ATE80043T1 - Lokal anzuwendende arzneizubereitung zur behandlung von entzuendungserkrankungen. - Google Patents

Lokal anzuwendende arzneizubereitung zur behandlung von entzuendungserkrankungen.

Info

Publication number
ATE80043T1
ATE80043T1 AT89101237T AT89101237T ATE80043T1 AT E80043 T1 ATE80043 T1 AT E80043T1 AT 89101237 T AT89101237 T AT 89101237T AT 89101237 T AT89101237 T AT 89101237T AT E80043 T1 ATE80043 T1 AT E80043T1
Authority
AT
Austria
Prior art keywords
inflammatory
treatment
disease
salt
acid
Prior art date
Application number
AT89101237T
Other languages
English (en)
Inventor
Takahiro Ogawa
Yoshikazu Kuribayashi
Kazumichi Ushio
Akira Ohtori
Original Assignee
Senju Pharma Co
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11923115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE80043(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Senju Pharma Co, Robins Co Inc A H filed Critical Senju Pharma Co
Application granted granted Critical
Publication of ATE80043T1 publication Critical patent/ATE80043T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
AT89101237T 1988-01-27 1989-01-25 Lokal anzuwendende arzneizubereitung zur behandlung von entzuendungserkrankungen. ATE80043T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1668388 1988-01-27
EP89101237A EP0326915B1 (de) 1988-01-27 1989-01-25 Lokal anzuwendende Arzneizubereitung zur Behandlung von Entzündungserkrankungen

Publications (1)

Publication Number Publication Date
ATE80043T1 true ATE80043T1 (de) 1992-09-15

Family

ID=11923115

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89101237T ATE80043T1 (de) 1988-01-27 1989-01-25 Lokal anzuwendende arzneizubereitung zur behandlung von entzuendungserkrankungen.

Country Status (12)

Country Link
US (1) US4910225A (de)
EP (1) EP0326915B1 (de)
JP (1) JP2683676B2 (de)
KR (1) KR960005707B1 (de)
AT (1) ATE80043T1 (de)
AU (1) AU609932B2 (de)
CA (1) CA1325382C (de)
DE (1) DE68902649T2 (de)
ES (1) ES2052784T3 (de)
GR (1) GR3005586T3 (de)
HK (1) HK162895A (de)
PH (1) PH26827A (de)

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US5895645A (en) * 1995-01-31 1999-04-20 Bausch & Lomb Incorporated Opthalmic solution for artificial tears
AR020661A1 (es) * 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
DE19961307A1 (de) * 1999-12-18 2001-07-12 Krewel Meuselbach Gmbh Medizinprodukt zur Befeuchtung und Reinigung der Nasenschleimhaut
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
AR030346A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico
US6646003B2 (en) 2001-04-02 2003-11-11 Alcon, Inc. Method of treating ocular inflammatory and angiogenesis-related disorders of the posterior segment of the eye using an amide derivative of flurbiprofen or ketorolac
US7030149B2 (en) 2002-04-19 2006-04-18 Allergan, Inc. Combination of brimonidine timolol for topical ophthalmic use
JP2005525408A (ja) * 2002-05-03 2005-08-25 アルコン,インコーポレイテッド アンフェナクまたはネパフェナクを用いる血管内皮増殖因子媒介性血管障害の処置方法
CN100341498C (zh) 2003-01-21 2007-10-10 千寿制药株式会社 含有2-氨基-3-(4-溴苯甲酰基)苯乙酸的水成液制剂
US20030187072A1 (en) * 2003-02-14 2003-10-02 Kapin Michael A. Method of treating angiogenesis-related disorders
JP2007500250A (ja) * 2003-06-13 2007-01-11 アルコン,インコーポレイテッド 病的な眼の新脈管形成を処置するための非ステロイド性抗炎症剤の処方物
WO2005046700A1 (ja) * 2003-11-14 2005-05-26 Senju Pharmaceutical Co., Ltd. アミノグリコシド系抗生物質およびブロムフェナクを含有する水溶液製剤
FR2876581B1 (fr) * 2004-10-20 2007-05-18 Interpharm Dev Composition bioadhesive a liberation programmee
KR20130080061A (ko) * 2004-11-05 2013-07-11 센주 세이야꾸 가부시키가이샤 안구 내 이행성 촉진 수성 점안제
TWI358290B (en) * 2004-12-02 2012-02-21 Alcon Inc Topical nepafenac formulations
PL1885336T3 (pl) * 2005-05-10 2009-08-31 Alcon Inc Kompozycja w postaci zawiesiny zawierająca substancję aktywną, poloksamerowy lub meroksapolowy surfaktant i glikol oraz zastosowanie kompozycji do wytwarzania leku do leczenia chorób oczu
CA2607014A1 (en) * 2005-05-10 2006-11-16 Alcon, Inc. Suspension formulations of nepafenac and other ophthalmic drugs for topical treatment of ophthalmic disorders
US20100130580A1 (en) * 2006-01-25 2010-05-27 Aciex Therapeutics, Inc. Formulations and Methods for Treating Dry Eye
EP1981491A4 (de) * 2006-01-25 2009-09-23 Aciex Inc Formulierungen und verfahren zur behandlung von keratoconjunctivitis sicca
TW200812575A (en) * 2006-04-28 2008-03-16 Alcon Inc Formulations containing amide derivatives of carboxylic acid NSAIDs for topical administration to the eye
WO2008080110A1 (en) * 2006-12-21 2008-07-03 Alcon, Inc. Methods for treating macular edema and pathologic ocular angiogenesis using a neuroprotective agent and a receptor tyrosine kinase inhibitor
US20080153818A1 (en) * 2006-12-21 2008-06-26 Bingaman David P Methods for preventing inflammation during surgery
US20090105245A1 (en) * 2006-12-21 2009-04-23 Bingaman David P Methods for treating macular edema and ocular angiogenesis using an anti-inflammatory agent and a receptor tyrosine kinase inhibitor
UY31058A1 (es) * 2007-05-01 2008-10-31 Alcon Res Ltd Formulaciones de aminoacido n-halogenado con compuestos antiinflamatorios
EP2160182A1 (de) * 2007-05-24 2010-03-10 Aciex Therapeutics, Inc. Formulierungen und verfahren zur behandlung von keratoconjunctivitis sicca
BRPI0908502A2 (pt) * 2008-02-21 2017-05-23 Ista Pharmaceuticals aines oftálmicos como adjuvantes
US8778999B2 (en) * 2009-03-05 2014-07-15 Insite Vision Incorporated Non-steroidal anti-inflammatory ophthalmic compositions
GB0919757D0 (en) 2009-11-12 2009-12-30 Johnson Matthey Plc Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
US8299295B2 (en) 2009-10-15 2012-10-30 Johnson Matthey Public Limited Company Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
WO2012099142A1 (ja) 2011-01-18 2012-07-26 千寿製薬株式会社 保存効力を有するブロムフェナク水性液剤組成物
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
JP6360040B2 (ja) 2012-05-03 2018-07-18 カラ ファーマシューティカルズ インコーポレイテッド 粘液浸透性被覆粒子、組成物、医薬組成物、医薬製剤、及びそれらの形成方法
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
EP4008355A1 (de) 2012-05-03 2022-06-08 Kala Pharmaceuticals, Inc. Pharmazeutische nanopartikel mit verbessertem mukosalem transport
MX358604B (es) 2012-11-19 2018-08-28 Bausch & Lomb Composicion liquida acuosa que contiene acido 2-amino-3-(4-bromobenzoil) fenilacetico.
WO2014127214A1 (en) 2013-02-15 2014-08-21 Kala Pharmaceuticals, Inc. Therapeutic compounds and uses thereof
AU2014219024B2 (en) 2013-02-20 2018-04-05 KALA BIO, Inc. Therapeutic compounds and uses thereof
US9688688B2 (en) 2013-02-20 2017-06-27 Kala Pharmaceuticals, Inc. Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof
JP2016522257A (ja) 2013-06-19 2016-07-28 センティス リサーチ センター 安定なブロムフェナク溶液
US9890173B2 (en) 2013-11-01 2018-02-13 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
AU2014342042B2 (en) 2013-11-01 2017-08-17 KALA BIO, Inc. Crystalline forms of therapeutic compounds and uses thereof
US20170000889A1 (en) 2013-12-12 2017-01-05 Sentiss Pharma Private Limited Stable bromfenac ophthalmic solution
CN106404952B (zh) * 2016-08-31 2019-06-11 辰欣佛都药业(汶上)有限公司 一种溴芬酸钠滴眼液有关物质的测定方法
BR112019004463A2 (pt) 2016-09-08 2019-05-28 Kala Pharmaceuticals Inc formas cristalinas de compostos terapêuticos, seus processos de obtenção e seus métodos de uso
US10392399B2 (en) 2016-09-08 2019-08-27 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
CA3036336A1 (en) 2016-09-08 2018-03-15 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
WO2019117252A1 (ja) * 2017-12-14 2019-06-20 参天製薬株式会社 2-アミノ-3-(4-ブロモベンゾイル)フェニル酢酸またはその塩を含有する点眼剤
CA3196559A1 (en) 2020-10-29 2022-05-05 Joon Youb Lee Ophthalmic composition
WO2022158893A2 (ko) 2021-01-21 2022-07-28 주식회사태준제약 점안 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
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AU512570B2 (en) * 1975-08-13 1980-10-16 A.H. Robins Company, Incorporated Amino benzophenones
SE400966B (sv) * 1975-08-13 1978-04-17 Robins Co Inc A H Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror
JPS58201710A (ja) * 1982-05-18 1983-11-24 Meiji Seika Kaisha Ltd 口腔内用抗炎症ペ−スト剤
US4568695A (en) * 1983-12-07 1986-02-04 A. H. Robins Company, Incorporated 2-Amino-3-benzoyl-phenethylalcohols and intermediates therefor
US4683242A (en) * 1985-10-28 1987-07-28 A. H. Robins Company, Incorporated Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters

Also Published As

Publication number Publication date
CA1325382C (en) 1993-12-21
DE68902649D1 (de) 1992-10-08
US4910225A (en) 1990-03-20
GR3005586T3 (de) 1993-06-07
DE68902649T2 (de) 1993-02-11
JPH02124817A (ja) 1990-05-14
ES2052784T3 (es) 1994-07-16
AU609932B2 (en) 1991-05-09
AU2878689A (en) 1989-07-27
EP0326915A1 (de) 1989-08-09
JP2683676B2 (ja) 1997-12-03
HK162895A (en) 1995-10-27
PH26827A (en) 1992-11-05
EP0326915B1 (de) 1992-09-02
KR960005707B1 (ko) 1996-05-01
KR890011823A (ko) 1989-08-22

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
EELA Cancelled due to lapse of time