AU566900B2 - 2,3-dihydro-3-oxo-1h-isoindole derivatives - Google Patents

2,3-dihydro-3-oxo-1h-isoindole derivatives

Info

Publication number
AU566900B2
AU566900B2 AU21183/83A AU2118383A AU566900B2 AU 566900 B2 AU566900 B2 AU 566900B2 AU 21183/83 A AU21183/83 A AU 21183/83A AU 2118383 A AU2118383 A AU 2118383A AU 566900 B2 AU566900 B2 AU 566900B2
Authority
AU
Australia
Prior art keywords
chloro
dihydro
piperidinyl
formula
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU21183/83A
Other languages
English (en)
Other versions
AU2118383A (en
Inventor
Terence M. Dolak
Tellis A. Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of AU2118383A publication Critical patent/AU2118383A/en
Application granted granted Critical
Publication of AU566900B2 publication Critical patent/AU566900B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Suspension Of Electric Lines Or Cables (AREA)
  • Liquid Developers In Electrophotography (AREA)
  • Transformer Cooling (AREA)
AU21183/83A 1982-11-12 1983-11-11 2,3-dihydro-3-oxo-1h-isoindole derivatives Ceased AU566900B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/441,204 US4495194A (en) 1982-11-12 1982-11-12 Antihypertensive isoindole derivatives
US441204 1982-11-12

Related Child Applications (2)

Application Number Title Priority Date Filing Date
AU79369/87A Division AU604756B2 (en) 1982-11-12 1987-10-05 Isoindoline derivatives and preparation thereof
AU63039/90A Division AU636164B2 (en) 1982-11-12 1990-09-20 2,3-dihydro-1-hydroxy-3-oxo-2-(1-substituted-4-piperidinyl)- 1N-isoindole derivatives

Publications (2)

Publication Number Publication Date
AU2118383A AU2118383A (en) 1984-05-17
AU566900B2 true AU566900B2 (en) 1987-11-05

Family

ID=23751955

Family Applications (2)

Application Number Title Priority Date Filing Date
AU21183/83A Ceased AU566900B2 (en) 1982-11-12 1983-11-11 2,3-dihydro-3-oxo-1h-isoindole derivatives
AU79369/87A Ceased AU604756B2 (en) 1982-11-12 1987-10-05 Isoindoline derivatives and preparation thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU79369/87A Ceased AU604756B2 (en) 1982-11-12 1987-10-05 Isoindoline derivatives and preparation thereof

Country Status (15)

Country Link
US (1) US4495194A (enExample)
EP (1) EP0111397B1 (enExample)
JP (2) JPS59101483A (enExample)
KR (1) KR870001168B1 (enExample)
AT (1) ATE40999T1 (enExample)
AU (2) AU566900B2 (enExample)
CA (1) CA1246081A (enExample)
DE (1) DE3379267D1 (enExample)
DK (2) DK165116C (enExample)
ES (5) ES527146A0 (enExample)
FI (1) FI82691C (enExample)
GR (1) GR81279B (enExample)
IE (1) IE56231B1 (enExample)
PT (1) PT77651B (enExample)
ZA (1) ZA838361B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU636164B2 (en) * 1982-11-12 1993-04-22 Bristol-Myers Squibb Company 2,3-dihydro-1-hydroxy-3-oxo-2-(1-substituted-4-piperidinyl)- 1N-isoindole derivatives

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0351283A1 (fr) * 1988-07-12 1990-01-17 Synthelabo Dérivés de [(pipéridinyl-4) méthyl]-2 dihydro-2,3 1H-isoindole et tétrahydro-2,3,4,5 1H-benzazépines, leur préparation et leur application en thérapeutique
EP0497843A4 (en) * 1989-10-27 1992-09-23 The Du Pont Merck Pharmaceutical Company (n-phthalimidoalkyl) piperidines
US5356906A (en) * 1989-10-27 1994-10-18 The Du Pont Merck Pharmaceutical Company (N-phthalimidoalkyl) piperidines useful as treatments for psychosis
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
NZ521576A (en) * 2000-02-29 2005-06-24 Mitsubishi Pharma Corp Novel cyclic amide derivatives
US8939859B2 (en) 2012-10-19 2015-01-27 Caterpillar Inc. Torque converter with stator clutch

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6151380A (en) * 1979-08-27 1981-03-05 Astra Lakemedel Aktiebolag Phthalimidine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3579524A (en) * 1968-06-05 1971-05-18 Miles Lab 2-aminoalkyl derivatives of phthalimidines
GB1486104A (en) * 1975-01-23 1977-09-21 Wyeth John & Brother Ltd Phthalimidopiperidine derivatives
IL52413A (en) * 1977-06-29 1980-01-31 Teva Pharma Process for the preparazione of 5-chloro-6-sulfamyl-isoindolinone derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6151380A (en) * 1979-08-27 1981-03-05 Astra Lakemedel Aktiebolag Phthalimidine derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU636164B2 (en) * 1982-11-12 1993-04-22 Bristol-Myers Squibb Company 2,3-dihydro-1-hydroxy-3-oxo-2-(1-substituted-4-piperidinyl)- 1N-isoindole derivatives

Also Published As

Publication number Publication date
US4495194A (en) 1985-01-22
KR870001168B1 (ko) 1987-06-15
ES8504172A1 (es) 1985-04-16
PT77651B (en) 1986-05-12
DK517383D0 (da) 1983-11-11
IE832638L (en) 1984-05-12
ZA838361B (en) 1984-06-27
EP0111397B1 (en) 1989-03-01
GR81279B (enExample) 1984-12-11
DK517383A (da) 1984-05-13
DK153690D0 (da) 1990-06-22
ES533937A0 (es) 1985-10-16
CA1268767C (enExample) 1990-05-08
ES533936A0 (es) 1985-10-16
FI834112L (fi) 1984-05-13
ES533939A0 (es) 1985-10-16
DE3379267D1 (en) 1989-04-06
CA1246081A (en) 1988-12-06
ES8600743A1 (es) 1985-10-16
AU2118383A (en) 1984-05-17
DK153690A (da) 1990-06-22
AU604756B2 (en) 1991-01-03
ATE40999T1 (de) 1989-03-15
ES8600741A1 (es) 1985-10-16
AU7936987A (en) 1988-01-14
ES8600740A1 (es) 1985-10-16
FI834112A0 (fi) 1983-11-09
JPS59101483A (ja) 1984-06-12
JPH0545591B2 (enExample) 1993-07-09
IE56231B1 (en) 1991-05-22
FI82691C (fi) 1991-04-10
JPH0450309B2 (enExample) 1992-08-13
PT77651A (en) 1983-12-01
ES527146A0 (es) 1985-04-16
EP0111397A1 (en) 1984-06-20
ES8600742A1 (es) 1985-10-16
KR840006643A (ko) 1984-12-01
FI82691B (fi) 1990-12-31
DK165116B (da) 1992-10-12
JPH051058A (ja) 1993-01-08
DK165116C (da) 1993-03-01
ES533938A0 (es) 1985-10-16

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