTD.
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU28786/89A 1988-01-27 1989-01-25 Locally administrable 2-amino-3-benzoyl phenylacetic acid derivatives as therapeutic compositions for inflammatory disease Expired AU609932B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP63-16683 1988-01-27
JP1668388 1988-01-27

Publications (2)

Publication Number Publication Date
AU2878689A AU2878689A (en) 1989-07-27
AU609932B2 true AU609932B2 (en) 1991-05-09

Family

ID=11923115

Family Applications (1)

Application Number Title Priority Date Filing Date
AU28786/89A Expired AU609932B2 (en) 1988-01-27 1989-01-25 Locally administrable 2-amino-3-benzoyl phenylacetic acid derivatives as therapeutic compositions for inflammatory disease

Country Status (12)

Country Link
US (1) US4910225A (enExample)
EP (1) EP0326915B1 (enExample)
JP (1) JP2683676B2 (enExample)
KR (1) KR960005707B1 (enExample)
AT (1) ATE80043T1 (enExample)
AU (1) AU609932B2 (enExample)
CA (1) CA1325382C (enExample)
DE (1) DE68902649T2 (enExample)
ES (1) ES2052784T3 (enExample)
GR (1) GR3005586T3 (enExample)
HK (1) HK162895A (enExample)
PH (1) PH26827A (enExample)

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US5897858A (en) 1994-02-03 1999-04-27 Schering-Plough Healthcare Products, Inc. Nasal spray compositions exhibiting increased retention in the nasal cavity
US5475034A (en) * 1994-06-06 1995-12-12 Alcon Laboratories, Inc. Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
US5895645A (en) * 1995-01-31 1999-04-20 Bausch & Lomb Incorporated Opthalmic solution for artificial tears
RU2116070C1 (ru) * 1996-07-08 1998-07-27 Севиньдж Исмаил кызы Акберова Фармацевтическая композиция
AR020661A1 (es) * 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
DE19961307A1 (de) * 1999-12-18 2001-07-12 Krewel Meuselbach Gmbh Medizinprodukt zur Befeuchtung und Reinigung der Nasenschleimhaut
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
AR030346A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico
US6646003B2 (en) 2001-04-02 2003-11-11 Alcon, Inc. Method of treating ocular inflammatory and angiogenesis-related disorders of the posterior segment of the eye using an amide derivative of flurbiprofen or ketorolac
US7030149B2 (en) 2002-04-19 2006-04-18 Allergan, Inc. Combination of brimonidine timolol for topical ophthalmic use
PL373787A1 (en) * 2002-05-03 2005-09-19 Alcon Inc. Method of treating vascular endothelial growth factor mediated vascular disorders using amfenac or nepafenac
WO2004064828A1 (ja) 2003-01-21 2004-08-05 Senju Pharmaceutical Co., Ltd. ２−アミノ−３−(４−ブロモベンゾイル)フェニル酢酸含有水性液剤
US20030187072A1 (en) * 2003-02-14 2003-10-02 Kapin Michael A. Method of treating angiogenesis-related disorders
WO2004112772A1 (en) * 2003-06-13 2004-12-29 Alcon, Inc. Formulations of non-steroidal anti-inflammatory agents to treat pathologic ocular angiogenesis
JP4674162B2 (ja) * 2003-11-14 2011-04-20 千寿製薬株式会社 アミノグリコシド系抗生物質およびブロムフェナクを含有する水溶液製剤
FR2876581B1 (fr) * 2004-10-20 2007-05-18 Interpharm Dev Composition bioadhesive a liberation programmee
WO2006049250A1 (ja) * 2004-11-05 2006-05-11 Senju Pharmaceutical Co., Ltd. 眼内移行性促進水性点眼剤
TWI358290B (en) * 2004-12-02 2012-02-21 Alcon Inc Topical nepafenac formulations
AU2006244245B2 (en) * 2005-05-10 2010-11-18 Alcon, Inc. Ophthalmic suspension comprising an ophthalmic drug, a poloxamine and a glycol tonicity-adjusting agent, use of said composition for the manufacture of a medicament for treating ophthalmic disorders
SI1885336T1 (sl) * 2005-05-10 2009-08-31 Alcon Inc Suspenzijske formulacije, ki obsegajo aktivno sestavino, poloksamerni ali meroksapolni surfaktant in glikol, in njihova uporaba za pripravo zdravila za zdravljenje oftalmičnih motenj
US20100130580A1 (en) * 2006-01-25 2010-05-27 Aciex Therapeutics, Inc. Formulations and Methods for Treating Dry Eye
US20070254841A1 (en) * 2006-01-25 2007-11-01 Ophthalmic Research Associates, Inc. Formulations and methods for treating dry eye
TW200812575A (en) * 2006-04-28 2008-03-16 Alcon Inc Formulations containing amide derivatives of carboxylic acid NSAIDs for topical administration to the eye
US20080153818A1 (en) * 2006-12-21 2008-06-26 Bingaman David P Methods for preventing inflammation during surgery
US20080153819A1 (en) * 2006-12-21 2008-06-26 Bingaman David P Methods for treating macular edema and pathologic ocular angiogenesis using a neuroprotective agent and a receptor tyrosine kinase inhibitor
US20090105245A1 (en) * 2006-12-21 2009-04-23 Bingaman David P Methods for treating macular edema and ocular angiogenesis using an anti-inflammatory agent and a receptor tyrosine kinase inhibitor
UY31058A1 (es) * 2007-05-01 2008-10-31 Alcon Res Ltd Formulaciones de aminoacido n-halogenado con compuestos antiinflamatorios
CN101754748A (zh) * 2007-05-24 2010-06-23 阿西克斯医疗公司 治疗干眼症的制剂和方法
CA2716110A1 (en) * 2008-02-21 2009-08-27 Tim Mcnamara Ophthalmic nsaids as adjuvants
US8778999B2 (en) 2009-03-05 2014-07-15 Insite Vision Incorporated Non-steroidal anti-inflammatory ophthalmic compositions
US8299295B2 (en) * 2009-10-15 2012-10-30 Johnson Matthey Public Limited Company Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
GB0919757D0 (en) 2009-11-12 2009-12-30 Johnson Matthey Plc Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
US9107888B2 (en) 2011-01-18 2015-08-18 Senju Pharmaceutical Co., Ltd. Aqueous liquid bromfenac composition having preservative efficacy
WO2013166408A1 (en) 2012-05-03 2013-11-07 Kala Pharmaceuticals, Inc. Pharmaceutical nanoparticles showing improved mucosal transport
US9056057B2 (en) 2012-05-03 2015-06-16 Kala Pharmaceuticals, Inc. Nanocrystals, compositions, and methods that aid particle transport in mucus
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
EP2919755B1 (en) 2012-11-19 2018-02-21 Bausch & Lomb Incorporated Aqueous liquid composition containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid
US9353122B2 (en) 2013-02-15 2016-05-31 Kala Pharmaceuticals, Inc. Therapeutic compounds and uses thereof
US9688688B2 (en) 2013-02-20 2017-06-27 Kala Pharmaceuticals, Inc. Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof
US9353123B2 (en) 2013-02-20 2016-05-31 Kala Pharmaceuticals, Inc. Therapeutic compounds and uses thereof
WO2014204952A1 (en) 2013-06-19 2014-12-24 Sentiss Research Center Stable bromfenac solution
US9890173B2 (en) 2013-11-01 2018-02-13 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
KR20160099084A (ko) 2013-11-01 2016-08-19 칼라 파마슈티컬스, 인크. 치료 화합물의 결정질 형태 및 그의 용도
US20170000889A1 (en) 2013-12-12 2017-01-05 Sentiss Pharma Private Limited Stable bromfenac ophthalmic solution
CN106404952B (zh) * 2016-08-31 2019-06-11 辰欣佛都药业（汶上）有限公司 一种溴芬酸钠滴眼液有关物质的测定方法
WO2018048750A1 (en) 2016-09-08 2018-03-15 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
US10253036B2 (en) 2016-09-08 2019-04-09 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
EP3509421A4 (en) 2016-09-08 2020-05-20 Kala Pharmaceuticals, Inc. CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF
JPWO2019117252A1 (ja) * 2017-12-14 2020-12-17 参天製薬株式会社 ２−アミノ−３−（４−ブロモベンゾイル）フェニル酢酸またはその塩を含有する点眼剤
WO2022092868A1 (ko) 2020-10-29 2022-05-05 주식회사태준제약 안과용 조성물
US20240082188A1 (en) 2021-01-21 2024-03-14 Taejoon Pharmaceutical Co., Ltd. Ophthalmic composition

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU512570B2 (en) * 1975-08-13 1980-10-16 A.H. Robins Company, Incorporated Amino benzophenones
JPS58201710A (ja) * 1982-05-18 1983-11-24 Meiji Seika Kaisha Ltd 口腔内用抗炎症ペ−スト剤
AU596813B2 (en) * 1985-10-28 1990-05-17 American Home Products Corporation The use of 2-amino-3-benzoylbenzeneacetic acids and derivatives in pharmaceutical preparations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH577461A5 (enExample) * 1975-08-13 1976-07-15 Robins Co Inc A H
US4568695A (en) * 1983-12-07 1986-02-04 A. H. Robins Company, Incorporated 2-Amino-3-benzoyl-phenethylalcohols and intermediates therefor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU512570B2 (en) * 1975-08-13 1980-10-16 A.H. Robins Company, Incorporated Amino benzophenones
JPS58201710A (ja) * 1982-05-18 1983-11-24 Meiji Seika Kaisha Ltd 口腔内用抗炎症ペ−スト剤
AU596813B2 (en) * 1985-10-28 1990-05-17 American Home Products Corporation The use of 2-amino-3-benzoylbenzeneacetic acids and derivatives in pharmaceutical preparations

Also Published As

Publication number Publication date
JPH02124817A (ja) 1990-05-14
EP0326915A1 (en) 1989-08-09
JP2683676B2 (ja) 1997-12-03
DE68902649D1 (de) 1992-10-08
EP0326915B1 (en) 1992-09-02
GR3005586T3 (enExample) 1993-06-07
KR960005707B1 (ko) 1996-05-01
US4910225A (en) 1990-03-20
AU2878689A (en) 1989-07-27
PH26827A (en) 1992-11-05
KR890011823A (ko) 1989-08-22
ES2052784T3 (es) 1994-07-16
CA1325382C (en) 1993-12-21
ATE80043T1 (de) 1992-09-15
HK162895A (en) 1995-10-27
DE68902649T2 (de) 1993-02-11

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Legal Events

Date Code Title Description
HB Alteration of name in register

Owner name: SENJU PHARMACEUTICAL CO., LTD., WYETH

Free format text: FORMER NAME WAS: SENJU PHARMACEUTICAL CO., LTD., AMERICAN HOME PRODUCTS CORPORATION