ES533937A0 - Un procedimiento para la preparacion de nuevos derivados de isoindol - Google Patents
Un procedimiento para la preparacion de nuevos derivados de isoindolInfo
- Publication number
- ES533937A0 ES533937A0 ES533937A ES533937A ES533937A0 ES 533937 A0 ES533937 A0 ES 533937A0 ES 533937 A ES533937 A ES 533937A ES 533937 A ES533937 A ES 533937A ES 533937 A0 ES533937 A0 ES 533937A0
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- preparation
- new
- isoindole
- isoindol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- VHMICKWLTGFITH-UHFFFAOYSA-N 2H-isoindole Chemical class C1=CC=CC2=CNC=C21 VHMICKWLTGFITH-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical group 0.000 abstract 2
- OIXLFMOEDWMDMT-UHFFFAOYSA-N 2-(1-benzylpiperidin-4-yl)-6-chloro-3-oxo-1h-isoindole-5-sulfonamide Chemical compound C1C=2C=C(Cl)C(S(=O)(=O)N)=CC=2C(=O)N1C(CC1)CCN1CC1=CC=CC=C1 OIXLFMOEDWMDMT-UHFFFAOYSA-N 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- XKJCHHZQLQNZHY-UHFFFAOYSA-N phthalimide Chemical compound C1=CC=C2C(=O)NC(=O)C2=C1 XKJCHHZQLQNZHY-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Liquid Developers In Electrophotography (AREA)
- Transformer Cooling (AREA)
- Suspension Of Electric Lines Or Cables (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/441,204 US4495194A (en) | 1982-11-12 | 1982-11-12 | Antihypertensive isoindole derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8600741A1 ES8600741A1 (es) | 1985-10-16 |
| ES533937A0 true ES533937A0 (es) | 1985-10-16 |
Family
ID=23751955
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES527146A Granted ES527146A0 (es) | 1982-11-12 | 1983-11-10 | Un procedimiento para la preparacion de nuevos derivados de isoindol. |
| ES533939A Expired ES8600743A1 (es) | 1982-11-12 | 1984-07-02 | Un procedimiento de preparacion de nuevos derivados de 4-aminopiperidina |
| ES533938A Granted ES533938A0 (es) | 1982-11-12 | 1984-07-02 | Un procedimiento para la preparacion de nuevos derivados de isoindol |
| ES533936A Expired ES8600740A1 (es) | 1982-11-12 | 1984-07-02 | Un procedimiento para la preparacion de nuevos derivados de isoindol |
| ES533937A Granted ES533937A0 (es) | 1982-11-12 | 1984-07-02 | Un procedimiento para la preparacion de nuevos derivados de isoindol |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES527146A Granted ES527146A0 (es) | 1982-11-12 | 1983-11-10 | Un procedimiento para la preparacion de nuevos derivados de isoindol. |
| ES533939A Expired ES8600743A1 (es) | 1982-11-12 | 1984-07-02 | Un procedimiento de preparacion de nuevos derivados de 4-aminopiperidina |
| ES533938A Granted ES533938A0 (es) | 1982-11-12 | 1984-07-02 | Un procedimiento para la preparacion de nuevos derivados de isoindol |
| ES533936A Expired ES8600740A1 (es) | 1982-11-12 | 1984-07-02 | Un procedimiento para la preparacion de nuevos derivados de isoindol |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4495194A (es) |
| EP (1) | EP0111397B1 (es) |
| JP (2) | JPS59101483A (es) |
| KR (1) | KR870001168B1 (es) |
| AT (1) | ATE40999T1 (es) |
| AU (2) | AU566900B2 (es) |
| CA (1) | CA1246081A (es) |
| DE (1) | DE3379267D1 (es) |
| DK (2) | DK165116C (es) |
| ES (5) | ES527146A0 (es) |
| FI (1) | FI82691C (es) |
| GR (1) | GR81279B (es) |
| IE (1) | IE56231B1 (es) |
| PT (1) | PT77651B (es) |
| ZA (1) | ZA838361B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU636164B2 (en) * | 1982-11-12 | 1993-04-22 | Bristol-Myers Squibb Company | 2,3-dihydro-1-hydroxy-3-oxo-2-(1-substituted-4-piperidinyl)- 1N-isoindole derivatives |
| EP0351283A1 (fr) * | 1988-07-12 | 1990-01-17 | Synthelabo | Dérivés de [(pipéridinyl-4) méthyl]-2 dihydro-2,3 1H-isoindole et tétrahydro-2,3,4,5 1H-benzazépines, leur préparation et leur application en thérapeutique |
| EP0497843A4 (en) * | 1989-10-27 | 1992-09-23 | The Du Pont Merck Pharmaceutical Company | (n-phthalimidoalkyl) piperidines |
| US5356906A (en) * | 1989-10-27 | 1994-10-18 | The Du Pont Merck Pharmaceutical Company | (N-phthalimidoalkyl) piperidines useful as treatments for psychosis |
| JP2807577B2 (ja) * | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| CN100384836C (zh) * | 2000-02-29 | 2008-04-30 | 三菱制药株式会社 | 新型环状酰胺衍生物 |
| US8939859B2 (en) | 2012-10-19 | 2015-01-27 | Caterpillar Inc. | Torque converter with stator clutch |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3579524A (en) * | 1968-06-05 | 1971-05-18 | Miles Lab | 2-aminoalkyl derivatives of phthalimidines |
| GB1486104A (en) * | 1975-01-23 | 1977-09-21 | Wyeth John & Brother Ltd | Phthalimidopiperidine derivatives |
| IL52413A (en) * | 1977-06-29 | 1980-01-31 | Teva Pharma | Process for the preparazione of 5-chloro-6-sulfamyl-isoindolinone derivatives |
| SE7907121L (sv) * | 1979-08-27 | 1981-02-28 | Astra Laekemedel Ab | Ftalimidinderivat |
-
1982
- 1982-11-12 US US06/441,204 patent/US4495194A/en not_active Expired - Fee Related
-
1983
- 1983-11-09 FI FI834112A patent/FI82691C/fi not_active IP Right Cessation
- 1983-11-09 GR GR72928A patent/GR81279B/el unknown
- 1983-11-09 ZA ZA838361A patent/ZA838361B/xx unknown
- 1983-11-09 CA CA000440844A patent/CA1246081A/en not_active Expired
- 1983-11-10 ES ES527146A patent/ES527146A0/es active Granted
- 1983-11-11 AT AT83306911T patent/ATE40999T1/de active
- 1983-11-11 IE IE2638/83A patent/IE56231B1/en not_active IP Right Cessation
- 1983-11-11 JP JP58211113A patent/JPS59101483A/ja active Granted
- 1983-11-11 DE DE8383306911T patent/DE3379267D1/de not_active Expired
- 1983-11-11 AU AU21183/83A patent/AU566900B2/en not_active Ceased
- 1983-11-11 PT PT77651A patent/PT77651B/pt not_active IP Right Cessation
- 1983-11-11 EP EP83306911A patent/EP0111397B1/en not_active Expired
- 1983-11-11 DK DK517383A patent/DK165116C/da not_active IP Right Cessation
- 1983-11-12 KR KR1019830005375A patent/KR870001168B1/ko not_active IP Right Cessation
-
1984
- 1984-07-02 ES ES533939A patent/ES8600743A1/es not_active Expired
- 1984-07-02 ES ES533938A patent/ES533938A0/es active Granted
- 1984-07-02 ES ES533936A patent/ES8600740A1/es not_active Expired
- 1984-07-02 ES ES533937A patent/ES533937A0/es active Granted
-
1987
- 1987-10-05 AU AU79369/87A patent/AU604756B2/en not_active Ceased
-
1990
- 1990-06-22 DK DK153690A patent/DK153690D0/da not_active IP Right Cessation
-
1991
- 1991-10-30 JP JP3310030A patent/JPH051058A/ja active Granted
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970401 |